Taylor J. Keding, PhD
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About
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Associate Research Scientist
Biography
Taylor is an associate research scientist with Yale's Department of Psychology, working with Dr. Dylan Gee and the Clinical Affective Neuroscience & Development Lab. He has a joint appointment with the University of Wisconsin-Madison Department of Psychiatry, working with Dr. Ryan Herringa and the BRAVE Research Center. He received his Ph.D. in Neuroscience from the University of Wisconsin-Madison . His research broadly focuses on the development of emotion-related brain circuitry during childhood and adolescence, how circuit maturation is altered by early-life adversity, and how these alterations influence risk for pediatric psychopathology. His work utilizes neuroimaging (sMRI, fMRI, DTI), in combination with computational and predictive modeling approaches. In recognition of his work, Taylor has received numerous awards and honors from organizations such as the National Institutes of Mental Health, the National Science Foundation, the Brain and Behavior Research Foundation, the International Society for Traumatic Stress Studies, the Society for Biological Psychiatry, and the American College of Neuropsychopharmacology.
Appointments
Department of Psychology
Associate Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- University of Wisconsin-Madison, Neuroscience (2021)
- BSc
- University of Wisconsin-Madison, Neurobiology (2014)
- BSc
- University of Wisconsin-Madison, Psychology (2014)
Research
Overview
Medical Research Interests
ORCID
0000-0002-0507-6712- View Lab Website
Clinical Affective Neuroscience & Development Lab
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Dylan Gee, PhD
Bailey Holt-Gosselin
Jutta Joormann
Carla E Marin, PhD
Eli Lebowitz, PhD
Wendy Silverman, PhD, ABPP
Brain
Child Development
Publications
Featured Publications
Neural Circuit Markers of Familial Risk for Depression Among Healthy Youths in the Adolescent Brain Cognitive Development Study
Holt-Gosselin B, Keding T, Poulin R, Brieant A, Rueter A, Hendrickson T, Perrone A, Byington N, Houghton A, Miranda-Dominguez O, Feczko E, Fair D, Joormann J, Gee D. Neural Circuit Markers of Familial Risk for Depression Among Healthy Youths in the Adolescent Brain Cognitive Development Study. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2023, 9: 185-195. PMID: 37182734, PMCID: PMC10640659, DOI: 10.1016/j.bpsc.2023.05.001.Peer-Reviewed Original ResearchCitationsAltmetricConceptsFamilial riskHR youthLR youthHealthy youthWhole-brain seedEarly-onset depressionResting-state FCYears of ageBrain-based markersFunctional connectivity patternsHigh familial riskCognitive Development StudyAdolescent Brain Cognitive Development (ABCD) studyMaternal riskLow familial riskMaternal historyFamily historyStriatal connectivityMaternal depressionDepression riskNucleus accumbensPsychiatric problemsNeural circuitsEarly detectionSmall sample sizeViolence Exposure and Amygdala-Prefrontal Circuit Maturation: Developmental Markers of Psychiatric Risk in Youth
Keding T, Herringa R. Violence Exposure and Amygdala-Prefrontal Circuit Maturation: Developmental Markers of Psychiatric Risk in Youth. Biological Psychiatry 2022, 91: s47-s48. DOI: 10.1016/j.biopsych.2022.02.140.Peer-Reviewed Original ResearchCitationsAltmetricDifferential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology
Keding T, Heyn S, Russell J, Zhu X, Cisler J, McLaughlin K, Herringa R. Differential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology. American Journal Of Psychiatry 2021, 178: 1026-1036. PMID: 34407623, PMCID: PMC8570983, DOI: 10.1176/appi.ajp.2021.20081192.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsChildhood abusePhysical neglectBrain Age Gap EstimationNormative brain developmentCircuit maturationBrain-wide patternsChildhood physical neglectEarly life adversityFronto-parietal cortexEmotion circuitsThreat generalizationGray matter volumePresence of psychopathologyResilient girlsLateral prefrontalHyperarousal symptomsInternalizing psychopathologyNeural contributorsAbused girlsInternalizing disorder diagnosesInternalizing diagnosesMaltreatment historyAbuse exposureAbuse historyNeurodevelopmental markersChildhood exposure to interpersonal violence is associated with greater transdiagnostic integration of psychiatric symptoms
Russell JD, Keding TJ, He Q, Li JJ, Herringa RJ. Childhood exposure to interpersonal violence is associated with greater transdiagnostic integration of psychiatric symptoms. Psychological Medicine 2020, 52: 1883-1891. PMID: 33161911, PMCID: PMC8106688, DOI: 10.1017/s0033291720003712.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsChildhood exposureIPV exposureTreatment-resistant populationStructured Clinical InterviewGreater psychiatric comorbidityMental health symptomsPotential clinical implicationsInterpersonal violencePopulation-representative sampleBridge symptomsPsychiatric comorbidityViolence-exposed youthPsychiatric symptomsTreatment resistanceSymptom communitiesClinical InterviewHealth symptomsMental illnessClinical implicationsSymptomsSymptom associationMultiple disordersViolence exposureDiagnostic statusPatterns of association
