Sudheesh A P, PhD
he/him/his
Associate Research Scientist Molecular Cellular and Developmental BiologyDownloadHi-Res Photo
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Associate Research Scientist Molecular Cellular and Developmental Biology
Biography
I am a and ambitious researcher who is trying to apply the knowledge from basic research to understand complex disease-relevant questions. I completed my Ph.D. studying eukaryotic mRNA 3'-end processing and currently trying to understand the role of regulatory RNAs in stem cells and regeneration.
Last Updated on November 16, 2022.
Appointments
Molecular, Cellular, and Developmental Biology
Associate Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- Rajiv Gandhi Centre for Biotechnology, RNA Biology (2019)
- MSc
- Mahatma Gandhi University, Biotechnology (2012)
- BSc
- Bharathiar University, Biotechnology (2010)
Research
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Overview
I am trying to understand the role of small regulatory RNAs in Planarians.
ORCID
0000-0002-1632-147X- View Lab Website
Van Wolfswinkel
Research at a Glance
Yale Co-Authors
Frequent collaborators of Sudheesh A P's published research.
Publications Timeline
A big-picture view of Sudheesh A P's research output by year.
Josien C. van Wolfswinkel, PhD, MSc
7Publications
61Citations
Publications
2026
Host-transposon mutualism supports regeneration in planarians
Lee H, Poulet A, Parambil S, van Wolfswinkel J. Host-transposon mutualism supports regeneration in planarians. Developmental Cell 2026, 61: 1061-1075.e7. PMID: 41916287, PMCID: PMC13047482, DOI: 10.1016/j.devcel.2026.03.001.Peer-Reviewed Original ResearchThis study reveals how the Burro1 transposon supports its planarian host by improving its regenerative abilities, showing that transposons can have mutually beneficial interactions with their host.
2025
Enhanced RNA quality control maintains long-term regenerative ability in planarians
Zelko M, Li D, Parambil S, Poulet A, Verdesca A, Mazeika K, Dasgupta K, van Wolfswinkel J. Enhanced RNA quality control maintains long-term regenerative ability in planarians. Development 2025, 152: dev204762. PMID: 40955864, PMCID: PMC12579931, DOI: 10.1242/dev.204762.Peer-Reviewed Original ResearchCitationsAltmetricOp-Ed: From Research to Reality: The Personal Cost of Academia
Parambil S, Ramu M. Op-Ed: From Research to Reality: The Personal Cost of Academia. Journal Of Life Sciences 2025 DOI: 10.36069/jols/20250503.Commentaries, Editorials and LettersBiology of Hox Genes: Questions and Technological Challenges
Parambil S, De Kumar B. Biology of Hox Genes: Questions and Technological Challenges. Methods In Molecular Biology 2025, 2889: 1-10. PMID: 39745601, DOI: 10.1007/978-1-0716-4322-8_1.ChaptersCitations
2023
piRNA generation is associated with the pioneer round of translation in stem cells
Parambil S, Li D, Zelko M, Poulet A, van Wolfswinkel J. piRNA generation is associated with the pioneer round of translation in stem cells. Nucleic Acids Research 2023, 52: 2590-2608. PMID: 38142432, PMCID: PMC10954484, DOI: 10.1093/nar/gkad1212.Peer-Reviewed Original ResearchCitationsAltmetric
2019
Star-PAP controlled alternative polyadenylation coupled poly(A) tail length regulates protein expression in hypertrophic heart
Sudheesh A, Mohan N, Francis N, Laishram R, Anderson R. Star-PAP controlled alternative polyadenylation coupled poly(A) tail length regulates protein expression in hypertrophic heart. Nucleic Acids Research 2019, 47: 10771-10787. PMID: 31598705, PMCID: PMC6847588, DOI: 10.1093/nar/gkz875.Peer-Reviewed Original ResearchCitationsAltmetric
2018
Nuclear Phosphatidylinositol-Phosphate Type I Kinase α-Coupled Star-PAP Polyadenylation Regulates Cell Invasion
Sudheesh A, Laishram R. Nuclear Phosphatidylinositol-Phosphate Type I Kinase α-Coupled Star-PAP Polyadenylation Regulates Cell Invasion. Molecular And Cellular Biology 2018, 38: e00457-17. PMID: 29203642, PMCID: PMC5809686, DOI: 10.1128/mcb.00457-17.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsBreast NeoplasmsCell Line, TumorCell NucleusFemaleHumansMCF-7 CellsNeoplasm InvasivenessNucleotidyltransferasesPhosphatesPhosphatidylinositol 3-KinasePhosphatidylinositol PhosphatesPhosphorylationPolyadenylationPolynucleotide AdenylyltransferaseProtein BindingRNA PrecursorsRNA Processing, Post-TranscriptionalRNA, Messenger
Academic Achievements & Community Involvement
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Honors
honor The Joan and Tom Steitz Fellowship
03/04/2023Other AwardYale Center for RNA Science and MedicineDetailsUnited States
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Mailing Address
Yale University
Sudheesh A P, Ph.D., Van Wolfswinkel Lab, 266 Whitney Ave, Bass receiving, Yale Science Building
New Haven, Connecticut 06511
United States