2023
Gender differences underlying the link between exposome and psychosis
Guloksuz S. Gender differences underlying the link between exposome and psychosis. European Psychiatry 2023, 66: s29-s30. PMCID: PMC10417599, DOI: 10.1192/j.eurpsy.2023.114.Peer-Reviewed Original ResearchGender-related differencesPsychosis riskChildhood adversitySubstance abuse comorbidityAssociation of psychosisObstetric complicationsDifferent symptom dimensionsSeason of birthHigh prevalencePsychotic disordersPubMed databaseSystematic reviewSubstance abusePsychosisSubstance useEnvironmental exposuresWomenUrban upbringingChildhood abuseSymptom dimensionsMenEarly ageRiskExposomeFuture studies
2022
Gender differences in the association between environment and psychosis
Pence AY, Pries LK, Ferrara M, Rutten BPF, van Os J, Guloksuz S. Gender differences in the association between environment and psychosis. Schizophrenia Research 2022, 243: 120-137. PMID: 35287098, DOI: 10.1016/j.schres.2022.02.039.Peer-Reviewed Original ResearchConceptsGender-related differencesChildhood adversityPsychosis riskSubstance useSubstance abuse comorbidityEnvironmental exposuresOnset of illnessAssociation of psychosisObstetric complicationsDifferent symptom dimensionsSeason of birthPsychosis spectrum disordersHigh prevalencePsychotic disordersPubMed databaseSystematic reviewPsychosisWomenChildhood abuseSymptom dimensionsMenEarly ageAssociationPsychosis expressionFurther investigation
2019
Examining the independent and joint effects of molecular genetic liability and environmental exposures in schizophrenia: results from the EUGEI study
Guloksuz S, Pries L, Delespaul P, Kenis G, Luykx J, Lin B, Richards A, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş‐Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran E, Kaymak S, Mihaljevic M, Petrovic S, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz P, García‐Portilla M, Sanjuan J, Aguilar E, Santos J, Jiménez‐López E, Arrojo M, Carracedo A, López G, González‐Peñas J, Parellada M, Maric N, Atbaşog˘lu C, Ucok A, Alptekin K, Saka M, investigators G, Arango C, O'Donovan M, Rutten B, van Os J. Examining the independent and joint effects of molecular genetic liability and environmental exposures in schizophrenia: results from the EUGEI study. World Psychiatry 2019, 18: 173-182. PMID: 31059627, PMCID: PMC6502485, DOI: 10.1002/wps.20629.Peer-Reviewed Original ResearchSchizophrenia spectrum disordersEnvironmental exposuresGene-environment interactionsEtiopathogenesis of schizophreniaAdditive interactionEarly life adversityEarly TwinSeason of birthPolygenic risk scoresSpectrum disorderMultiple common genetic variantsRisk scoreRegular cannabisLifetime historyJoint associationsPRS-SCZCommon genetic variantsHearing impairmentSchizophreniaUnrelated controlsEUGEI studyDisordersFamily studiesGenetic liabilityRisk state