2024
Considerations when prescribing opioid agonist therapies for people living with HIV
Tarfa A, Lier A, Shenoi S, Springer S. Considerations when prescribing opioid agonist therapies for people living with HIV. Expert Review Of Clinical Pharmacology 2024, 17: 549-564. PMID: 38946101, PMCID: PMC11299801, DOI: 10.1080/17512433.2024.2375448.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidAnti-HIV AgentsBuprenorphineDelayed-Action PreparationsDelivery of Health CareDrug InteractionsHealth Services AccessibilityHIV InfectionsHumansMethadoneNaltrexoneNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersPre-Exposure ProphylaxisUnited StatesConceptsOpioid agonist therapyOpioid use disorderAntiretroviral therapyAgonist therapyDiagnosed OUDOpioid use disorder managementUse disorderTreatment of opioid use disorderExtended-release naltrexonePotential drug interactionsOpioid use disorder treatmentPrescribed opioid agonist therapyLong-acting formulationPre-exposure prophylaxisOUD outcomesImprove HIV preventionIntersection of HIVOpioid antagonistHIV outcomesHIV epidemicOpioidHIVOpioid use disorder servicesPWHHIV preventionMissed Opportunities for Preexposure Prophylaxis Initiation in Hospitalized Persons With Opioid Use Disorder and Infectious Diseases
Parchinski K, Neirinckx V, Frank C, Di Paola A, Tarfa A, Shenoi S, Vander WyK B, Roth P, Ghantous T, Wegman M, Strong M, Levin F, Brady K, Nunes E, Litwin A, Springer S. Missed Opportunities for Preexposure Prophylaxis Initiation in Hospitalized Persons With Opioid Use Disorder and Infectious Diseases. Open Forum Infectious Diseases 2024, 11: ofae366. PMID: 39022389, PMCID: PMC11252843, DOI: 10.1093/ofid/ofae366.Peer-Reviewed Original ResearchCauses, risks and care circumstances associated with death in older adults diagnosed with HIV in a tertiary centre in Malaysia.
Wong H, Pui Li W, Abdul Kahar M, Chong M, Shenoi S, Rozanova J, Syed Omar S, Neelamegam M, Lee Y, Rajasuriar R. Causes, risks and care circumstances associated with death in older adults diagnosed with HIV in a tertiary centre in Malaysia. International Journal Of STD & AIDS 2024, 35: 710-720. PMID: 38722271, DOI: 10.1177/09564624241250378.Peer-Reviewed Original ResearchOlder adultsART initiationCox proportional multivariate modelsFactors associated with all-cause mortalityOlder ageRisk factorsAIDS-relatedIndependent factors associated with deathAll-cause mortalityFactors associated with deathHIV diagnosisCare circumstancesAssociated with deathChronic comorbiditiesOlder individualsCareIndependent risk factorAnalysed dataAge groupsMultivariate modelAdultsTertiary centreHIVOpportunistic infectionsAge
2023
MENTAL HEALTH VULNERABILITIES AND STRENGTHS OF OLDER WOMEN WITH HIV DURING THE HUMANITARIAN CRISIS IN UKRAINE
Rozanova J, Shenoi S, Zeziulin O, Rich K, Bromberg D, Kiriazova T, Deac A, Earnshaw V. MENTAL HEALTH VULNERABILITIES AND STRENGTHS OF OLDER WOMEN WITH HIV DURING THE HUMANITARIAN CRISIS IN UKRAINE. Innovation In Aging 2023, 7: 137-137. PMCID: PMC10737039, DOI: 10.1093/geroni/igad104.0449.Peer-Reviewed Original ResearchSubstance use disordersHIV diagnosisChronic conditionsDepressive symptomsComorbid substance use disorderAnxiety symptomsSocial supportLikelihood of anxietyMixed effects logistic regression modelsEffects logistic regression modelsLogistic regression modelsMental health vulnerabilitiesPsychological counselingPrimary outcomeLongitudinal cohortHIV disclosureUse disordersSevere anxietySymptomsOlder individualsOlder peopleLogistical regressionMental healthCOVID-19HIVIntegrated Care Models: HIV and Substance Use
Hill K, Kuo I, Shenoi S, Desruisseaux M, Springer S. Integrated Care Models: HIV and Substance Use. Current HIV/AIDS Reports 2023, 20: 286-295. PMID: 37698755, PMCID: PMC11034717, DOI: 10.1007/s11904-023-00667-9.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersSubstance useIntegrated careRecent HIV outbreaksHIV viral suppressionMultidisciplinary care teamHIV virologic suppressionOpioid use disorderRisk of HIVHarm reduction programsSubstance use treatmentEvidence-based strategiesVirologic suppressionViral suppressionHIV outbreakCare teamProvider trainingHIVOnward transmissionHealth outcomesCare servicesClinic leadershipCare integrationMedical literatureCommunity health workers can be trained to identify patients eligible for tuberculosis preventive therapy, but encounter barriers to programme implementation in KwaZulu-Natal, South Africa
