2023
Research objectives and general considerations for pragmatic clinical trials of pain treatments: IMMPACT statement
Hohenschurz-Schmidt D, Cherkin D, Rice A, Dworkin R, Turk D, McDermott M, Bair M, DeBar L, Edwards R, Farrar J, Kerns R, Markman J, Rowbotham M, Sherman K, Wasan A, Cowan P, Desjardins P, Ferguson M, Freeman R, Gewandter J, Gilron I, Grol-Prokopczyk H, Hertz S, Iyengar S, Kamp C, Karp B, Kleykamp B, Loeser J, Mackey S, Malamut R, McNicol E, Patel K, Sandbrink F, Schmader K, Simon L, Steiner D, Veasley C, Vollert J. Research objectives and general considerations for pragmatic clinical trials of pain treatments: IMMPACT statement. Pain 2023, 164: 1457-1472. PMID: 36943273, PMCID: PMC10281023, DOI: 10.1097/j.pain.0000000000002888.Peer-Reviewed Original ResearchConceptsPragmatic trialPain treatmentClinical careSystematic reviewAddiction Clinical Trial TranslationsNetworks (ACTTION) public-private partnershipTraditional efficacy trialsRoutine clinical careDaily clinical carePragmatic clinical trialsEvidence-based treatmentsRelated health policiesInternal validityPain assessmentClinical managementClinical trialsEfficacy trialsConsensus meetingTrial designConsensus discussionTrial objectivesSuch trialsHealth policyTrialsExpert presentations
2015
Deficiencies in reporting of statistical methodology in recent randomized trials of nonpharmacologic pain treatments: ACTTION systematic review
Dworkin JD, McKeown A, Farrar JT, Gilron I, Hunsinger M, Kerns RD, McDermott MP, Rappaport BA, Turk DC, Dworkin RH, Gewandter JS. Deficiencies in reporting of statistical methodology in recent randomized trials of nonpharmacologic pain treatments: ACTTION systematic review. Journal Of Clinical Epidemiology 2015, 72: 56-65. PMID: 26597977, DOI: 10.1016/j.jclinepi.2015.10.019.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsPain treatmentPrimary analysisSystematic reviewNonpharmacologic pain treatmentsRecent randomized trialsJournal of PainQuality of reportingHalf of studiesClinical trial publicationsPercent of studiesNoninterventional trialStatistical methodsPrimary outcomeRandomized trialsClinical trialsTrial publicationsPainTrial resultsTrialsStatistical methodologyTreatmentReviewDeficiencyReportingA Systematic Review of Technology-assisted Self-Management Interventions for Chronic Pain
Heapy AA, Higgins DM, Cervone D, Wandner L, Fenton BT, Kerns RD. A Systematic Review of Technology-assisted Self-Management Interventions for Chronic Pain. The Clinical Journal Of Pain 2015, 31: 470-492. PMID: 25411862, DOI: 10.1097/ajp.0000000000000185.Peer-Reviewed Original ResearchConceptsSelf-management interventionsSystematic reviewChronic painTechnology-assisted interventionsChronic pain self-management interventionPain self-management interventionEffect of treatmentHeterogeneity of methodsNoncancer painCochrane DatabaseFuture trialsTreatment modalitiesOvid MEDLINEPerson treatmentElectronic searchPainOvid PsychInfoSuperior modalityComparison groupInteractive voice responsePsychological interventionsInterventionIndividual studiesModalitiesTreatment
2013
Instruments to assess patient‐reported safety, efficacy, or misuse of current opioid therapy for chronic pain: A systematic review
Becker WC, Fraenkel L, Edelman J, Holt SR, Glover J, Kerns RD, Fiellin DA. Instruments to assess patient‐reported safety, efficacy, or misuse of current opioid therapy for chronic pain: A systematic review. Pain 2013, 154: 905-916. PMID: 23601625, PMCID: PMC3683236, DOI: 10.1016/j.pain.2013.02.031.Peer-Reviewed Original ResearchConceptsPatient-reported safetyOpioid therapyChronic painInclusion criteriaSystematic reviewOngoing opioid therapyPsychometric testsLack of testingEligible studiesClinical practiceInitial searchStatistical significanceDiagnostic accuracy testingPainEfficacyTherapyEfficacy itemsContent expertsSafetyLimited assessmentReviewLiterature reviewGeneralizability limitationsFurther researchIndividual items