2024
The Neural Correlates of Individual Differences in Reinforcement Learning during Pain Avoidance and Reward Seeking
Le T, Oba T, Couch L, McInerney L, Li C. The Neural Correlates of Individual Differences in Reinforcement Learning during Pain Avoidance and Reward Seeking. ENeuro 2024, 11: eneuro.0437-23.2024. PMID: 38365840, PMCID: PMC10901196, DOI: 10.1523/eneuro.0437-23.2024.Peer-Reviewed Original ResearchConceptsSuperior frontal gyrusReward-seekingCingulate cortexNeural correlatesPain avoidanceAction biasDorsal anterior cingulate cortexLeft posterior cingulate cortexAction-outcome associationsGo/No-Go taskAnterior cingulate cortexPosterior cingulate cortexImpact of outcomesHigher learning rateReward trialsFrontal gyrusAvoidance learningMidcingulate cortexNeural substratesAssociative learningAction tendenciesPre-SMAAssociated with activationPrecentral gyrusPostcentral gyrus
2020
Age-Related Changes in the Neural Processes of Reward-Directed Action and Inhibition of Action
Le TM, Chao H, Levy I, Li CR. Age-Related Changes in the Neural Processes of Reward-Directed Action and Inhibition of Action. Frontiers In Psychology 2020, 11: 1121. PMID: 32587547, PMCID: PMC7298110, DOI: 10.3389/fpsyg.2020.01121.Peer-Reviewed Original ResearchInhibition of actionFunctional brain changesRostral anterior cingulate cortexWhole-brain multiple regressionAnterior cingulate cortexMiddle frontal gyrusAge-related changesFunctional magnetic resonanceBrain changesPostcentral gyrusCingulate cortexAnterior insulaFrontal gyrusTrialsProlonged response timeSuccess trialsGo trialsNeural activationReward-directed actionNegative modulationAgeAction inhibitionBrain substratesAge-related slowingReduced activity