Norton S, Moll A, Madi J, Nkomo N, Brooks R, Andrews L, Shenoi S. Community health workers can be trained to identify patients eligible for tuberculosis preventive therapy, but encounter barriers to programme implementation in KwaZulu-Natal, South Africa. African Journal Of AIDS Research 2023, 22: 131-135. PMID: 37337826, DOI: 10.2989/16085906.2023.2213213.Peer-Reviewed Original ResearchConceptsTuberculosis preventive therapyCommunity health workersLargest HIV epidemicCause of deathNon-communicable diseasesHealth workersPreventive therapyRural resource-limited settingsHigh TB incidence ratesFurther implementation researchTB incidence rateRate of referralResource-limited settingsMedian ageTreatment initiationHIV epidemicIncidence rateRural South AfricaHIVInfectious diseasesTuberculosisImplementation researchScreening resultsDiseasePatients
2022
The Initial Response to COVID-19 Disruptions for Older People with HIV in Ukraine
Rozanova J, Rich K, Altice F, Shenoi S, Zaviryukha I, Kiriazova T, Mamedova E, Shipunov O, Yariy V, Deac A, Zeziulin O. The Initial Response to COVID-19 Disruptions for Older People with HIV in Ukraine. Geriatrics 2022, 7: 138. PMID: 36547274, PMCID: PMC9777936, DOI: 10.3390/geriatrics7060138.Peer-Reviewed Original ResearchGeneralised anxiety disorderSymptoms of depressionSymptoms of anxietyHIV treatmentSevere depressionOlder peopleMental healthActive drug useSubstance use disordersFirth logistic regression modelHigher suicidal ideationLogistic regression modelsIndependent correlatesUse disordersTelehealth strategiesDrug useSuicidal ideationSymptomsHIVAnxiety disordersSubstance useDepressionStandardised scalesCOVID-19 restrictionsInitial responseUse of a Mobile Health Intervention by Older Versus Younger People with HIV: Analysis of Usage, Social Support, and Network Interactions
Flickinger T, Campbell B, Timm A, Baee S, Datta D, Shenoi S, Rozanova J, Dillingham R. Use of a Mobile Health Intervention by Older Versus Younger People with HIV: Analysis of Usage, Social Support, and Network Interactions. Telemedicine Reports 2022, 3: 191-200. PMID: 36636167, PMCID: PMC9811827, DOI: 10.1089/tmr.2022.0035.Peer-Reviewed Original ResearchWillingness to Be Vaccinated Against COVID-19 Among People With HIV in the United States: Results From a National Survey
Wickersham JA, Meyer JP, Shenoi S, Altice FL, Barakat LA, Virata M, Olivares M, Maviglia F, Khati A, Shrestha R. Willingness to Be Vaccinated Against COVID-19 Among People With HIV in the United States: Results From a National Survey. Frontiers In Medicine 2022, 9: 886936. PMID: 35847816, PMCID: PMC9280331, DOI: 10.3389/fmed.2022.886936.Peer-Reviewed Original ResearchCOVID-19 infectionCOVID-19 vaccineCOVID-19Undetectable HIV viral loadCOVID-19 vaccination uptakeAnnual influenza vaccinationHIV viral loadVaccine-related concernsNational surveyHIV careInfluenza vaccinationVaccination uptakeViral loadVaccination programSevere diseasePWHVaccineHIVInfectionIntensive outreach effortsTotal populationUnited StatesParticipantsAnnual incomeVast majorityCOVID-19 Vaccine Hesitancy and Associated Factors among People with HIV in the United States: Findings from a National Survey
Shrestha R, Meyer JP, Shenoi S, Khati A, Altice FL, Mistler C, Aoun-Barakat L, Virata M, Olivares M, Wickersham JA. COVID-19 Vaccine Hesitancy and Associated Factors among People with HIV in the United States: Findings from a National Survey. Vaccines 2022, 10: 424. PMID: 35335054, PMCID: PMC8949562, DOI: 10.3390/vaccines10030424.Peer-Reviewed Original ResearchCOVID-19 vaccine hesitancyVaccine hesitancySevere COVID-19 diseaseMean timeSample of PWHCells/mm3COVID-19 historyVaccine-related concernsGreater vaccine hesitancyCOVID-19 vaccineCOVID-19COVID-19 diseaseLower vaccine hesitancyCross-sectional online surveyCD4 countAssociated FactorsSide effectsHIVKey populationsPWHMultivariate linear regressionVaccineCOVID-19 epidemicHesitancyMost participants
2021
Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study
