2008
Issues in the Design of a Pilot Concept-Based Query Interface for the Neuroinformatics Information Framework
Marenco L, Li Y, Martone ME, Sternberg PW, Shepherd GM, Miller PL. Issues in the Design of a Pilot Concept-Based Query Interface for the Neuroinformatics Information Framework. Neuroinformatics 2008, 6: 229-239. PMID: 18953674, PMCID: PMC2664632, DOI: 10.1007/s12021-008-9035-9.Peer-Reviewed Original ResearchConceptsNeuroscience Information FrameworkQuery interfaceBiomedical information retrievalInformation frameworkInformation retrievalResource registryDocument archivesBiomedical vocabulariesSingle interfaceStandardized vocabularyCurrent versionDetailed exampleInterfaceResourcesFrameworkOntologyPilot conceptVocabularyRetrievalIssuesCertain lessonsBackground issuesSearchArchivesPrimary resources
2007
The DART classification of unannotated transcription within the ENCODE regions: Associating transcription with known and novel loci
Rozowsky JS, Newburger D, Sayward F, Wu J, Jordan G, Korbel JO, Nagalakshmi U, Yang J, Zheng D, Guigó R, Gingeras TR, Weissman S, Miller P, Snyder M, Gerstein MB. The DART classification of unannotated transcription within the ENCODE regions: Associating transcription with known and novel loci. Genome Research 2007, 17: 732-745. PMID: 17567993, PMCID: PMC1891334, DOI: 10.1101/gr.5696007.Peer-Reviewed Original ResearchEvidence for association between multiple complement pathway genes and AMD
Dinu V, Miller PL, Zhao H. Evidence for association between multiple complement pathway genes and AMD. Genetic Epidemiology 2007, 31: 224-237. PMID: 17266113, DOI: 10.1002/gepi.20204.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsPathway levelGenome-wide association studiesGenome-wide levelWide association studyGenome levelAdditional genesPathway genesAssociation studiesBiological knowledgeSNP signalsComplement factor HGenotype dataGenesNucleotide polymorphismsForms of AMDComplement pathway genesRisk allelesFactor HMBL2 single-nucleotide polymorphismsIntronsHaplotypesComplement pathwayAllelesPathway
2006
Dynamic Tables: An Architecture for Managing Evolving, Heterogeneous Biomedical Data in Relational Database Management Systems
Corwin J, Silberschatz A, Miller PL, Marenco L. Dynamic Tables: An Architecture for Managing Evolving, Heterogeneous Biomedical Data in Relational Database Management Systems. Journal Of The American Medical Informatics Association 2006, 14: 86-93. PMID: 17068350, PMCID: PMC2215074, DOI: 10.1197/jamia.m2189.Peer-Reviewed Original ResearchConceptsBiomedical dataRelational database management systemRelational database technologySemantic data modelDatabase management systemRelational database enginePerformance of queriesHeterogeneous biomedical dataBiomedical informatics researchersDatabase engineDatabase technologyDatabase schemaData sparsityBioinformatics communityData modelInformatics researchersEvolution issuesTypes of dataManagement systemPerformance resultsRelational designClinical informaticsArchitecturePast approachesRelational techniques
2001
Maintaining and Incrementally Revalidating a Computer-Based Clinical Guideline: A Case Study
Miller P, Frawley S, Sayward F. Maintaining and Incrementally Revalidating a Computer-Based Clinical Guideline: A Case Study. Journal Of Biomedical Informatics 2001, 34: 99-111. PMID: 11515416, DOI: 10.1006/jbin.2001.1011.Peer-Reviewed Original ResearchDomain-constrained Generation of Clinical Condition Sets to Help Test Computer-based Clinical Guidelines
Miller P. Domain-constrained Generation of Clinical Condition Sets to Help Test Computer-based Clinical Guidelines. Journal Of The American Medical Informatics Association 2001, 8: 131-145. PMID: 11230382, PMCID: PMC134553, DOI: 10.1136/jamia.2001.0080131.Peer-Reviewed Original ResearchExploring the Utility of Demographic Data and Vaccination History Data in the Deduplication of Immunization Registry Patient Records
