Anne Spichler Moffarah, MD, PhD
Assistant ProfessorCards
About
Research
Publications
2025
An Extraordinary Case of Prosthetic Joint Infection by Listeria monocytogenes and Histoplasma capsulatum.
Luu T, Daddi L, Azar M, Trubin P, Molloy I, Spichler-Moffarah A. An Extraordinary Case of Prosthetic Joint Infection by Listeria monocytogenes and Histoplasma capsulatum. Cureus 2025, 17: e76901. PMID: 39906453, DOI: 10.7759/cureus.76901.Peer-Reviewed Case Reports and Technical Notes
2024
Retinal integrity in human babesiosis: a pilot study
Dionne E, Adelman R, Cekic O, Golden M, Moffarah A, Krause P, Farhadian S. Retinal integrity in human babesiosis: a pilot study. BMC Ophthalmology 2024, 24: 310. PMID: 39048971, PMCID: PMC11267664, DOI: 10.1186/s12886-024-03568-6.Peer-Reviewed Original ResearchConceptsEvidence of retinopathyNo study patientRetina of patientsCohort of patientsAbnormal vessel formationComplication of babesiosisRetinal tearsRetinal inflammationRetinal eye examResultsTen patientsRetinal integrityRetinal examinationRetinal bleedingIndirect ophthalmoscopeRetinal abnormalitiesStudy patientsChart reviewCase reportEye examPilot studyPatientsAnimal studiesSmall studyClinical informationHuman babesiosis
2023
Neurologic Complications of Babesiosis, United States, 2011–2021 - Volume 29, Number 6—June 2023 - Emerging Infectious Diseases journal - CDC
Locke S, O’Bryan J, Zubair A, Rethana M, Moffarah A, Krause P, Farhadian S. Neurologic Complications of Babesiosis, United States, 2011–2021 - Volume 29, Number 6—June 2023 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2023, 29: 1127-1135. PMID: 37209667, PMCID: PMC10202888, DOI: 10.3201/eid2906.221890.Peer-Reviewed Original ResearchConceptsNeurologic complicationsNeurologic symptomsRisk factorsYale-New Haven HospitalInfectious Diseases journal - CDCHigh-grade parasitemiaNeurologic risk factorsRange of symptomsAdult patientsRenal failureDiabetes mellitusFrequent symptomsHospital admissionImpaired consciousnessMedical recordsEndemic areasParasitic infectionsPatientsSymptomsIntraerythrocytic protozoaComplicationsBabesiosisNew HavenDeliriumMellitusThe impact of ABO and RhD blood types on Babesia microti infection
Jajosky R, O’Bryan J, Spichler-Moffarah A, Jajosky P, Krause P, Tonnetti L. The impact of ABO and RhD blood types on Babesia microti infection. PLOS Neglected Tropical Diseases 2023, 17: e0011060. PMID: 36696414, PMCID: PMC9901808, DOI: 10.1371/journal.pntd.0011060.Peer-Reviewed Original ResearchConceptsB. microti infectionABO blood typeBabesia microti infectionMicroti infectionBlood donorsBlood typeDisease severityPlasmodium falciparum malaria patientsFalciparum malaria patientsHigher peak parasitemiaRed blood cell antigensType BImpact of ABOBlood cell antigensBlood type BMalaria patientsTransfusion strategyInfected donorsRhD blood typeSevere diseasePeak parasitemiaB antigensCell antigensPossible associationRhD antigen
2022
Prosthetic Joint Infections of the Hip and Knee Among the Elderly: A Retrospective Study
Spichler-Moffarah A, Rubin LE, Bernstein JA, O'Bryan J, McDonald E, Golden M. Prosthetic Joint Infections of the Hip and Knee Among the Elderly: A Retrospective Study. The American Journal Of Medicine 2022, 136: 100-107. PMID: 36063860, DOI: 10.1016/j.amjmed.2022.08.006.Peer-Reviewed Original ResearchConceptsProsthetic joint infectionJoint infectionTotal joint arthroplasty increasesMortality of patientsTertiary medical centerPeriprosthetic joint infectionYears of ageClinical characteristicsOlder patientsGeriatric populationArthroplasty increasesRisk factorsMedical CenterPopulation agesPatientsInfectionMortalityAgeEtiologyHipPrevalenceKneeCardiac Complications of Human Babesiosis
