2022
Reduced Cross-Frequency Coupling and Daytime Sleepiness in Obstructive Sleep Apnea Patients
Gouveris H, Koirala N, Anwar A, Ding H, Ludwig K, Huppertz T, Matthias C, Groppa S, Muthuraman M. Reduced Cross-Frequency Coupling and Daytime Sleepiness in Obstructive Sleep Apnea Patients. Biology 2022, 11: 700. PMID: 35625429, PMCID: PMC9138271, DOI: 10.3390/biology11050700.Peer-Reviewed Original ResearchRespiratory disturbance indexObstructive sleep apneaCortical sensorimotor areasOSA patientsSensorimotor areasRespiratory distressCross-frequency couplingObstructive sleep apnea patientsEpworth Sleepiness ScaleSleep apnea patientsSleep stagesDistinct sleep stagesMotor dysfunctionSleep apneaPatient groupApnea patientsDaytime sleepinessSleepiness ScalePatientsPolysomnography recordingsObjective markersSubjective sleepinessDisturbance indexSleepinessDistress
2020
Cross-frequency coupling between gamma oscillations and deep brain stimulation frequency in Parkinson’s disease
Muthuraman M, Bange M, Koirala N, Ciolac D, Pintea B, Glaser M, Tinkhauser G, Brown P, Deuschl G, Groppa S. Cross-frequency coupling between gamma oscillations and deep brain stimulation frequency in Parkinson’s disease. Brain 2020, 143: 3393-3407. PMID: 33150359, PMCID: PMC7116448, DOI: 10.1093/brain/awaa297.Peer-Reviewed Original ResearchConceptsDeep brain stimulationBrain stimulationParkinson's diseaseStimulation frequencyCross-frequency couplingMotor symptomsSubthalamic nucleusGamma oscillationsDeep Brain Stimulation FrequencyOscillatory activityPhysiological neural activityMotor function recoveryEffective deep brain stimulationHigh-frequency stimulationPathological oscillatory activityCross-frequency interactionsCortico-subcortical networksDifferent oscillatory activitiesSymptom controlParietal cortex regionsClinical effectsFunction recoverySymptom alleviationMotor impairmentSubcortical regions