Virata MD, Shenoi SV, Ladines-Lim J, Villanueva MS, Barakat LA. Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study. PLOS ONE 2021, 16: e0260251. PMID: 34851963, PMCID: PMC8635326, DOI: 10.1371/journal.pone.0260251.Peer-Reviewed Original ResearchConceptsOne-year retrospective cohort studyCohort of PWHNon-communicable comorbiditiesPredictors of hospitalizationRetrospective cohort studyChronic lung diseaseLikelihood of hospitalizationSingle-site experienceCOVID-19 infectionNon-communicable diseasesOutcomes of peopleCohort studyHIV diseaseOverall mortalityClinical outcomesLung diseaseCardiovascular diseaseHospitalizationCumulative burdenHIVLater timeframeDiseaseEarly epidemicPWHOutcomesAn expanding HIV epidemic among older adults in Ukraine: Implications for patient-centered care
Rozanova J, Zeziulin O, Rich KM, Altice FL, Kiriazova T, Zaviryukha I, Sosidko T, Gulati K, Carroll C, Shenoi SV. An expanding HIV epidemic among older adults in Ukraine: Implications for patient-centered care. PLOS ONE 2021, 16: e0256627. PMID: 34591848, PMCID: PMC8483339, DOI: 10.1371/journal.pone.0256627.Peer-Reviewed Original ResearchConceptsStandardized mortality ratioMortality rateCause standardized mortality ratioTime of diagnosisGeneral population ratesLate-stage HIVAge-matched groupHigh mortality ratePatient-centered careIncident HIVHIV diagnosisHIV testingHIV incidenceHIV treatmentHIV epidemicMortality ratioTreatment strategiesGeneral populationHIVMortality trendsAge groupsEECA countriesTreatment programSame calendar yearOlder peopleThe Lived Experience of a Newly Diagnosed Older Person With HIV in Ukraine
Allen A, Zaviryukha I, Kiriazova T, Shenoi S, Rozanova J. The Lived Experience of a Newly Diagnosed Older Person With HIV in Ukraine. Qualitative Health Research 2021, 31: 2290-2303. PMID: 34414837, PMCID: PMC8930274, DOI: 10.1177/10497323211026914.Peer-Reviewed Original ResearchConceptsHIV diagnosisCare providersAntiretroviral therapy initiationPrimary care providersHealth care providersFear of stigmaTherapy initiationYounger patientsMiddle-income countriesHIV knowledgeLower riskNew diagnosisHigh mortalityOlder personsOlder peopleDiagnosisLittle dataHIVTraumatic eventsPatientsProvidersMortalityCorrection to: Expansion of a national differentiated service delivery model to support people living with HIV and other chronic conditions in South Africa: a descriptive analysis
Liu L, Christie S, Munsamy M, Roberts P, Pillay M, Shenoi SV, Desai MM, Linnander EL. Correction to: Expansion of a national differentiated service delivery model to support people living with HIV and other chronic conditions in South Africa: a descriptive analysis. BMC Health Services Research 2021, 21: 549. PMID: 34088315, PMCID: PMC8178930, DOI: 10.1186/s12913-021-06561-7.Peer-Reviewed Original ResearchExpansion of a national differentiated service delivery model to support people living with HIV and other chronic conditions in South Africa: a descriptive analysis
Liu L, Christie S, Munsamy M, Roberts P, Pillay M, Shenoi SV, Desai MM, Linnander EL. Expansion of a national differentiated service delivery model to support people living with HIV and other chronic conditions in South Africa: a descriptive analysis. BMC Health Services Research 2021, 21: 463. PMID: 34001123, PMCID: PMC8127180, DOI: 10.1186/s12913-021-06450-z.Peer-Reviewed Original ResearchConceptsNon-communicable diseasesDifferentiated service delivery modelsChronic conditionsChronic diseasesCentral Chronic Medicine DispensingLargest antiretroviral therapy (ART) programmeService delivery modelsManagement of HIVType of medicationAntiretroviral therapy programsHIV service deliveryChronic disease conditionsResource-limited settingsMedicine DispensingMixed-methods evaluationDelivery modelHealth districtHealth facilitiesNoncommunicable diseasesHIVPatientsPatient volumeTherapy programMedicationsDisease“We’ve Got Our Own Beliefs, Attitudes, Myths”: A Mixed Methods Assessment of Rural South African Health Care Workers' Knowledge of and Attitudes Towards PrEP Implementation
