2023
ASPECTS evolution after endovascular successful reperfusion in the early and extended time window.
Anadani M, Finitsis S, Pop R, Darcourt J, Clarençon F, Richard S, de Havenon A, Liebeskind D, Marnat G, Bourcier R, Sibon I, Dargazanli C, Arquizan C, Blanc R, Lapergue B, Consoli A, Eugène F, Vannier S, Caroff J, Denier C, Boulanger M, Gauberti M, Saleme S, Macian F, Rosso C, Turc G, Ozkul-Wermester O, Papagiannaki C, Olivot J, Le Bras A, Evain S, Wolff V, Timsit S, Gentric J, Bourdain F, Veunac L, Maïer B, Ben Hassen W, Gory B. ASPECTS evolution after endovascular successful reperfusion in the early and extended time window. Interventional Neuroradiology 2023, 15910199231196953. PMID: 37671452, DOI: 10.1177/15910199231196953.Peer-Reviewed Original ResearchSuccessful reperfusionEndovascular therapySafety outcomesAlberta Stroke Program Early CTAnterior circulation large vessel occlusionEarly neurological improvementProspective multicenter registrySuccessful endovascular therapyLarge vessel occlusionExtended time windowIncomplete reperfusionEarly CTMulticenter registryNeurological improvementStroke severityComplete reperfusionParenchymal hemorrhageStroke patientsExcellent outcomesInfarct extentVessel occlusionFavorable outcomeGood collateralsReliable imaging biomarkerReperfusion
2022
Safety and efficacy of intensive systolic blood pressure lowering after successful endovascular therapy: a post hoc analysis of the BP TARGET trial
Anadani M, Maier B, Escalard S, Labreuche J, de Havenon A, Sabben C, Lapergue B, Mistry EA, Gory B, Spiotta AM, Richard S, Sibon I, Desilles JP, Blanc R, Piotin M, Mazighi M. Safety and efficacy of intensive systolic blood pressure lowering after successful endovascular therapy: a post hoc analysis of the BP TARGET trial. Journal Of NeuroInterventional Surgery 2022, 15: e142-e147. PMID: 36220337, DOI: 10.1136/jnis-2022-019130.Peer-Reviewed Original ResearchConceptsIntensive SBP treatmentHistory of hypertensionBlood pressure treatmentSuccessful endovascular therapyIntravenous thrombolysisLocation of occlusionEndovascular therapySBP treatmentAdmission SBPDiabetic patientsIntensive blood pressure loweringIntensive systolic blood pressureAcute ischemic stroke trialsTarget trialsEffect of SBPBlood pressure loweringNon-diabetic patientsFavorable functional outcomeSystolic blood pressureIschemic stroke trialsSite of occlusionIntensive SBPRecanalization statusSuccessful reperfusionBlood pressure
2021
Blood Pressure Management After Endovascular Thrombectomy
Peng TJ, Ortega-Gutiérrez S, de Havenon A, Petersen NH. Blood Pressure Management After Endovascular Thrombectomy. Frontiers In Neurology 2021, 12: 723461. PMID: 34539562, PMCID: PMC8446280, DOI: 10.3389/fneur.2021.723461.Peer-Reviewed Original ResearchEndovascular thrombectomyBlood pressureBP targetsAnterior circulation large vessel occlusion strokeImmediate post-stroke periodLower blood pressure targetsLarge vessel occlusion strokeAdequate BP targetsBlood pressure targetsOptimal hemodynamic managementOverall hemodynamic statusPost-stroke periodAcute stroke therapyBlood pressure managementDegree of reperfusionPotential neuroprotective strategiesIndividual patient factorsStandard of careBlood pressure optimizationNovel treatment strategiesWorse clinical recoveryBP controlKey observational studiesSuccessful reperfusionClinical recoveryEndovascular Therapy of Anterior Circulation Tandem Occlusions
