2024
Deficient sleep, altered hypothalamic functional connectivity, depression and anxiety in cigarette smokers
Chen Y, Chaudhary S, Li G, Fucito L, Bi J, Li C. Deficient sleep, altered hypothalamic functional connectivity, depression and anxiety in cigarette smokers. Neuroimage Reports 2024, 4: 100200. PMID: 38605733, PMCID: PMC11008573, DOI: 10.1016/j.ynirp.2024.100200.Peer-Reviewed Original ResearchResting state functional connectivitySeverity of depressionPittsburgh Sleep Quality IndexMotivated behaviorNicotine dependenceFunctional connectivityPittsburgh Sleep Quality Index scoreAchenbach Adult Self-ReportSeverity of alcohol useAssociated with greater severityComorbid nicotine dependenceDeficient sleepAdult Self-ReportHypothalamic functional connectivityHuman Connectome ProjectAnxiety disordersAnxiety severityPublished routinesAnxiety symptomsCircuit dysfunctionGreater severityPsychiatric problemsSleep-wake cyclePoor sleep qualityNeural markers
2022
The effects of androgen deprivation on working memory and quality of life in prostate cancer patients: The roles of hypothalamic connectivity
Chaudhary S, Zhornitsky S, Roy A, Summers C, Ahles T, Li C, Chao HH. The effects of androgen deprivation on working memory and quality of life in prostate cancer patients: The roles of hypothalamic connectivity. Cancer Medicine 2022, 11: 3425-3436. PMID: 35315585, PMCID: PMC9487881, DOI: 10.1002/cam4.4704.Peer-Reviewed Original ResearchConceptsAndrogen deprivation therapyMid-cingulate cortexEffects of ADTFunctional connectivityPrecentral gyrusN-back taskN-back performanceState functional connectivityMontreal Cognitive Assessment scoreHypothalamic functional connectivityProspective observational studyNonmetastatic prostate cancerProstate cancer patientsCognitive Assessment scoreQuality of lifeSustain attentionAffective functionsDeprivation therapyHypothalamic connectivityYears of educationAndrogen deprivationCorrect response rateQOL scoresCancer patientsClinical correlates