2011
Abnormal prefrontal activity subserving attentional control of emotion in remitted depressed patients during a working memory task with emotional distracters
Kerestes R, Ladouceur CD, Meda S, Nathan PJ, Blumberg HP, Maloney K, Ruf B, Saricicek A, Pearlson GD, Bhagwagar Z, Phillips ML. Abnormal prefrontal activity subserving attentional control of emotion in remitted depressed patients during a working memory task with emotional distracters. Psychological Medicine 2011, 42: 29-40. PMID: 21733287, DOI: 10.1017/s0033291711001097.Peer-Reviewed Original ResearchConceptsVentrolateral prefrontal cortexNegative emotional informationFunctional magnetic resonance imagingEmotional distractersAttentional controlEmotional informationMemory taskMemory loadEmotional Face N-Back (EFNBACK) taskOrbitofrontal cortexNegative emotional distractersN-back taskInterface of cognitionAccurate task performanceKey neural circuitsBlood oxygen level-dependent functional magnetic resonance imagingRMDD patientsLevel-dependent functional magnetic resonance imagingAttentional biasesFacial emotionsEmotion processingDepressed patientsDistracter stimuliTrait-like abnormalitiesRight DLPFC
2002
Acute administration of citalopram facilitates memory consolidation in healthy volunteers
Harmer C, Bhagwagar Z, Cowen P, Goodwin G. Acute administration of citalopram facilitates memory consolidation in healthy volunteers. Psychopharmacology 2002, 163: 106-110. PMID: 12185407, DOI: 10.1007/s00213-002-1151-x.Peer-Reviewed Original ResearchConceptsMemory consolidationCognitive actionsLong-term memory performanceAuditory Verbal Learning TestRecall/recognitionVerbal Learning TestVerbal memory testsSustained attention performanceFacilitate memory consolidationAttention performanceMemory testImmediate recallLearning TestMemory performanceCognitive functionMemory deficitsInformation processingGroups of subjectsSerotonergic neurotransmissionGroup designRecallNon-specific increaseSuccessful pharmacological treatmentDepressed patientsSymptom improvement