Anadani M, Marnat G, Consoli A, Papanagiotou P, Nogueira RG, Siddiqui A, Ribo M, Spiotta AM, Bourcier R, Kyheng M, Labreuche J, de Havenon A, Sibon I, Dargazanli C, Arquizan C, Cognard C, Olivot JM, Anxionnat R, Audibert G, Mazighi M, Blanc R, Lapergue B, Richard S, Gory B, Turjman F, Piotin M, Steglich-Arnholm H, Holtmannspötter M, Taschner C, Eiden S, Haussen D, Boutchakova M, Dorn F, Killer-Oberpfalzer M, Mangiafico S, Psychogios M, Labeyrie M, Biondi A, Bracard S, Grossberg J, Guenego A, Darcourt J, Vukasinovic I, Pomero E, Davies J, Renieri L, Hecker C, Muchada M, Rodesch G, Houdart E, Lockau J, Kastrup A, Redjem H, Behme D, Shallwani H, Christopher M, Mione G, Humbertjean L, Riou-Comte N, Zhu F, Derelle A, Liao L, Piotin M, Redjem H, Escalard S, Maïer B, Desilles J, Ciccio G, Smajda S, Obadia M, Sabben C, Corabianu O, de Broucker T, Smadja D, Alamowitch S, Ille O, Manchon E, Garcia P, Taylor G, Maacha M, Wang A, Evrard S, Tchikviladze M, Ajili N, Weisenburger D, Gorza L, Coskun O, Di Maria F, Rodesh G, Leguen M, Gratieux J, Pico F, Rakotoharinandrasana H, Tassan P, Poll R, Marinier S, Gariel F, Barreau X, Berge J, Veunac L, Menegon P, Lucas L, Olindo S, Renou P, Sagnier S, Poli M, Debruxelles S, Tourdias T, Liegey J, Detraz L, Daumas-Duport B, Alexandre P, Roy M, Lenoble C, L’allinec V, Girot J, Desal H, Bechiri F, Bracard S, Braun M, Derelle A, Tonnelet R, Liao L, Zhu F, Schmitt E, Planel S, Humbertjean L, Mione G, Lacour J, Hossu G, Beaumont M, Bailang M, Reitter M, Masson A, Alb L, Tabarna A, Voicu M, Podar I, Brezeanu M, Guy S, Costalat V, Gascou G, Lefèvre P, Derraz I, Riquelme C, Gaillard N, Mourand I, Corti L. Endovascular Therapy of Anterior Circulation Tandem Occlusions. Stroke 2021, 52: 3097-3105. PMID: 34372671, DOI: 10.1161/strokeaha.120.033032.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnterior Cerebral ArteryArterial Occlusive DiseasesCarotid Artery, InternalCarotid Artery, Internal, DissectionCerebral HemorrhageEndovascular ProceduresFemaleFranceHumansIntracranial ArteriosclerosisIschemic StrokeMaleMiddle AgedPatient SafetyPropensity ScoreRegistriesStentsStrokeThrombectomyTreatment OutcomeConceptsAnterior circulation tandem occlusionTandem occlusion strokeAcute ischemic strokeStent groupEndovascular therapyIntracerebral hemorrhageTandem occlusionsHigher oddsFavorable outcomeIschemic strokeOcclusion strokeTreatment approachesParenchymal hemorrhage type 2Internal carotid artery lesionsPropensity score-adjusted analysisAcute carotid stentingSymptomatic intracerebral hemorrhageCarotid artery lesionsIndividual patient dataBest treatment approachCurrent clinical practiceDifferent treatment approachesHigh rateSuccessful reperfusionAnterior circulationCollateral status reperfusion and outcomes after endovascular therapy: insight from the Endovascular Treatment in Ischemic Stroke (ETIS) Registry
