Toral Surti, MD, PhD
Associate Professor of PsychiatryDownloadHi-Res Photo
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Psychiatry
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Associate Professor of Psychiatry
Appointments
Psychiatry
Associate Professor on TermPrimary
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Education & Training
- Research Fellowship
- Yale University School of Medicine and VA Connecticut Healthcare System (2014)
- Research Fellowship
- Yale University School of Medicine (2012)
- Residency
- Yale University School of Medicine (2011)
- PhD
- University of California at San Francisco (2007)
- MD
- University of California at San Francisco (2007)
- BS
- Yale College, Molecular Biophysics and Biochemistry (1998)
Research
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Overview
Medical Research Interests
Cognition; Schizophrenia; Schizophrenia Spectrum and Other Psychotic Disorders; Sleep
ORCID
0000-0002-8497-2629
Research at a Glance
Yale Co-Authors
Frequent collaborators of Toral Surti's published research.
Publications Timeline
A big-picture view of Toral Surti's research output by year.
Research Interests
Research topics Toral Surti is interested in exploring.
Deepak Cyril Dsouza, MBBS, MD
John Krystal, MD
Geena Fram
Nicole Popp Santamauro, MA
Ralitza Gueorguieva, PhD
Anahita Bassir Nia, MD
12Publications
256Citations
Schizophrenia
Publications
2025
A translational neuroscience & computational evaluation of a D1R partial agonist for schizophrenia (TRANSCENDS): Rationale and study design of a brain-based clinical trial
Fonteneau C, Tamayo Z, Price A, Pan L, Afriyie-Agyemang Y, Agrawal S, Butler A, Cail C, Calkins M, Chakilam A, Forselius-Bielen K, Fram G, Frazier A, Gil R, Govil P, Gray D, Grinband J, Gur R, Haubold N, Heffernan Z, Heneks M, Kegeles L, Kohler C, Lin C, Lu J, Mayer M, Pham P, Perlman G, Rahmati M, Ranganathan M, Santamauro N, Schutte C, Selloni A, Van Snellenberg J, Surti T, Wolf D, Zharyy C, Group T, Abi-Dargham A, Gur R, Lieberman J, Kantrowitz J, Anticevic A, Cho Y, Krystal J. A translational neuroscience & computational evaluation of a D1R partial agonist for schizophrenia (TRANSCENDS): Rationale and study design of a brain-based clinical trial. Journal Of Psychiatric Research 2025, 194: 196-210. PMID: 41519104, PMCID: PMC13138834, DOI: 10.1016/j.jpsychires.2025.12.020.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitations
2024
Sleep apnea in schizophrenia: Estimating prevalence and impact on cognition
Ghazikhanian S, Surti T. Sleep apnea in schizophrenia: Estimating prevalence and impact on cognition. Journal Of Psychiatric Research 2024, 177: 330-337. PMID: 39068777, DOI: 10.1016/j.jpsychires.2024.07.028.Peer-Reviewed Original ResearchCitationsPsychotic Disorders and Schizophrenia
Surti T. Psychotic Disorders and Schizophrenia. 2024, 147-157. DOI: 10.1016/b978-0-323-95702-1.00074-9.Peer-Reviewed Original ResearchCitations
2023
Snoozing on Pot: Cannabis and Sleep
Skosnik P, Surti T. Snoozing on Pot: Cannabis and Sleep. 2023, 333-345. DOI: 10.1017/9781108943246.032.BooksRandomized controlled trial of the glycine transporter 1 inhibitor PF-03463275 to enhance cognitive training and neuroplasticity in schizophrenia
Surti T, Ranganathan M, Johannesen J, Gueorguieva R, Deaso E, Kenney J, Krystal J, D'Souza D. Randomized controlled trial of the glycine transporter 1 inhibitor PF-03463275 to enhance cognitive training and neuroplasticity in schizophrenia. Schizophrenia Research 2023, 256: 36-43. PMID: 37141764, PMCID: PMC10257994, DOI: 10.1016/j.schres.2023.04.010.Peer-Reviewed Original ResearchCitationsAltmetric
2022
Eulerian Phase-based Motion Magnification for High-Fidelity Vital Sign Estimation with Radar in Clinical Settings
Oshim F, Surti T, Goldfine C, Carreiro S, Ganesan D, Jayasuriya S, Rahman T. Eulerian Phase-based Motion Magnification for High-Fidelity Vital Sign Estimation with Radar in Clinical Settings. 2022, 00: 1-4. DOI: 10.1109/sensors52175.2022.9967051.Peer-Reviewed Original ResearchCitationsIllness Phase as a Key Assessment and Intervention Window for Psychosis
