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Unique Immune Profile Identified in Fibrotic Hypersensitivity Pneumonitis
Fibrotic hypersensitivity pneumonitis is a chronic and progressive interstitial lung disease, caused by an immune response to inhaled foreign antigens or allergens. Researchers from Yale’s Section of Pulmonary, Critical Care and Sleep Medicine have used single-cell sequencing technology to provide the first high-resolution atlas of this disease, revealing a previously unrecognized immune signature. Their findings were recently published in the American Journal of Respiratory and Critical Care Medicine.