2022
The Use of Extracorporeal Membrane Oxygenation as a Bridge to Bone Marrow Transplantation in a Patient With High-risk Acute Myeloid Leukemia
Nader M, Bonde P, Massaro S, Giuliano J, Shah N. The Use of Extracorporeal Membrane Oxygenation as a Bridge to Bone Marrow Transplantation in a Patient With High-risk Acute Myeloid Leukemia. Journal Of Pediatric Hematology/Oncology 2022, 45: 18-20. PMID: 36219701, DOI: 10.1097/mph.0000000000002567.Peer-Reviewed Original ResearchConceptsHigh-risk acute myeloid leukemiaExtracorporeal membrane oxygenationAcute myeloid leukemiaMyeloid leukemiaMembrane oxygenationAllogeneic hematopoietic stem cell transplantationHematopoietic stem cell transplantationVenoarterial extracorporeal membrane oxygenationTransplantation 2 monthsStem cell transplantationBone marrow transplantationMultiorgan dysfunction syndromeExtracorporeal life supportMarrow transplantationCell transplantationPatient selectionSeptic shockDysfunction syndromeRisk stratificationCardiogenic shockBiventricular failureTreatment protocolsCirculatory supportYounger ageMultidisciplinary approach
2020
Impact of Preoperative Lymphopenia on Survival Following Left Ventricular Assist Device Placement
Stawiarski K, Agboola O, Park J, Geirsson A, Jacoby D, Bellumkonda L, Ahmad T, Chou J, Lee F, Mangi A, Bonde P. Impact of Preoperative Lymphopenia on Survival Following Left Ventricular Assist Device Placement. ASAIO Journal 2020, 67: 650-657. PMID: 33074860, DOI: 10.1097/mat.0000000000001289.Peer-Reviewed Original ResearchConceptsAbsolute lymphocyte countCause mortalityLymphopenia groupLeft ventricular assist device patientsVentricular assist device patientsVentricular assist device placementCox proportional hazards modelImpact of lymphopeniaHeart failure populationKaplan-Meier plotsFurther clinical investigationProportional hazards modelLog-rank statisticsDurable LVADPreoperative lymphopeniaLVAD placementLymphocyte countLymphopenic patientsDevice patientsSingle centerPoor outcomePrognostic implicationsALC levelsFailure populationStudy population
2011
Successful Lung Retransplantation After Extended Use of Extracorporeal Membrane Oxygenation as a Bridge
Shigemura N, Bermudez C, Bhama J, Bonde P, Thacker J, Toyoda Y. Successful Lung Retransplantation After Extended Use of Extracorporeal Membrane Oxygenation as a Bridge. Transplantation Proceedings 2011, 43: 2063-2065. PMID: 21693326, DOI: 10.1016/j.transproceed.2011.02.008.Peer-Reviewed Original ResearchConceptsEarly allograft dysfunctionExtracorporeal membrane oxygenationLung transplantationAllograft dysfunctionMembrane oxygenationRedo lung transplantationAcute cellular rejectionDouble lung transplantationSingle lung transplantationMajor clinical challengeCellular rejectionLung retransplantationClinical challengeSuccessful outcomeTransplantationPatientsDysfunctionOxygenationSuccessful useExtended useRetransplantation
2004
Electroporative transfection with KGF-1 DNA improves wound healing in a diabetic mouse model
Marti G, Ferguson M, Wang J, Byrnes C, Dieb R, Qaiser R, Bonde P, Duncan M, Harmon J. Electroporative transfection with KGF-1 DNA improves wound healing in a diabetic mouse model. Gene Therapy 2004, 11: 1780-1785. PMID: 15470477, DOI: 10.1038/sj.gt.3302383.Peer-Reviewed Original ResearchConceptsKeratinocyte growth factorDiabetic mouse modelMouse modelWound healing modelExcisional woundsWound closureEpithelial cell proliferationRT-PCR assaysDiabetic miceDiabetic individualsUnresolved inflammationDNA injectionMouse wound-healing modelUntreated groupSingle injectionDay 12KGF mRNAELISA assaysKGF proteinHistological analysisGrowth factorSubsequent electroporationNaked DNA injectionCell proliferationWounds
2002
Endoscopic vein harvest: early results of a prospective trial with open vein harvest.
Bonde P, Graham A, MacGowan S. Endoscopic vein harvest: early results of a prospective trial with open vein harvest. The Heart Surgery Forum 2002, 5 Suppl 4: s378-91. PMID: 12759210.Peer-Reviewed Original ResearchConceptsEndoscopic vein harvestSaphenous vein harvestVein harvestOperative timeEVH groupPostoperative painWound painVein qualityFisher s exact testLeg wound infectionsOpen vein harvestPost-operative painOverall operative timeGreater patient satisfactionWound healingExtended treatment periodMann-Whitney UEarly ambulationProspective trialASEPSIS scoreSerious morbidityOVH groupWound infectionPatient satisfactionTreatment period