Miller P, Frawley S, Sayward F. Exploring the Utility of Demographic Data and Vaccination History Data in the Deduplication of Immunization Registry Patient Records. Journal Of Biomedical Informatics 2001, 34: 37-50. PMID: 11376541, DOI: 10.1006/jbin.2001.1001.Peer-Reviewed Original ResearchIntegration of Multidisciplinary Sensory Data
Miller P, Nadkarni P, Singer M, Marenco L, Hines M, Shepherd G. Integration of Multidisciplinary Sensory Data. Journal Of The American Medical Informatics Association 2001, 8: 34-48. PMID: 11141511, PMCID: PMC134590, DOI: 10.1136/jamia.2001.0080034.Peer-Reviewed Original ResearchConceptsNeuroinformatics researchFlexible data modelDiverse heterogeneous dataHuman Brain ProjectNew informatics technologiesHeterogeneous dataData modelSensory dataRelated toolsInformatics technologiesBrain ProjectBuilding databaseSingle unifying frameworkUnifying frameworkProject approachIntegrationComputer model
2000
IMM/Scrub: A Domain-Specific Tool for the Deduplication of Vaccination History Records in Childhood Immunization Registries
Miller P, Frawley S, Sayward F. IMM/Scrub: A Domain-Specific Tool for the Deduplication of Vaccination History Records in Childhood Immunization Registries. Journal Of Biomedical Informatics 2000, 33: 126-143. PMID: 10854120, DOI: 10.1006/cbmr.1999.1534.Peer-Reviewed Original ResearchConceptsImmunization registryAcademic medical centerDomain-specific toolsData cleaning processImmunization databaseVaccine seriesCombination vaccinesMedical CenterHistory recordsPreliminary experienceIMM/Dose numberDosesDoseRegistryDeduplicationPilot implementationDifferent preparationsPilot toolAdditional assistanceVaccineForecasting programImplementationNumber of factorsInformatics issues in the national dissemination of a computer-based clinical guideline: a case study in childhood immunization.
Miller P, Frawley S, Sayward F. Informatics issues in the national dissemination of a computer-based clinical guideline: a case study in childhood immunization. AMIA Annual Symposium Proceedings 2000, 580-4. PMID: 11079950, PMCID: PMC2243834.Peer-Reviewed Original ResearchExploring the Degree of Concordance of Coded and Textual Data in Answering Clinical Queries from a Clinical Data Repository
Stein H, Nadkarni P, Erdos J, Miller P. Exploring the Degree of Concordance of Coded and Textual Data in Answering Clinical Queries from a Clinical Data Repository. Journal Of The American Medical Informatics Association 2000, 7: 42-54. PMID: 10641962, PMCID: PMC61454, DOI: 10.1136/jamia.2000.0070042.Peer-Reviewed Original Research
1999
Organization of Heterogeneous Scientific Data Using the EAV/CR Representation
Nadkarni P, Marenco L, Chen R, Skoufos E, Shepherd G, Miller P. Organization of Heterogeneous Scientific Data Using the EAV/CR Representation. Journal Of The American Medical Informatics Association 1999, 6: 478-493. PMID: 10579606, PMCID: PMC61391, DOI: 10.1136/jamia.1999.0060478.Peer-Reviewed Original ResearchConceptsEAV/CRHeterogeneous scientific dataPhysical database schemaStorage of dataInterobject relationshipsDatabase schemaHeterogeneous dataMedical domainComplex objectsScientific domainsClinical patient recordsSchemaBiomedical databasesRepresentationScientific dataPatient recordsSuch purposesDatabaseValue representationDomainObjectsParadigmDataUsing semantic constraints to help verify the completeness of a computer-based clinical guideline for childhood immunization
Miller D, Frawley S, Miller P. Using semantic constraints to help verify the completeness of a computer-based clinical guideline for childhood immunization. Computer Methods And Programs In Biomedicine 1999, 58: 267-280. PMID: 10094231, DOI: 10.1016/s0169-2607(98)00090-x.Peer-Reviewed Original ResearchExploring three approaches for handling incomplete patient histories in a computer-based guideline for childhood immunization.
