2021
A critical role for MSR1 in vesicular stomatitis virus infection of the central nervous system
Yang D, Lin T, Li C, Harrison A, Geng T, Wang P. A critical role for MSR1 in vesicular stomatitis virus infection of the central nervous system. IScience 2021, 24: 102678. PMID: 34169243, PMCID: PMC8208900, DOI: 10.1016/j.isci.2021.102678.Peer-Reviewed Original ResearchMacrophage scavenger receptor 1Vesicular stomatitis virus infectionCentral nervous systemStomatitis virus infectionSpinal cordVirus infectionNervous systemLethal VSV infectionMsr1 deficient miceM2 macrophage polarizationWild-type miceInnate immune responseReceptor-dependent mannerScavenger receptor 1Cellular entryViral loadReduced morbidityImmune responseMacrophage polarizationVSV infectionMSR1 expressionViral pathogenesisReceptor 1Bacterial infectionsHost defense
2020
Mechanisms of SARS-CoV-2 Transmission and Pathogenesis
Harrison AG, Lin T, Wang P. Mechanisms of SARS-CoV-2 Transmission and Pathogenesis. Trends In Immunology 2020, 41: 1100-1115. PMID: 33132005, PMCID: PMC7556779, DOI: 10.1016/j.it.2020.10.004.Peer-Reviewed Original ResearchConceptsSARS-CoV-2Severe acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Coronavirus infectious disease 2019Respiratory syndrome coronavirus 2SARS-CoV-2 transmissionTissue tropismSyndrome coronavirus 2SARS-CoV-2 researchBroad tissue tropismCoronavirus 2Pathogenic coronavirusesDisease 2019Immune antagonismTherapeutic testingAnimal modelsViral pathogenesisVaccine developmentPathogenesisTropismFuture investigationsHuman population