2024
4.6 Examining Familial Risk of Depression and Family Conflict in the Prediction of Psychopathology in the ABCD Study
Basol E, Holt-Gosselin B, Joormann J, Gee D, Rodrigues K, Keding T. 4.6 Examining Familial Risk of Depression and Family Conflict in the Prediction of Psychopathology in the ABCD Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 2024, 63: s232. DOI: 10.1016/j.jaac.2024.08.251.Peer-Reviewed Original ResearchDiverging Effects of Violence Exposure and Psychiatric Symptoms on Amygdala-Prefrontal Maturation during Childhood and Adolescence
Keding T, Russell J, Zhu X, He Q, Li J, Herringa R. Diverging Effects of Violence Exposure and Psychiatric Symptoms on Amygdala-Prefrontal Maturation during Childhood and Adolescence. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2024 PMID: 39182725, DOI: 10.1016/j.bpsc.2024.08.003.Peer-Reviewed Original ResearchConceptsBasolateral amygdalaFunctional connectivityPsychiatric symptomsViolence exposureCircuit maturationOrbitofrontal cortex functional connectivityDevelopment of psychiatric symptomsResting-state functional connectivityEffects of violence exposureAmygdala-prefrontal cortexSeverity of psychopathologyBrain age gap estimationIncreased psychiatric symptomsPhiladelphia Neurodevelopmental CohortThreat appraisal processEffects of adversityExposure to violenceNeurobiological correlatesAssociated with delayed maturationBrain circuitryNeurodevelopmental mechanismsPsychiatric riskIndividual differencesNeurodevelopmental CohortAtypical neurodevelopmentFamilial risk for depression moderates neural circuitry in healthy preadolescents to predict adolescent depression symptoms in the Adolescent Brain Cognitive Development (ABCD) Study
Holt-Gosselin B, Keding T, Rodrigues K, Rueter A, Hendrickson T, Perrone A, Byington N, Houghton A, Miranda-Dominguez O, Feczko E, Fair D, Joormann J, Gee D. Familial risk for depression moderates neural circuitry in healthy preadolescents to predict adolescent depression symptoms in the Adolescent Brain Cognitive Development (ABCD) Study. Developmental Cognitive Neuroscience 2024, 68: 101400. PMID: 38870601, PMCID: PMC11225685, DOI: 10.1016/j.dcn.2024.101400.Peer-Reviewed Original ResearchAltmetricConceptsAdolescent Brain Cognitive DevelopmentAdolescent depressive symptomsDepressive symptomsFamilial riskFunctional connectivityResting-state FC patternsCognitive developmentFamily history of depressionAdolescent-onset depressionLow familial riskHistory of depressionElevated familial riskMixed-effects regression analysisNucleus accumbensStriatal FCLR youthHR youthSensory/somatomotor networkFC patternsNeural circuitryNeural markersDepression riskDepressionPreadolescentsLongitudinal studyChanges in Frontoamygdala Circuitry Associated With a Parent-Focused Intervention for Pediatric Anxiety Disorders
Gee D, Gunther K, Petrie D, Kitt E, Keding T, Broussard A, Zacharek S, Nardini C, Hommel G, Martino A, Anderson T, Spencer H, Odriozola P, Marin C, Silverman W, Lebowitz E. Changes in Frontoamygdala Circuitry Associated With a Parent-Focused Intervention for Pediatric Anxiety Disorders. Biological Psychiatry 2024, 95: s44. DOI: 10.1016/j.biopsych.2024.02.110.Peer-Reviewed Original ResearchParent Psychopathology and Behavioral Effects on Child Brain–Symptom Networks in the ABCD Study
George G, Heyn S, Russell J, Keding T, Herringa R. Parent Psychopathology and Behavioral Effects on Child Brain–Symptom Networks in the ABCD Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 2024, 63: 1024-1034. PMID: 38522613, PMCID: PMC11416563, DOI: 10.1016/j.jaac.2023.12.016.Peer-Reviewed Original ResearchCitationsAltmetricConceptsParental psychopathologyChild psychopathologyParenting behaviorsDevelopment of child psychopathologyEffects of parental psychopathologyIntergenerational transmission of psychopathologyTransmission of psychopathologyChild Behavior ChecklistParents' psychopathological symptomsResting-state fMRIPsychopathological symptomsBehavioral effectsBehavior ChecklistPsychopathologyABCD studyBrain connectivityChildren neuroimagingIntergenerational transmissionChildrenParentsFMRINeuroimagingBehaviorAdolescentsSignificant correlationLeveraging multivariate approaches to advance the science of early-life adversity
Brieant A, Sisk L, Keding T, Cohodes E, Gee D. Leveraging multivariate approaches to advance the science of early-life adversity. Child Abuse & Neglect 2024, 106754. PMID: 38521731, PMCID: PMC11416566, DOI: 10.1016/j.chiabu.2024.106754.Peer-Reviewed Original ResearchCitationsAltmetric