Miller P, Frawley S, Sayward F. Exploring three approaches for handling incomplete patient histories in a computer-based guideline for childhood immunization. AMIA Annual Symposium Proceedings 1999, 878-82. PMID: 10566486, PMCID: PMC2232702.Peer-Reviewed Original ResearchNeuronal database integration: the Senselab EAV data model.
Marenco L, Nadkarni P, Skoufos E, Shepherd G, Miller P. Neuronal database integration: the Senselab EAV data model. AMIA Annual Symposium Proceedings 1999, 102-6. PMID: 10566329, PMCID: PMC2232788.Peer-Reviewed Original Research
1998
The Human Brain Project: neuroinformatics tools for integrating, searching and modeling multidisciplinary neuroscience data
Shepherd G, Mirsky J, Healy M, Singer M, Skoufos E, Hines M, Nadkarni P, Miller P. The Human Brain Project: neuroinformatics tools for integrating, searching and modeling multidisciplinary neuroscience data. Trends In Neurosciences 1998, 21: 460-468. PMID: 9829685, DOI: 10.1016/s0166-2236(98)01300-9.Peer-Reviewed Original ResearchTools for Immunization Guideline Knowledge Maintenance I. Automated Generation of the Logic “Kernel” for Immunization Forecasting
Miller P. Tools for Immunization Guideline Knowledge Maintenance I. Automated Generation of the Logic “Kernel” for Immunization Forecasting. Journal Of Biomedical Informatics 1998, 31: 172-189. PMID: 9628749, DOI: 10.1006/cbmr.1998.1472.Peer-Reviewed Original ResearchTools for Immunization Guideline Knowledge Maintenance II. Automated Web-Based Generation of User-Customized Test Cases
Miller P, Frawley S, Brandt C, Sayward F. Tools for Immunization Guideline Knowledge Maintenance II. Automated Web-Based Generation of User-Customized Test Cases. Journal Of Biomedical Informatics 1998, 31: 190-208. PMID: 9628750, DOI: 10.1006/cbmr.1998.1471.Peer-Reviewed Original ResearchManaging Attribute–Value Clinical Trials Data Using the ACT/DB Client–Server Database System
Nadkarni P, Brandt C, Frawley S, Sayward F, Einbinder R, Zelterman D, Schacter L, Miller P. Managing Attribute–Value Clinical Trials Data Using the ACT/DB Client–Server Database System. Journal Of The American Medical Informatics Association 1998, 5: 139-151. PMID: 9524347, PMCID: PMC61285, DOI: 10.1136/jamia.1998.0050139.Peer-Reviewed Original ResearchConceptsClient-server database systemsReuse of parametersData entryOracle serverDatabase applicationsDatabase systemsObject dataUNIX platformsDictionary searchData typesInitial deploymentLogical groupingPurposes of displaySuch dataStandard reportPilot useServerIndexingAnalysis programMachineDeploymentPlatformReuseClientsIssues in accommodating national changes and local variation in a computer-based guideline for childhood immunization and in related knowledge maintenance tools.
Miller P, Frawley S, Sayward F. Issues in accommodating national changes and local variation in a computer-based guideline for childhood immunization and in related knowledge maintenance tools. AMIA Annual Symposium Proceedings 1998, 563-7. PMID: 9929282, PMCID: PMC2232304.Peer-Reviewed Original ResearchConceptsChildhood immunizationNational recommendationsNew national recommendationsClinical practice guidelinesIndian Health ServiceVaccine seriesComputer-based guidelinePractice guidelinesPractice variationImmunization registryHealth servicesImmunizationUS Indian Health ServiceIMM/ServeGuidelinesNational changesRegistry