2024
Sex Modifies the Severity and Outcome of Spontaneous Intracerebral Hemorrhage
Rivier C, Renedo D, Marini S, Magid‐Bernstein J, de Havenon A, Rosand J, Hanley D, Ziai W, Mayer S, Woo D, Sansing L, Sheth K, Anderson C, Falcone G. Sex Modifies the Severity and Outcome of Spontaneous Intracerebral Hemorrhage. Annals Of Neurology 2024 PMID: 39499118, DOI: 10.1002/ana.27123.Peer-Reviewed Original ResearchRisk of hematoma expansionHighest risk of hematoma expansionRisk of poor outcomesIntracerebral hemorrhageHematoma expansionHigh riskMale sexPoor outcomeOutcome of spontaneous intracerebral hemorrhageClinical characteristics of patientsStudies of intracerebral hemorrhageNon-traumatic intracerebral hemorrhageIndividual patient data meta-analysisPatient data meta-analysisSpontaneous intracerebral hemorrhageSingle-center studyIntracerebral hemorrhage patientsHigh risk of expansionCharacteristics of patientsIntracerebral hemorrhage severityPoor functional outcomeRandomized clinical trialsData meta-analysisHemorrhage volumeClinical characteristics2024 AHA/ASA Performance and Quality Measures for Spontaneous Intracerebral Hemorrhage: A Report From the American Heart Association/American Stroke Association
Ruff I, de Havenon A, Bergman D, Dugue R, Frontera J, Goldstein J, Hemphill J, Marulanda-Londono E, Prabhakaran S, Richards C, Sunmonu N, Vilar P, Wolfe S. 2024 AHA/ASA Performance and Quality Measures for Spontaneous Intracerebral Hemorrhage: A Report From the American Heart Association/American Stroke Association. Stroke 2024, 55: e199-e230. PMID: 38695183, DOI: 10.1161/str.0000000000000464.Peer-Reviewed Original ResearchAmerican Heart Association/American Stroke AssociationStroke AssociationQuality measuresPosthospital settingPatient careStroke expertsData collectionWorking GroupPerformance measuresSpontaneous intracerebral hemorrhageAmericanGuidelinesIntracerebral hemorrhageAssociationPrehospitalCareAHA/ASAPotential challengesIntervention
2022
409 Impact of COVID-19 on the Hospitalization, Treatment, and Outcomes of Intracerebral Hemorrhage and Subarachnoid Hemorrhage in the United States
Ravindra V, Grandhi R, de Havenon A. 409 Impact of COVID-19 on the Hospitalization, Treatment, and Outcomes of Intracerebral Hemorrhage and Subarachnoid Hemorrhage in the United States. Neurosurgery 2022, 68: 94-95. DOI: 10.1227/neu.0000000000001880_409.Peer-Reviewed Original ResearchAdjusted odds ratioHospital death rateIntensive care stayIntracerebral hemorrhageFavorable dischargeIntracranial hemorrhageSubarachnoid hemorrhageCOVID-19Vizient Clinical Data BaseDeath rateLonger hospital lengthOnly small cohortsLonger hospital stayIntensive care lengthLength of hospitalOutcome of deathCohort of patientsSpontaneous intracerebral hemorrhageClinical data baseICH controlsHospital deathHospital lengthHospital stayControl patientsSecondary outcomes
2021
Intracranial Pressure and Cerebral Perfusion Pressure in Large Spontaneous Intracranial Hemorrhage and Impact of Minimally Invasive Surgery
Al-Kawaz MN, Li Y, Thompson RE, Avadhani R, de Havenon A, Gruber J, Awad I, Hanley DF, Ziai W. Intracranial Pressure and Cerebral Perfusion Pressure in Large Spontaneous Intracranial Hemorrhage and Impact of Minimally Invasive Surgery. Frontiers In Neurology 2021, 12: 729831. PMID: 34512537, PMCID: PMC8427275, DOI: 10.3389/fneur.2021.729831.Peer-Reviewed Original ResearchCerebral perfusion pressureLong-term mortalityHigh intracranial pressureIntracranial pressureCPP readingsTerm mortalityPerfusion pressureIntracerebral hemorrhageMIS groupControl groupLarge Spontaneous Intracerebral HemorrhageICP readingsInvasive surgeryHematoma volume reductionBlinded outcome assessmentShort-term mortalitySpontaneous intracerebral hemorrhageSpontaneous intracranial hemorrhageMultiple logistic regressionMIS patientsMISTIE IIISecondary outcomesPrimary outcomeHigher proportionIntracranial hemorrhageImpact of COVID-19 on the hospitalization, treatment, and outcomes of intracerebral and subarachnoid hemorrhage in the United States
Ravindra VM, Grandhi R, Delic A, Hohmann S, Shippey E, Tirschwell D, Frontera JA, Yaghi S, Majersik JJ, Anadani M, de Havenon A. Impact of COVID-19 on the hospitalization, treatment, and outcomes of intracerebral and subarachnoid hemorrhage in the United States. PLOS ONE 2021, 16: e0248728. PMID: 33852591, PMCID: PMC8046225, DOI: 10.1371/journal.pone.0248728.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCerebral HemorrhageChildChild, PreschoolCohort StudiesCOVID-19EthnicityFemaleHospital MortalityHospitalizationHumansInfantLength of StayMaleMiddle AgedMinority GroupsPatient DischargeRetrospective StudiesSARS-CoV-2Subarachnoid HemorrhageTreatment OutcomeUnited StatesConceptsAdjusted odds ratioHospital death rateIntensive care stayOutcome of deathIntracerebral hemorrhageSubarachnoid hemorrhageFavorable dischargeCOVID-19Vizient Clinical Data BaseDeath rateLonger hospital lengthIntensive care lengthLength of hospitalLonger hospital stayCohort of patientsMixed-effects logistic regression modelSpontaneous intracerebral hemorrhageCOVID-19 infectionClinical data baseLogistic regression modelsICH controlsHospital deathHospital stayHospital lengthSecondary outcomes