2021
A systematic review of ketamine for the treatment of depression among older adults
Farheen S, Gupta A, Dhar R, Patadia P, Funaro M, Bhattacharya G, Tampi R. A systematic review of ketamine for the treatment of depression among older adults. American Journal Of Geriatric Psychiatry 2021, 29: s93-s96. DOI: 10.1016/j.jagp.2021.01.089.Peer-Reviewed Educational MaterialsPrimary outcome measureUse of ketamineLate-life depressionTreatment of depressionOlder adultsElectroconvulsive therapyReceptor antagonistLife depressionOutcome measuresCurrent evidenceDepressive symptomsOlder subjectsHamilton Depression Rating Scale scoresN-methyl-D-aspartate receptor antagonistSystematic reviewStudy participantsDepression Rating Scale scoresAdverse effectsBenefits of ketamineTolerability of ketamineCognitive adverse effectsCochrane Central RegisterTreatment-resistant depressionAnti-depressant effectsRelapse of symptomsIs there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults?
Bhattacharya G, Gupta A, Joshi P, Lehman M, Funaro M, Tampi D, Tampi R. Is there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults? American Journal Of Geriatric Psychiatry 2021, 29: s136-s139. DOI: 10.1016/j.jagp.2021.01.131.Peer-Reviewed Educational MaterialsTreatment of deliriumRandomized control trialTotal knee replacementTotal hip replacementValproic acid preparationsPostoperative deliriumValproic acid derivativesPerioperative useSpinal surgeryOlder adultsCurrent evidenceElective total knee replacementElective total hip replacementAverage medical care costAcute neuropsychiatric syndromeCauses of deliriumUse of gabapentinManagement of deliriumNon-pharmacological strategiesCochrane Central RegisterNon-pharmacologic treatmentsHospitalized older adultsUse of anticonvulsantsIntensive care unitPalliative care setting
2020
Systematic review of benzodiazepines for anxiety disorders in late life.
Gupta A, Bhattacharya G, Farheen SA, Funaro M, Balasubramaniam M, Young J, Tampi DJ, Tampi RR. Systematic review of benzodiazepines for anxiety disorders in late life. Annals Of Clinical Psychiatry 2020, 32: 114-127. PMID: 32343283.Peer-Reviewed Educational MaterialsConceptsAnxiety disordersSystematic reviewOlder adultsTolerability of benzodiazepinesCochrane Central RegisterMild adverse effectsLater lifeEnglish-language articlesTreatment of anxietyLong-term useWeb of ScienceTolerability dataCentral RegisterControlled TrialsCochrane DatabaseOvid EmbaseLong-term benefitsOvid MEDLINEInclusion criteriaEligible articlesBenzodiazepinesDecreased anxietyStudy periodAdverse effectsTrials
2019
Antidepressants for anxiety disorders in late-life: A systematic review.
Balasubramaniam M, Joshi P, Alag P, Gupta S, Maher S, Tampi D, Gupta A, Young J, Tampi RR. Antidepressants for anxiety disorders in late-life: A systematic review. Annals Of Clinical Psychiatry 2019, 31: 277-291. PMID: 31369663.Peer-Reviewed Educational MaterialsConceptsLate-life anxietyAnxiety disordersRCTs of antidepressantsCochrane Central RegisterTolerability of antidepressantsBibliographic databases PubMedGeneralized anxiety disorderLong-term useCentral RegisterControlled TrialsAntidepressantsElectronic searchDatabases PubMedSystematic reviewOlder adultsStudy periodTrialsDisordersAnxiety symptomsLater lifeLimited dataSignificant reductionAnxietyReviewTolerability