2024
Thirty-Day Outcomes from the Disrupt PAD BTK II Study of the Shockwave Intravascular Lithotripsy System for Treatment of Calcified Below-the-Knee Peripheral Arterial Disease
Chandra V, Lansky A, Sayfo S, Shammas N, Soukas P, Park J, Siah M, Babaev A, Shields R, West N, Armstrong E. Thirty-Day Outcomes from the Disrupt PAD BTK II Study of the Shockwave Intravascular Lithotripsy System for Treatment of Calcified Below-the-Knee Peripheral Arterial Disease. Journal Of Vascular Surgery 2024 PMID: 39536842, DOI: 10.1016/j.jvs.2024.11.003.Peer-Reviewed Original ResearchPost-operative deathsII studyPercutaneous transluminal angioplastyProcedural successBTK lesionsResidual stenosisFollow-upIntravascular lithotripsyIndex limbCore labRutherford category 3Treated target lesionsUltrasound core laboratoryInterventional clinical studyAngiographic core labThirty-day outcomesMinimal adverse eventsTarget lesion lengthSevere lesion calcificationIVL systemAdverse limb eventsOptimal standard of careStandard of carePeripheral arterial diseaseVascuQol scores
2023
Sex-specific analysis of intravascular lithotripsy for peripheral artery disease from the Disrupt PAD III observational study
Nagpal S, Altin S, McGinigle K, Mangalmurti S, Adams G, Shammas N, Mehrle A, Soukas P, Bertolet B, Lansky A. Sex-specific analysis of intravascular lithotripsy for peripheral artery disease from the Disrupt PAD III observational study. Journal Of Vascular Surgery 2023, 79: 358-365. PMID: 37925039, DOI: 10.1016/j.jvs.2023.10.058.Peer-Reviewed Original ResearchPeripheral artery diseaseLower extremity peripheral artery diseaseIntravascular lithotripsyResidual stenosisArtery diseaseAcute safetyObservational studyLow ankle-brachial indexUse of IVLChronic limb-threatening ischemiaFinal residual stenosisPeripheral intravascular lithotripsySevere lesion calcificationAnkle-brachial indexLimb-threatening ischemiaReference vessel sizeAbrupt vessel closureHigh complication rateRates of diabetesFisher's exact testSex-specific analysesAngiographic complicationsAtherectomy useIVL treatmentEfficacy outcomes
2020
Safety and effectiveness of coronary intravascular lithotripsy in eccentric calcified coronary lesions: a patient-level pooled analysis from the Disrupt CAD I and CAD II Studies
Blachutzik F, Honton B, Escaned J, Hill JM, Werner N, Banning AP, Lansky AJ, Schlattner S, De Bruyne B, Di Mario C, Dörr O, Hamm C, Nef HM. Safety and effectiveness of coronary intravascular lithotripsy in eccentric calcified coronary lesions: a patient-level pooled analysis from the Disrupt CAD I and CAD II Studies. Clinical Research In Cardiology 2020, 110: 228-236. PMID: 32948882, PMCID: PMC7862504, DOI: 10.1007/s00392-020-01737-3.Peer-Reviewed Original ResearchConceptsCoronary intravascular lithotripsyIntravascular lithotripsyCalcified coronary lesionsII studyResidual stenosisCoronary lesionsCAD IPooled patient-level analysisFinal residual stenosisPercent residual stenosisFlow-limiting dissectionPatient-level analysisPatient-level dataHospital MACEIVL useAcute gainClinical outcomesConcentric lesionsEccentric lesionsCalcified lesionsAbrupt closureReflow eventsResultsClinical successStenosisConcentric stenosisIntravascular Lithotripsy for Treatment of Calcified Lower Extremity Arterial Stenosis: Initial Analysis of the Disrupt PAD III Study
Adams G, Shammas N, Mangalmurti S, Bernardo NL, Miller WE, Soukas PA, Parikh SA, Armstrong EJ, Tepe G, Lansky A, Gray WA. Intravascular Lithotripsy for Treatment of Calcified Lower Extremity Arterial Stenosis: Initial Analysis of the Disrupt PAD III Study. Journal Of Endovascular Therapy 2020, 27: 473-480. PMID: 32242768, PMCID: PMC7288854, DOI: 10.1177/1526602820914598.Peer-Reviewed Original ResearchConceptsPeripheral artery diseasePeripheral intravascular lithotripsyIntravascular lithotripsyResidual stenosisAcute gainObservational studyChronic limb-threatening ischemiaSingle-arm observational studyBalloon-based technologiesHigher acute gainMean residual stenosisLimb-threatening ischemiaLower limb arteriesEnd of procedureSevere arterial calcificationLow residual stenosisReal-world studyAngiographic complicationsDistal embolizationHospital dischargeIII studyArtery diseaseThrombotic eventsEndovascular treatmentLimb arteries
2019
Treating Post-Angioplasty Dissection in the Femoropopliteal Arteries Using the Tack Endovascular System 12-Month Results From the TOBA II Study
