1990
The two functional domains of gamma delta resolvase act on the same recombination site: implications for the mechanism of strand exchange.
Dröge P, Hatfull G, Grindley N, Cozzarelli N. The two functional domains of gamma delta resolvase act on the same recombination site: implications for the mechanism of strand exchange. Proceedings Of The National Academy Of Sciences Of The United States Of America 1990, 87: 5336-5340. PMID: 2164677, PMCID: PMC54318, DOI: 10.1073/pnas.87.14.5336.Peer-Reviewed Original ResearchConceptsDNA-protein complexesRecombination sitesSite-specific recombinationGamma delta resolvaseDNA exchangeCatalytic domainStrand exchangeFunctional domainsResolvaseResolvase subunitsDNA strandsRes sitesSynaptic complexDNAStrand breakageRecombinationReunion eventDomainSitesComplexesSubunitsStrandsBreakageSynaptosomes
1981
Transposon-mediated site-specific recombination in vitro: DNA cleavage and protein-DNA linkage at the recombination site
Reed R, Grindley N. Transposon-mediated site-specific recombination in vitro: DNA cleavage and protein-DNA linkage at the recombination site. Cell 1981, 25: 721-728. PMID: 6269756, DOI: 10.1016/0092-8674(81)90179-3.Peer-Reviewed Original ResearchConceptsSite-specific recombinationTransposable element gamma deltaDNA cleavageTnpR genePalindromic sequence 5'Intercistronic regionSequence 5DNA moleculesResolution siteResolvaseSame substrate moleculeRecombination sitesAbsence of Mg2Substrate moleculesGenesSame repliconRecombinationDNACleavageTransposonRes sitesSites