2015
Immune regulatory and neuroprotective properties of preimplantation factor: From newborn to adult
Barnea E, Almogi-Hazan O, Or R, Mueller M, Ria F, Weiss L, Paidas M. Immune regulatory and neuroprotective properties of preimplantation factor: From newborn to adult. Pharmacology & Therapeutics 2015, 156: 10-25. PMID: 26546485, DOI: 10.1016/j.pharmthera.2015.10.008.Peer-Reviewed Original ResearchConceptsPreImplantation FactorNeurological disordersAdverse maternal environmentSynthetic preimplantation factorEarly adverse eventsHigh safety profileFast track designationComplex neurological disorderEmbryonic-maternal interactionColon ulcerationPIF's effectHost diseaseLeukemia effectAdverse eventsLiver inflammationTransplant acceptanceBrain infectionNeuroprotective effectsAutoimmune disordersImmune suppressionNeuroprotective propertiesImmune modulationNeonatal prematuritySupraphysiological dosesSkin ulceration
2013
Immune Regulation and Oxidative Stress Reduction by Preimplantation Factor following Syngeneic or Allogeneic Bone Marrow Transplantation
Shainer R, Azar Y, Almogi-Hazan O, Bringer R, Compton S, Paidas M, Barnea E, Or R. Immune Regulation and Oxidative Stress Reduction by Preimplantation Factor following Syngeneic or Allogeneic Bone Marrow Transplantation. Conference Papers In Science 2013, 2013: 1-8. DOI: 10.1155/2013/718031.Peer-Reviewed Original ResearchBone marrow transplantationMarrow transplantationImmune responseAllogeneic bone marrow transplantationSyngeneic bone marrow transplantationAllogenic bone marrow transplantationImmune regulatory effectsProinflammatory gene expressionINOS gene expressionOxidative stress reductionImmune restorationPreImplantation FactorHost diseaseColon inflammationTransplant acceptanceINOS expressionSystemic immunityImmune regulationGene expressionMurine modelHematological diseasesWeight recoveryTransplantationOxidative stressTransplant success