2024
Genetic and non-genetic predictors of risk for opioid dependence.
Na P, Deak J, Kranzler H, Pietrzak R, Gelernter J. Genetic and non-genetic predictors of risk for opioid dependence. Psychological Medicine 2024, 54: 1779-1786. PMID: 38317430, PMCID: PMC11132928, DOI: 10.1017/s0033291723003732.Peer-Reviewed Original ResearchPolygenic risk scoresMulti-trait analysis of genome-wide association studyOpioid use disorderPosttraumatic stress disorderPsychosocial/environmental factorsAnalysis of genome-wide association studiesHigher education levelGenome-wide association studiesNon-genetic predictorsEuropean-ancestry adultsEtiology of ODPublic health crisisPsychosocial factorsPolygenic riskMulti-trait analysisEducation levelPsychosocial environmentHousehold incomeRisk scoreAssociation studiesOpioid dependenceDiagnosis of ODLifetime diagnosisYale-PennAssociated with OD
2023
The Current Status of Medical Student Education on Opioids
Jegede O, Na P, Petrakis I, Muvvala S. The Current Status of Medical Student Education on Opioids. 2023, 121-138. DOI: 10.1093/oxfordhb/9780197618431.013.5.Peer-Reviewed Original Research
2022
National trends of suicidal ideation and mental health services use among US adults with opioid use disorder, 2009–2020
Na PJ, Bommersbach TJ, Petrakis IL, Rhee TG. National trends of suicidal ideation and mental health services use among US adults with opioid use disorder, 2009–2020. EClinicalMedicine 2022, 54: 101696. PMID: 36267498, PMCID: PMC9576812, DOI: 10.1016/j.eclinm.2022.101696.Peer-Reviewed Original ResearchMental health service useOpioid use disorderHealth service usePast-year opioid use disorderMental health servicesPrevalence of SISuicidal ideationService useUse disordersHealth servicesUS adultsPast-year major depressive episodeInpatient mental health servicesMental health service utilizationHealth service utilizationMajor depressive episodePast-year suicidal ideationCo-occurring depressionSedative use disorderClinical characteristicsPrescription medicationsDepressive episodeOdds ratioService utilizationRoutine screeningCo-occurring Depression and Suicidal Ideation in Opioid Use Disorder: Prevalence and Response During Treatment With Buprenorphine-Naloxone and Injection Naltrexone.
Na PJ, Scodes J, Fishman M, Rotrosen J, Nunes EV. Co-occurring Depression and Suicidal Ideation in Opioid Use Disorder: Prevalence and Response During Treatment With Buprenorphine-Naloxone and Injection Naltrexone. The Journal Of Clinical Psychiatry 2022, 83 PMID: 35452194, DOI: 10.4088/jcp.21m14140.Peer-Reviewed Original ResearchConceptsOpioid use disorderWeeks of treatmentBuprenorphine-naloxoneCo-occurring depressionSevere depressionWeek 4Mild depressionUse disordersSuicidal ideationMedication treatment groupExtended-release naltrexoneInitiation of treatmentOpioid use outcomesPrevalence of depressionRisk of relapseDeaths of despairInjection naltrexoneXR-NTXOpioid useDepression treatmentFrequent historyTreatment groupsPatientsLogistic regressionAnxiety disorders