Gray WA, Cardenas JA, Brodmann M, Werner M, Bernardo NI, George JC, Lansky A. Treating Post-Angioplasty Dissection in the Femoropopliteal Arteries Using the Tack Endovascular System 12-Month Results From the TOBA II Study. JACC Cardiovascular Interventions 2019, 12: 2375-2384. PMID: 31806218, DOI: 10.1016/j.jcin.2019.08.005.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, BalloonBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationEuropeFemaleFemoral ArteryHumansMaleMiddle AgedPeripheral Arterial DiseasePopliteal ArteryProspective StudiesProsthesis DesignRisk FactorsStentsTime FactorsTreatment OutcomeUnited StatesVascular Access DevicesVascular PatencyVascular System InjuriesConceptsProximal popliteal arteryDrug-coated balloonsSuperficial femoral arteryPlain balloonPopliteal arteryFemoral arteryTack Endovascular SystemLong-term outcomesDCB angioplastyEfficacy endpointPrimary patencyResidual stenosisRestenotic lesionsMulticenter studyFemoropopliteal arteriesEndovascular SystemAngioplastyArteryClassification 2DissectionLesionsBalloonStenosisPatencyPatients
2018
Primary outcomes and mechanism of action of intravascular lithotripsy in calcified, femoropopliteal lesions: Results of Disrupt PAD II
Brodmann M, Werner M, Holden A, Tepe G, Scheinert D, Schwindt A, Wolf F, Jaff M, Lansky A, Zeller T. Primary outcomes and mechanism of action of intravascular lithotripsy in calcified, femoropopliteal lesions: Results of Disrupt PAD II. Catheterization And Cardiovascular Interventions 2018, 93: 335-342. PMID: 30474206, DOI: 10.1002/ccd.27943.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overEuropeFemaleFemoral ArteryHumansLithotripsyMaleMiddle AgedNew ZealandPeripheral Arterial DiseasePopliteal ArteryProgression-Free SurvivalProspective StudiesRetreatmentRisk FactorsSeverity of Illness IndexTime FactorsUltrasonic TherapyVascular CalcificationVascular PatencyConceptsMajor adverse eventsIntravascular lithotripsyPrimary patencyDuplex ultrasonographyPAD IIAcute procedure successFinal residual stenosisPrimary effectiveness endpointPrimary safety endpointKey secondary endpointPeripheral arterial stenosisMulti-center studySonic pressure wavesMechanism of actionCompelling safetyEffectiveness endpointAnti-proliferative therapiesSafety endpointSecondary endpointsVascular complicationsAdverse eventsFemoropopliteal lesionsResidual stenosisPrimary outcomeAcute gain
2011
Intravascular Ultrasound Findings of Early Stent Thrombosis After Primary Percutaneous Intervention in Acute Myocardial Infarction
Choi SY, Witzenbichler B, Maehara A, Lansky AJ, Guagliumi G, Brodie B, Kellett MA, Dressler O, Parise H, Mehran R, Dangas GD, Mintz GS, Stone GW. Intravascular Ultrasound Findings of Early Stent Thrombosis After Primary Percutaneous Intervention in Acute Myocardial Infarction. Circulation Cardiovascular Interventions 2011, 4: 239-247. PMID: 21586693, DOI: 10.1161/circinterventions.110.959791.Peer-Reviewed Original ResearchConceptsEarly stent thrombosisMinimum lumen areaSignificant residual stenosisStent thrombosisAcute myocardial infarctionResidual stenosisEdge dissectionLumen areaAcute malappositionMyocardial infarctionTissue protrusionAcute Myocardial Infarction StudyIntravascular ultrasound predictorsSignificant edge dissectionPrimary percutaneous interventionIntravascular ultrasound findingsMyocardial Infarction StudyStent edge dissectionFinal lumen areaSmaller stent areaFormal substudyHarmonizing OutcomesIVUS predictorsOutflow diseaseStable angina
1998
Final Results of the Balloon vs Optimal Atherectomy Trial (BOAT)
Baim D, Cutlip D, Sharma S, Ho K, Fortuna R, Schreiber T, Feldman R, Shani J, Senerchia C, Zhang Y, Lansky A, Popma J, Kuntz R. Final Results of the Balloon vs Optimal Atherectomy Trial (BOAT). Circulation 1998, 97: 322-331. PMID: 9468205, DOI: 10.1161/01.cir.97.4.322.Peer-Reviewed Original ResearchConceptsAngiographic restenosisBalloon angioplastyHigh short-term successPrespecified primary end pointLower angiographic restenosisNative vessel lesionsSingle de novoPrimary end pointTarget vessel failureTarget vessel revascularizationResidual diameter stenosisLate clinical eventsConventional balloon angioplastyCreatine kinase-MBLow residual stenosisSignificant reductionHospital complicationsResidual stenosisLesion successMajor complicationsAngiographic restudyDiameter stenosisVessel lesionsClinical eventsLong-term benefits
1996
Angiographic and Clinical Outcome after Cutting Balloon Angioplasty.
Popma J, Lansky A, Purkayastha D, Hall L, Bonan R. Angiographic and Clinical Outcome after Cutting Balloon Angioplasty. Journal Of Invasive Cardiology 1996, 8 Suppl A: 12a-19a. PMID: 10785760.Peer-Reviewed Original ResearchBalloon angioplastyConventional balloon angioplastyResidual stenosisClinical outcomesBalloon useDiameter stenosisArtery ratioNon-complex coronary artery diseaseComplex coronary artery diseaseCutting Balloon AngioplastyReference artery sizeCoronary artery diseaseMinimal lumen diameterCore laboratory analysisPrevention of restenosisAngiographic core laboratory analysisNew device angioplastyHospital complicationsOstial locationAngiographic successArtery diseaseConsecutive patientsArtery sizeSignificant inverse relationshipMorphologic findings