Spichler-Moffarah A, Ong E, O’Bryan J, Krause PJ. Cardiac Complications of Human Babesiosis. Clinical Infectious Diseases 2022, 76: e1385-e1391. PMID: 35983604, PMCID: PMC10169432, DOI: 10.1093/cid/ciac525.Peer-Reviewed Original ResearchConceptsYale-New Haven HospitalCardiac complicationsRisk factorsIntensive care unit stayCardiovascular disease risk factorsHuman babesiosisCommon cardiac complicationHigh-grade parasitemiaLife-threatening complicationsDisease risk factorsLonger median lengthQT interval prolongationHigh mortality rateUnit stayComplication groupTick-borne diseaseAdult patientsCardiac outcomesMost patientsThin blood smearsHeart failureInterval prolongationModerate illnessRecord reviewAtrial fibrillationUnnecessary Routine Use of Mycobacterial Cultures in Patients With Periprosthetic Joint Infections
Golden M, Moffarah AS, Kerantzas C, Rubin L, O’Bryan J. Unnecessary Routine Use of Mycobacterial Cultures in Patients With Periprosthetic Joint Infections. Open Forum Infectious Diseases 2022, 9: ofac132. PMID: 35392456, PMCID: PMC8982768, DOI: 10.1093/ofid/ofac132.Peer-Reviewed Original ResearchLegionella pneumophila and Staphylococcus aureus co-infections in a patient with SARS-CoV-2
Sanchez A, Elliott EI, Wang P, Spichler-Moffarah A. Legionella pneumophila and Staphylococcus aureus co-infections in a patient with SARS-CoV-2. BMJ Case Reports 2022, 15: e248536. PMID: 35232746, PMCID: PMC8889248, DOI: 10.1136/bcr-2021-248536.Peer-Reviewed Original ResearchConceptsCOVID-19 therapySARS-CoV-2Positive SARS-CoV-2 testSARS-CoV-2 testAcute febrile illnessCommunity-acquired pneumoniaSevere COVID-19Patient's successful recoveryCOVID-19COVID-19 managementSecond bacterial infectionMRSA pneumoniaFebrile illnessRespiratory symptomsInitial presentationHigh suspicionLobar pneumoniaWorse outcomesPositive testPatientsBacterial infectionsPneumoniaSuccessful recoveryLegionnaires' diseaseSerogroup 1
2021
A new positive SARS-CoV-2 test months after severe COVID-19 illness: reinfection or intermittent viral shedding?
Tuan J, Spichler-Moffarah A, Ogbuagu O. A new positive SARS-CoV-2 test months after severe COVID-19 illness: reinfection or intermittent viral shedding? BMJ Case Reports 2021, 14: e240531. PMID: 33542020, PMCID: PMC8098910, DOI: 10.1136/bcr-2020-240531.Peer-Reviewed Case Reports and Technical NotesConceptsSARS-CoV-2 RNA testSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2SARS-CoV-2 reinfectionSevere COVID-19 illnessRespiratory syndrome coronavirus 2COVID-19 reinfectionLong asymptomatic periodCOVID-19 illnessSyndrome coronavirus 2Intermittent viral sheddingAsymptomatic periodViral sheddingRNA testCoronavirus 2Clinical managementPersistent infectionDisease 4Molecular testingReinfectionRNA PCRCurrent presentationPotential casesMonthsPatientsDiagnosis of Pneumonia Due to Invasive Molds
Foppiano Palacios C, Spichler Moffarah A. Diagnosis of Pneumonia Due to Invasive Molds. Diagnostics. 2021; 11(7):1226.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Clinical Care
Overview
Anne Spichler Moffarah, MD, PhD, specializes in infectious diseases and cares for patients with cellulitis, bacterial endocarditis, brain/liver/lung abscesses, UTI/ prosthetic joint infection, fracture related infections, bone and joint infections, fever of unknown origin, babesiosis, tropical disease,
Dr. Spichler Moffarah's research interests include prosthetic joint infections, bone and joint infections, implant related infections, as well as babesiosis and Leptopsirosis.
Dr. Spichler Moffarah is an assistant professor at Yale School of Medicine.
Clinical Specialties
Infectious Diseases
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Sepsis
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Board Certifications
Infectious Disease
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2019
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2017
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