2019
Evidence for an association of serum melatonin concentrations with recognition and circadian preferences in patients with schizophrenia
Sahbaz C, Özer O, Kurtulmus A, Kırpınar I, Sahin F, Guloksuz S. Evidence for an association of serum melatonin concentrations with recognition and circadian preferences in patients with schizophrenia. Metabolic Brain Disease 2019, 34: 865-874. PMID: 30758707, DOI: 10.1007/s11011-019-00395-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionCircadian RhythmFemaleHumansMaleMelatoninMiddle AgedPsychiatric Status Rating ScalesRecognition, PsychologySchizophreniaSleepConceptsBody mass indexSerum melatonin concentrationsPittsburgh Sleep Quality IndexHealthy controlsMelatonin concentrationsCognitive impairmentMorningness-Eveningness QuestionnaireHigher body mass indexLower MEQ scoresSleep Quality IndexNegative Syndrome ScaleEnzyme-linked immunosorbentCircadian preferenceMelatonin groupMass indexMelatonergic pathwaysHC groupPatientsNeurodevelopmental originSyndrome ScaleMelatonin levelsPatient samplesSchizophreniaMelatoninMEQ scores
2018
An Economic Evaluation of Coordinated Specialty Care (CSC) Services for First-Episode Psychosis in the U.S. Public Sector.
Murphy SM, Kucukgoncu S, Bao Y, Li F, Tek C, Breitborde NJK, Guloksuz S, Phutane VH, Ozkan B, Pollard JM, Cahill JD, Woods SW, Cole RA, Schoenbaum M, Srihari VH. An Economic Evaluation of Coordinated Specialty Care (CSC) Services for First-Episode Psychosis in the U.S. Public Sector. The Journal Of Mental Health Policy And Economics 2018, 21: 123-130. PMID: 30530872, PMCID: PMC6314808.Peer-Reviewed Original ResearchConceptsSpecialty care servicesPatient costsEarly intervention servicesUsual treatmentSchizophrenia spectrum disordersMonth 12Economic evaluationCare servicesSTEP participantsCommunity mental health centerThird-party payer perspectiveIntervention servicesFirst-episode servicesMonths post randomizationHealthcare service utilizationMental health centersU.S. public sectorTeam-based careCost-offset analysisEligible patientsThird-party payersAntipsychotic exposureED visitsMonth 6Episode psychosis
2015
The impact of electroconvulsive therapy on the tryptophan–kynurenine metabolic pathway
Guloksuz S, Arts B, Walter S, Drukker M, Rodriguez L, Myint A, Schwarz M, Ponds R, van Os J, Kenis G, Rutten B. The impact of electroconvulsive therapy on the tryptophan–kynurenine metabolic pathway. Brain Behavior And Immunity 2015, 48: 48-52. PMID: 25765557, DOI: 10.1016/j.bbi.2015.02.029.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedDepressive DisorderElectroconvulsive TherapyFemaleHumansKynurenic AcidKynurenineMaleMiddle AgedPsychiatric Status Rating ScalesTryptophanYoung AdultConceptsTrp-Kyn pathwayHamilton Depression Rating Scale-17 itemsElectroconvulsive therapyBeck Depression InventoryMechanism of actionKynurenic acidTrp-KynKyn/Trp ratioKYNA/KYN ratioTryptophan-kynurenine metabolic pathwayLast ECT sessionBilateral electroconvulsive therapyKyn/TrpTreatment of depressionMultilevel linear regression analysesKYN metabolitesECT sessionsAntidepressant effectsECT responseBipolar depressionECT treatmentTrp ratioNeuroprotective propertiesKynurenine pathwayNeurotoxic processes
2014
Clinical Features of Night Eating Syndrome among Depressed Patients
Kucukgoncu S, Tek C, Bestepe E, Musket C, Guloksuz S. Clinical Features of Night Eating Syndrome among Depressed Patients. European Eating Disorders Review 2014, 22: 102-108. PMID: 24436087, DOI: 10.1002/erv.2280.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnxiety DisordersBody Mass IndexCircadian RhythmDepressionFeeding and Eating DisordersFeeding BehaviorFemaleHumansInterviews as TopicMaleMiddle AgedObesityPersonality InventoryPrevalencePsychiatric Status Rating ScalesQuality of LifeRegression AnalysisSocioeconomic FactorsStress, PsychologicalSurveys and QuestionnairesSyndromeYoung AdultConceptsPittsburgh Sleep Quality IndexBeck Depression InventoryBeck Anxiety InventoryClinical featuresDepressed patientsDepression InventoryNon-NE patientsNight eating syndromeSleep Quality IndexSample of patientsAnxiety InventorySeverity of anxietyNight Eating QuestionnaireSocio-demographic formSmoking statusDaytime dysfunctionSleep qualityDepressed outpatientsPatientsSyndromeEating QuestionnaireStudy sampleBMISignificant differencesDepression
2013
Minor hemoglobins HbA2 and HbF associate with disease severity in bipolar disorder with a likely protective role of HbA2 against post-partum episodes
İnce B, Guloksuz S, Altınbaş K, Oral E, Alpkan L, Altinoz M. Minor hemoglobins HbA2 and HbF associate with disease severity in bipolar disorder with a likely protective role of HbA2 against post-partum episodes. Journal Of Affective Disorders 2013, 151: 405-408. PMID: 23856286, DOI: 10.1016/j.jad.2013.06.042.Peer-Reviewed Original ResearchMeSH KeywordsAdultBipolar DisorderChromatography, High Pressure LiquidFemaleFetal HemoglobinHemoglobin A2HumansHypoxiaMalePostpartum PeriodPregnancyPsychiatric Status Rating ScalesSeverity of Illness IndexConceptsBipolar disorderEpisode densityProtective roleDisease severityLikely protective roleBrain blood flowElectro-convulsive therapyPositive family historyTotal body weightEuthymic BD patientsHigh-performance liquid chromatographyMyocardial anginaLarge comparative studiesIntermittent hypoxiaHemoglobin levelsCardiac outputDisease characteristicsBD patientsHypoxia hypothesisPostpartum episodesHbF increaseFamily historySevere bipolar disorderBlood flowDrug regimes
2012
Plasma concentrations of soluble cytokine receptors in euthymic bipolar patients with and without subsyndromal symptoms
Cetin T, Guloksuz S, Cetin E, Gazioglu S, Deniz G, Oral E, van Os J. Plasma concentrations of soluble cytokine receptors in euthymic bipolar patients with and without subsyndromal symptoms. BMC Psychiatry 2012, 12: 158. PMID: 23013558, PMCID: PMC3532147, DOI: 10.1186/1471-244x-12-158.Peer-Reviewed Original Research