Anadani M, Finitsis S, Clarençon F, Richard S, Marnat G, Bourcier R, Sibon I, Dargazanli C, Arquizan C, Blanc R, Lapergue B, Consoli A, Eugene F, Vannier S, Spelle L, Denier C, Boulanger M, Gauberti M, Liebeskind DS, de Havenon A, Saleme S, Macian F, Rosso C, Naggara O, Turc G, Ozkul-Wermester O, Papagiannaki C, Viguier A, Cognard C, Le Bras A, Evain S, Wolff V, Pop R, Timsit S, Gentric JC, Bourdain F, Veunac L, Maier B, Gory B. Collateral status reperfusion and outcomes after endovascular therapy: insight from the Endovascular Treatment in Ischemic Stroke (ETIS) Registry. Journal Of NeuroInterventional Surgery 2021, 14: 551-557. PMID: 34140288, DOI: 10.1136/neurintsurg-2021-017553.Peer-Reviewed Original ResearchConceptsIschemic Stroke RegistryPoor collateral groupSuccessful reperfusionCollateral statusEndovascular therapyGood collateralsEVT outcomesStroke RegistryCollateral groupEndovascular treatmentFunctional outcomeFavorable outcomeHigher oddsTherapeutic Neuroradiology/SocietyInterventional Radiology guidelinesPoor collateralsPretreatment angiogramsClinical benefitExcellent outcomesRadiology guidelinesReperfusionLower oddsBetter outcomesSignificant interactionOutcomesEndovascular therapy with or without intravenous thrombolysis in acute stroke with tandem occlusion
Anadani M, Marnat G, Consoli A, Papanagiotou P, Nogueira RG, Spiotta AM, Bourcier R, Kyheng M, Labreuche J, Siddiqui AH, Ribo M, de Havenon A, Fischer U, Sibon I, Dargazanli C, Arquizan C, Cognard C, Olivot JM, Anxionnat R, Audibert G, Mazighi M, Blanc R, Lapergue B, Richard S, Gory B, Investigators T. Endovascular therapy with or without intravenous thrombolysis in acute stroke with tandem occlusion. Journal Of NeuroInterventional Surgery 2021, 14: 314-320. PMID: 33911016, DOI: 10.1136/neurintsurg-2020-017202.Peer-Reviewed Original ResearchConceptsCervical internal carotid arteryIntravenous thrombolysisAcute ischemic strokeTandem occlusionsEndovascular therapyInternal carotid arteryFavorable outcomeAcute strokeIschemic strokeCarotid arteryHigher oddsAnterior circulation tandem occlusionAcute tandem occlusionIschemic Stroke RegistrySignificant hemorrhagic complicationsIVT treatmentHemorrhagic complicationsStroke RegistrySuccessful reperfusionRankin ScaleConsecutive patientsIPTW analysisPrimary outcomeEndovascular treatmentPuncture timeDuration of symptomatic stroke and successful reperfusion with endovascular thrombectomy for anterior circulation large vessel occlusive stroke
de Havenon A, Alexander MD, Nogueira RG, Haussen DC, Castonguay AC, Linfante I, Johnson MA, Nguyen TN, Mokin M, Zaidat OO. Duration of symptomatic stroke and successful reperfusion with endovascular thrombectomy for anterior circulation large vessel occlusive stroke. Journal Of NeuroInterventional Surgery 2021, 13: 1128-1131. PMID: 33526478, PMCID: PMC8325713, DOI: 10.1136/neurintsurg-2020-016961.Peer-Reviewed Original ResearchConceptsAcute ischemic stroke patientsIschemic stroke patientsSymptomatic strokeSuccessful reperfusionLogistic regression modelsAcute strokeEndovascular therapyStroke patientsLarge vessel occlusive strokeAnterior circulation occlusionCerebral Infarction scoreReal-world cohortLarge vessel occlusionBalloon guide catheterMiddle cerebral arteryIndividual patient dataInternal carotid arteryProbability of reperfusionLower ratesOcclusive strokeEndovascular thrombectomyMechanical thrombectomySecondary outcomesStroke onsetPrimary outcome
2020
