1984
Method for determining whether a gene of Escherichia coli is essential: application to the polA gene
Joyce C, Grindley N. Method for determining whether a gene of Escherichia coli is essential: application to the polA gene. Journal Of Bacteriology 1984, 158: 636-643. PMID: 6233260, PMCID: PMC215477, DOI: 10.1128/jb.158.2.636-643.1984.Peer-Reviewed Original ResearchConceptsPolA geneTarget genesRich mediumEscherichia coliPhage lambda vectorTarget lociBacterial chromosomeHomologous recombinationPhysical mapProphage excisionDNA segmentsMinimal mediumAntibiotic resistance genesPolymerase 3Recombinational eventsLambda vectorGenesResistance genesChromosomal deletionsDeletionFunctional fragmentsExonucleaseMarked deletionPhagesPresence of plasmids
1981
Analysis of the structure and function of the kanamycin-resistance transposon Tn903.
Grindley N, Joyce C. Analysis of the structure and function of the kanamycin-resistance transposon Tn903. Cold Spring Harbor Symposia On Quantitative Biology 1981, 45 Pt 1: 125-33. PMID: 6271455, DOI: 10.1101/sqb.1981.045.01.021.Peer-Reviewed Original Research
1980
Genetic and DNA sequence analysis of the kanamycin resistance transposon Tn903.
Grindley N, Joyce C. Genetic and DNA sequence analysis of the kanamycin resistance transposon Tn903. Proceedings Of The National Academy Of Sciences Of The United States Of America 1980, 77: 7176-7180. PMID: 6261245, PMCID: PMC350464, DOI: 10.1073/pnas.77.12.7176.Peer-Reviewed Original Research