Kohler C, Wolf D, Abi-Dargham A, Anticevic A, Cho Y, Fonteneau C, Gil R, Girgis R, Gray D, Grinband J, Javitch J, Kantrowitz J, Krystal J, Lieberman J, Murray J, Ranganathan M, Santamauro N, Van Snellenberg J, Tamayo Z, Group T, D'Souza D, Srihari V, Gueorguieva R, Patel P, Forselius-Bielen K, Lu J, Butler A, Fram G, Afriyie-Agyemang Y, Selloni A, Cadavid L, Gomez-Luna S, Gupta A, Radhakrishnan R, Rashid A, Aker R, Abrahim P, Nia A, Surti T, Kegeles L, Carlson M, Goldberg T, Gangwisch J, Benedict E, Govil P, Brazis S, Mayer M, de la Garrigue N, Fallon N, Baumvoll T, Abeykoon S, Perlman G, Bobchin K, Elliott M, Schmidt L, Rush S, Port A, Heffernan Z, Laney N, Kantor J, Hohing T, Gur R, Gur R, Calkins M. Illness Phase as a Key Assessment and Intervention Window for Psychosis. Biological Psychiatry Global Open Science 2022, 3: 340-350. PMID: 37519466, PMCID: PMC10382701, DOI: 10.1016/j.bpsgos.2022.05.009.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitations
2021
Dopamine D1R Receptor Stimulation as a Mechanistic Pro-cognitive Target for Schizophrenia
Abi-Dargham A, Javitch JA, Slifstein M, Anticevic A, Calkins ME, Cho YT, Fonteneau C, Gil R, Girgis R, Gur RE, Gur RC, Grinband J, Kantrowitz J, Kohler C, Krystal J, Murray J, Ranganathan M, Santamauro N, Van Snellenberg J, Tamayo Z, Wolf D, D’Souza D, Srihari V, Gueorguieva R, Patel P, Forselius-Bielen K, Lu J, Butler A, Fram G, Afriyie-Agyemang Y, Selloni A, Cadavid L, Gomez-Luna S, Gupta A, Radhakrishnan R, Rashid A, Aker R, Abrahim P, Nia A, Surti T, Kegeles L, Carlson M, Goldberg T, Gangwisch J, Benedict E, Govil P, Brazis S, Mayer M, de la Garrigue N, Fallon N, Baumvoll T, Abeykoon S, Perlman G, Bobchin K, Elliott M, Schmidt L, Rush S, Port A, Heffernan Z, Laney N, Kantor J, Hohing T, Gray D, Lieberman J. Dopamine D1R Receptor Stimulation as a Mechanistic Pro-cognitive Target for Schizophrenia. Schizophrenia Bulletin 2021, 48: 199-210. PMID: 34423843, PMCID: PMC8781338, DOI: 10.1093/schbul/sbab095.Peer-Reviewed Original ResearchCitationsAltmetric
2015
Rapid Changes in Cannabinoid 1 Receptor Availability in Cannabis-Dependent Male Subjects After Abstinence From Cannabis.
D'Souza D, Cortes-Briones J, Ranganathan M, Thurnauer H, Creatura G, Surti T, Planeta B, Neumeister A, Pittman B, Normandin M, Kapinos M, Ropchan J, Huang Y, Carson R, Skosnik P. Rapid Changes in Cannabinoid 1 Receptor Availability in Cannabis-Dependent Male Subjects After Abstinence From Cannabis. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2015, 1: 60-67. PMID: 29560896, DOI: 10.1016/j.bpsc.2015.09.008.Peer-Reviewed Original ResearchCitationsAltmetric
2001
Approaches to solving the rigid receptor problem by identifying a minimal set of flexible residues during ligand docking11PDB coordinates have been deposited with the RSCB with accession ID: 1F28.
Anderson A, O’Neil R, Surti T, Stroud R. Approaches to solving the rigid receptor problem by identifying a minimal set of flexible residues during ligand docking11PDB coordinates have been deposited with the RSCB with accession ID: 1F28. Cell Chemical Biology 2001, 8: 445-457. PMID: 11358692, DOI: 10.1016/s1074-5521(01)00023-0.Peer-Reviewed Original ResearchCitations
Clinical Trials
Current Trials
Brain Changes and Cannabis Use Study
IRB ID2000032181RoleSub InvestigatorPrimary Completion Date05/31/2027Recruiting ParticipantsGenderBothAge18 years - 75 yearsM1 Schizophrenia PET Study
IRB ID2000031171RoleSub InvestigatorPrimary Completion Date04/30/2023Recruiting ParticipantsGenderBothAge18 years - 55 yearsSchizophrenia Spectrum Biomarkers Consortium (SSBC)
IRB ID2000029485RoleSub InvestigatorPrimary Completion Date12/31/2030Recruiting ParticipantsA longitudinal study of the effects of cannabis exposure on neuro-development in adolescents and young adults
IRB ID2000024543RoleSub InvestigatorPrimary Completion Date01/31/2021Recruiting ParticipantsGenderBothAge13 years - 25 yearsSleep Dependent Learning in Schizophrenia and Psychosis Risk Syndrome
IRB ID1201009524RolePrincipal InvestigatorPrimary Completion Date01/31/2022Recruiting ParticipantsGenderBothAge18 years - 55 years
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