2023
Estimated mortality with early empirical antibiotic coverage of methicillin-resistant Staphylococcus aureus in hospitalized patients with bacterial infections: a systematic review and meta-analysis
Carey G, Holleck J, Alshaeba S, Jayakrishnan R, Gordon K, Grimshaw A, Gunderson C. Estimated mortality with early empirical antibiotic coverage of methicillin-resistant Staphylococcus aureus in hospitalized patients with bacterial infections: a systematic review and meta-analysis. Journal Of Antimicrobial Chemotherapy 2023, 78: 1150-1159. PMID: 36964648, DOI: 10.1093/jac/dkad078.Peer-Reviewed Original ResearchConceptsCommon infectious syndromesEmpirical antibioticsPrevalence of MRSAInfectious syndromesMRSA infectionIll patientsMortality rateSystematic reviewAbsolute mortality benefitAnti-MRSA therapyEmpirical antibiotic coverageLow-risk infectionsSoft tissue infectionsUrinary tract infectionAbsolute risk reductionMethicillin-resistant Staphylococcus aureusCatheter-related infectionsStudy of patientsBaseline mortality ratesSystematic literature searchWeb of ScienceMRSA coverageAntibiotic coverageEmpirical antimicrobialsMortality benefit
2022
SARS–CoV‐2 Infection and COVID‐19 Outcomes in Rheumatic Diseases: A Systematic Literature Review and Meta‐Analysis
Conway R, Grimshaw AA, Konig MF, Putman M, Duarte‐García A, Tseng LY, Cabrera DM, Chock YPE, Degirmenci HB, Duff E, Egeli BH, Graef ER, Gupta A, Harkins P, Hoyer BF, Jayatilleke A, Jin S, Kasia C, Khilnani A, Kilian A, Kim AHJ, Lin CMA, Low C, Proulx L, Sattui SE, Singh N, Sparks JA, Tam H, Ugarte‐Gil M, Ung N, Wang K, Wise LM, Yang Z, Young KJ, Liew JW, Grainger R, Wallace ZS, Hsieh E, Alliance T. SARS–CoV‐2 Infection and COVID‐19 Outcomes in Rheumatic Diseases: A Systematic Literature Review and Meta‐Analysis. Arthritis & Rheumatology 2022, 74: 766-775. PMID: 34807517, PMCID: PMC9011807, DOI: 10.1002/art.42030.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionMechanical ventilationRisk ratioOdds ratioMortality rateCOVID-19 disease severityJoanna Briggs Institute critical appraisal toolsCOVID-19Odds of hospitalizationNewcastle-Ottawa ScaleCOVID-19 outcomesRandom-effects modelCritical appraisal toolMantel-Haenszel formulaSystematic literature reviewAdjusted riskICU admissionRMD patientsClinical outcomesRheumatic diseasesMethodologic qualityRelative riskObservational studyGeneral populationLower risk
2021
Effect of institutional transcatheter aortic valve replacement volume on mortality: A systematic review and meta‐analysis
Kir D, Shapero K, Chatterjee S, Grimshaw A, Oddleifson A, Spatz ES, Goldsweig AM, Desai NR. Effect of institutional transcatheter aortic valve replacement volume on mortality: A systematic review and meta‐analysis. Catheterization And Cardiovascular Interventions 2021, 98: e453-e461. PMID: 33565695, DOI: 10.1002/ccd.29502.Peer-Reviewed Original ResearchConceptsLow-volume centersVolume centersTitles/abstractsPatient outcomesTAVR centersTAVR volumeCause mortalitySystematic reviewHigh-volume centersIntermediate-volume centersReplacement volumeFull-text studiesCause mortality dataStrong referral networkFree-text termsSystematic literature searchPre-specified criteriaEligible studiesProcedural volumeExclusion criteriaMortality rateTAVRLiterature searchMortality dataRelevant articles
2020
Rate of Preventable Mortality in Hospitalized Patients: a Systematic Review and Meta-analysis
Rodwin BA, Bilan VP, Merchant NB, Steffens CG, Grimshaw AA, Bastian LA, Gunderson CG. Rate of Preventable Mortality in Hospitalized Patients: a Systematic Review and Meta-analysis. Journal Of General Internal Medicine 2020, 35: 2099-2106. PMID: 31965525, PMCID: PMC7351940, DOI: 10.1007/s11606-019-05592-5.Peer-Reviewed Original ResearchConceptsInpatient deathPreventable mortalityPreventable deathsMortality rateHospital mortality rateLife expectancyRandom-effects modelSystematic literature searchNumber of deathsWeb of ScienceHospital deathAdult patientsHospitalized patientsResultsSixteen studiesCase seriesPooled rateCochrane LibraryInclusion criteriaPatientsMeta-AnalysisSystematic reviewLiterature searchData extractionMortalityDeath