Asabor EN, Lett E, Moll A, Shenoi SV. “We’ve Got Our Own Beliefs, Attitudes, Myths”: A Mixed Methods Assessment of Rural South African Health Care Workers' Knowledge of and Attitudes Towards PrEP Implementation. AIDS And Behavior 2021, 25: 2517-2532. PMID: 33763802, PMCID: PMC8450017, DOI: 10.1007/s10461-021-03213-z.Peer-Reviewed Original ResearchConceptsLocal healthcare workersHealthcare workersPrEP implementationHealth care workers' knowledgeHIV pre-exposure prophylaxisSkilled clinical staffPre-exposure prophylaxisImpact of HIVPrEP interventionsHIV prevalenceHCW roleClinical staffTravel burdenMixed-methods assessmentDisproportionate burdenHIVWorkers' knowledgeAdditional concernsSexual behaviorBlack South AfricansBarriers researchersPrEPRisk compensationBurdenImplementation scientists
2020
764. Correlates of Lost to Follow-up Among Newly Diagnosed Older People with HIV in Ukraine
Allen A, Zeziulin O, Postnov O, Rozanova J, Litz T, Zaviryukha I, Kiriazova T, Shenoi S. 764. Correlates of Lost to Follow-up Among Newly Diagnosed Older People with HIV in Ukraine. Open Forum Infectious Diseases 2020, 7: s427-s428. PMCID: PMC7777685, DOI: 10.1093/ofid/ofaa439.954.Peer-Reviewed Original ResearchHIV clinicSecond largest HIV epidemicMethods Retrospective chart reviewOlder peopleRetrospective chart reviewTime of diagnosisAdjusted odds ratioLargest HIV epidemicMultivariate logistic regressionHIV service deliveryResource-limited settingsCorrelates of lossHIV careART prescriptionChart reviewClinical characteristicsYounger patientsHIV outcomesMedian agePoor outcomeHIV epidemicOdds ratioFirst appointmentLTFUHIVMobile Device Usage by Gender Among High-Risk HIV Individuals in a Rural, Resource-Limited Setting
Campbell BR, Choi K, Neils MG, Canan C, Moll A, Dillingham R, Shenoi SV. Mobile Device Usage by Gender Among High-Risk HIV Individuals in a Rural, Resource-Limited Setting. Telemedicine Journal And E-Health 2020, 27: 615-624. PMID: 32835638, PMCID: PMC8215405, DOI: 10.1089/tmj.2020.0218.Peer-Reviewed Original ResearchConceptsMHealth interventionsRural KwaZulu-NatalCare of HIVLack of circumcisionMultivariable logistic regressionMedical male circumcisionResource limited settingsHealthcare messagesCircumcision statusHIV counselingHIV individualsMiddle-income countriesCondomless sexMale circumcisionCondom useCommunity settingsLogistic regressionHIVYoung womenHealthcare interventionsUnderserved populationsKwaZulu-NatalHealth information seekingHealth informationInterventionSocial Support is Key to Retention in Care during Covid-19 Pandemic among Older People with HIV and Substance Use Disorders in Ukraine
Rozanova J, Shenoi S, Zaviryukha I, Zeziulin O, Kiriazova T, Rich K, Mamedova E, Yariy V. Social Support is Key to Retention in Care during Covid-19 Pandemic among Older People with HIV and Substance Use Disorders in Ukraine. Substance Use & Misuse 2020, 55: 1902-1904. PMID: 32666857, PMCID: PMC7523433, DOI: 10.1080/10826084.2020.1791183.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnti-Retroviral AgentsBetacoronavirusComorbidityCoronavirus InfectionsCOVID-19FemaleHealth PersonnelHIV InfectionsHumansMaleMiddle AgedPandemicsPneumonia, ViralRetention in CareSARS-CoV-2Social IsolationSocial SupportSubstance-Related DisordersSurveys and QuestionnairesUkraineConceptsSubstance use disordersUse disordersHuman immunodeficiency virus HIVCOVID-19 pandemicOlder peopleLay health workersSocial supportTreatment interruptionConclusions/Health workersSUD treatmentPharmacological approachesYears old accountTelehealth supportVirus HIVHIVOlder adultsDisordersSuch interventionsPhone surveyTherapyProvision of supportCOVID-19 lockdownPandemicOld account
2019
1883. Factors Associated with Stigma Toward Isoniazid-Preventative Therapy in a Rural Community of South Africa
Palacios C, Kompala T, Moll A, Andrews L, Shenoi S. 1883. Factors Associated with Stigma Toward Isoniazid-Preventative Therapy in a Rural Community of South Africa. Open Forum Infectious Diseases 2019, 6: s51-s52. PMCID: PMC6808667, DOI: 10.1093/ofid/ofz359.113.Peer-Reviewed Original ResearchIsoniazid preventative therapyTB knowledgePresence of stigmaMarital statusPrevention of tuberculosisMultivariable linear regressionRural KwaZulu-Natal ProvinceChi-square testIPT implementationTB screeningTB transmissionHigher knowledge levelMean ageTB scoreHIV stigmaKruskal-Wallis testKnowledge scoreTuberculosisPoor knowledgeLinear regressionHIVMean scoreTotal knowledgeTherapyTreatment