2018
Diffuse cardiac fibrosis quantification in early systemic sclerosis by magnetic resonance imaging and correlation with skin fibrosis
Lee DC, Hinchcliff ME, Sarnari R, Stark MM, Lee J, Koloms K, Hoffmann A, Carns M, Thakrar A, Aren K, Varga J, Aquino A, Carr JC, Benefield BC, Shah SJ. Diffuse cardiac fibrosis quantification in early systemic sclerosis by magnetic resonance imaging and correlation with skin fibrosis. Journal Of Scleroderma And Related Disorders 2018, 3: 159-169. PMID: 29808171, PMCID: PMC5969530, DOI: 10.1177/2397198318762888.Peer-Reviewed Original ResearchEarly systemic sclerosisT1 mapping parametersSystemic sclerosisSSc patientsDiffuse myocardial fibrosisT1 mapping indicesSkin scoreMyocardial fibrosisSkin fibrosisCardiac structure/functionRodnan skin scoreCardiac magnetic resonance T1 mappingT1 mappingMagnetic resonance imagingMagnetic resonance T1 mappingCardiac involvementCardiovascular evaluationConsecutive patientsClinical studiesPatientsResonance imagingFibrosisFibrosis quantificationCine imagingSclerosis
2012
Prevalence, prognosis, and factors associated with left ventricular diastolic dysfunction in systemic sclerosis.
Hinchcliff M, Desai CS, Varga J, Shah SJ. Prevalence, prognosis, and factors associated with left ventricular diastolic dysfunction in systemic sclerosis. Clinical And Experimental Rheumatology 2012, 30: s30-7. PMID: 22338601, PMCID: PMC3507505.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedChicagoChi-Square DistributionComorbidityDiastoleEchocardiography, DopplerFemaleHumansLinear ModelsMaleMiddle AgedMultivariate AnalysisPrevalencePrognosisProportional Hazards ModelsProspective StudiesRegistriesRetrospective StudiesRisk AssessmentRisk FactorsScleroderma, SystemicSystoleTime FactorsVentricular Dysfunction, LeftVentricular Function, LeftConceptsLV diastolic dysfunctionLeft ventricular diastolic dysfunctionVentricular diastolic dysfunctionDiastolic dysfunctionRisk of deathSystemic sclerosisDisease durationEarly mitral annular velocityMultivariable Cox regression analysisSSc disease durationTissue Doppler eLV systolic dysfunctionPulmonary function testsMitral annular velocityCoronary artery diseaseCox regression analysisMultivariable linear regressionSystemic hypertensionSystolic dysfunctionClinical characteristicsDoppler EImpaired relaxationArtery diseaseClinical factorsConsecutive patients