2024
Global Disparities in the Characteristics and Outcomes of Leukemia Clinical Trials: A Cross-Sectional Study of the ClinicalTrials.gov Database.
Alhajahjeh A, Rotter L, Stempel J, Grimshaw A, Bewersdorf J, Blaha O, Kewan T, Podoltsev N, Shallis R, Mendez L, Stahl M, Zeidan A. Global Disparities in the Characteristics and Outcomes of Leukemia Clinical Trials: A Cross-Sectional Study of the ClinicalTrials.gov Database. JCO Global Oncology 2024, 10: e2400316. PMID: 39621951, DOI: 10.1200/go-24-00316.Peer-Reviewed Original ResearchMeSH KeywordsClinical Trials as TopicCross-Sectional StudiesDatabases, FactualDeveloped CountriesDeveloping CountriesHealthcare DisparitiesHumansLeukemia
2022
Clinical Presentation, Risk Factors, and Outcomes of Immune Effector Cell-Associated Neurotoxicity Syndrome Following Chimeric Antigen Receptor T Cell Therapy: A Systematic Review
Grant SJ, Grimshaw AA, Silberstein J, Murdaugh D, Wildes TM, Rosko AE, Giri S. Clinical Presentation, Risk Factors, and Outcomes of Immune Effector Cell-Associated Neurotoxicity Syndrome Following Chimeric Antigen Receptor T Cell Therapy: A Systematic Review. Transplantation And Cellular Therapy 2022, 28: 294-302. PMID: 35288347, PMCID: PMC9197870, DOI: 10.1016/j.jtct.2022.03.006.Peer-Reviewed Original ResearchConceptsImmune effector cell-associated neurotoxicity syndromeCAR T-cell therapyT-cell therapyLong-term outcomesHematologic malignanciesCell therapyClinical presentationLymphocytic leukemiaCAR-T cell therapy recipientsChimeric antigen receptor T-cell therapyJoanna Briggs Institute critical appraisal toolsDiffuse large B-cell lymphomaCAR T-cell productsLarge B-cell lymphomaCytokine release syndromeRefractory hematologic malignanciesLong-term sequelaeSubset of patientsC-reactive proteinCommon hematologic malignancyLife-threatening conditionNon-Hodgkin lymphomaCross-trial comparisonsAcute lymphocytic leukemiaChronic lymphocytic leukemia