Benefit of endovascular thrombectomy for M2 middle cerebral artery occlusion in the ARISE II study
de Havenon A, Narata AP, Amelot A, Saver JL, Bozorgchami H, Mattle HP, Ribo M, Andersson T, Zaidat OO, investigators A. Benefit of endovascular thrombectomy for M2 middle cerebral artery occlusion in the ARISE II study. Journal Of NeuroInterventional Surgery 2020, 13: 779-783. PMID: 33219148, PMCID: PMC8134506, DOI: 10.1136/neurintsurg-2020-016427.Peer-Reviewed Original ResearchConceptsMiddle cerebral artery occlusionM2 occlusionsCerebral artery occlusionM1 occlusionEndovascular thrombectomyAdverse eventsBetter outcomesArtery occlusionIschemic strokeReperfusion ratesM2-segment middle cerebral artery occlusionM2 middle cerebral artery occlusionsScale scoreHealth Stroke Scale scoreBaseline National InstitutesStroke Scale scoreAcute ischemic strokeMajor adverse eventsRankin Scale scorePaucity of dataLogistic regression modelsII trialSuccessful reperfusionII studyPrespecified analysisThe Effect of Hyperglycemia on Infarct Growth after Reperfusion: An Analysis of the DEFUSE 3 trial
Yaghi S, Dehkharghani S, Raz E, Jayaraman M, Tanweer O, Grory BM, Henninger N, Lansberg MG, Albers GW, Havenon A. The Effect of Hyperglycemia on Infarct Growth after Reperfusion: An Analysis of the DEFUSE 3 trial. Journal Of Stroke And Cerebrovascular Diseases 2020, 30: 105380. PMID: 33166769, PMCID: PMC7736545, DOI: 10.1016/j.jstrokecerebrovasdis.2020.105380.Peer-Reviewed Original ResearchConceptsDEFUSE-3 trialsBaseline glucose levelsInfarct growthGlucose levelsPrimary outcomeAcute ischemic stroke patientsAggressive glycemic controlDEFUSE 3 patientsIschemic core volumePotential neuroprotective benefitsIschemic stroke patientsGood functional outcomeLarge vessel occlusionEffects of hyperglycemiaSuccessful endovascular reperfusionAdmission glucoseInfarction growthEndovascular reperfusionSuccessful reperfusionTICI 2bIschemic strokeNeuroprotective benefitsEndovascular therapyGlycemic controlStroke patients
2019
Blood pressure reduction and outcome after endovascular therapy with successful reperfusion: a multicenter study
Anadani M, Arthur AS, Alawieh A, Orabi Y, Alexandrov A, Goyal N, Psychogios MN, Maier I, Kim JT, Keyrouz SG, de Havenon A, Petersen NH, Pandhi A, Swisher CB, Inamullah O, Liman J, Kodali S, Giles JA, Allen M, Wolfe SQ, Tsivgoulis G, Cagle BA, Oravec CS, Gory B, De Marini P, Kan P, Rahman S, Richard S, Nascimento FA, Spiotta A. Blood pressure reduction and outcome after endovascular therapy with successful reperfusion: a multicenter study. Journal Of NeuroInterventional Surgery 2019, 12: 932-936. PMID: 31806668, PMCID: PMC7998040, DOI: 10.1136/neurintsurg-2019-015561.Peer-Reviewed Original ResearchConceptsSBP reductionSystolic blood pressureSuccessful reperfusionMechanical thrombectomyPoor outcomeSafety outcomesAnterior circulation large vessel occlusionElevated systolic blood pressureModified Rankin Scale scoreBlood pressure reductionComprehensive stroke centerSymptomatic intracerebral hemorrhageAcute ischemic strokeMulticenter retrospective studyRankin Scale scoreLarge vessel occlusionIncomplete reperfusionReperfusion statusSafety endpointIschemic strokeStroke centersBlood pressureComplete reperfusionEndovascular therapyIntracerebral hemorrhage