2000
Regulation of DRA and AE1 in rat colon by dietary Na depletion
Rajendran V, Black J, Ardito T, Sangan P, Alper S, Schweinfest C, Kashgarian M, Binder H. Regulation of DRA and AE1 in rat colon by dietary Na depletion. AJP Gastrointestinal And Liver Physiology 2000, 279: g931-g942. PMID: 11052990, DOI: 10.1152/ajpgi.2000.279.5.g931.Peer-Reviewed Original Research
1994
A granulocyte inhibitory protein overexpressed in chronic renal disease regulates expression of interleukin 6 and interleukin 8.
Ziesche R, Roth M, Papakonstantinou E, Nauck M, Hörl W, Kashgarian M, Block L. A granulocyte inhibitory protein overexpressed in chronic renal disease regulates expression of interleukin 6 and interleukin 8. Proceedings Of The National Academy Of Sciences Of The United States Of America 1994, 91: 301-305. PMID: 8278382, PMCID: PMC42935, DOI: 10.1073/pnas.91.1.301.Peer-Reviewed Original ResearchConceptsGranulocyte inhibitory proteinsInterleukin-6Chronic renal diseaseChronic renal failureProgression of glomerulosclerosisHuman mesangial cellsInhibitory proteinPluripotential effectsRenal failureRenal diseaseCytokine expressionIL-6IL-8Interleukin-8Inflammatory reactionGIP resultsGlomerular responseMesangial cellsC-jun mRNAC-fos geneC-JunDe novo synthesisNovo synthesisExpressionOverall effect
1993
Expression of parathyroid hormone-related protein in the rat glomerulus and tubule during recovery from renal ischemia.
Soifer N, Van Why S, Ganz M, Kashgarian M, Siegel N, Stewart A. Expression of parathyroid hormone-related protein in the rat glomerulus and tubule during recovery from renal ischemia. Journal Of Clinical Investigation 1993, 92: 2850-2857. PMID: 8254039, PMCID: PMC288486, DOI: 10.1172/jci116905.Peer-Reviewed Original ResearchMeSH KeywordsActinsAmino Acid IsomerasesAnimalsBlotting, NorthernCarrier ProteinsGene ExpressionImmunohistochemistryIschemiaKidneyKidney GlomerulusKidney TubulesMaleParathyroid Hormone-Related ProteinPeptidylprolyl IsomeraseProtein BiosynthesisProteinsRatsRats, Sprague-DawleyReceptors, Parathyroid HormoneReference ValuesRenal ArteryReperfusionRNA, MessengerConceptsHormone-related proteinMesangial cellsTubular cellsAcute renal ischemic injuryBilateral renal artery occlusionMale Sprague-Dawley ratsParathyroid hormone-related proteinAutocrine/paracrine fashionPTHrP mRNA levelsRenal artery occlusionRenal ischemic injuryMRNA levelsSprague-Dawley ratsDistal tubular cellsSham-operated animalsCyclophilin mRNA levelsProximal tubular cellsLocalization of PTHrPCultured mesangial cellsLocal growth factorsAdult rat kidneyArtery occlusionGlomerular epithelial cellsRenal injuryIschemic injuryEffect of transforming growth factor-β on extracellular matrix productionby cultured rat mesangial cells
ISHIMURA E, MORII H, STERZEL R, KASHGARIAN M. Effect of transforming growth factor-β on extracellular matrix productionby cultured rat mesangial cells. 日本腎臓学会誌 1993, 35: 311-320. PMID: 8341006, DOI: 10.14842/jpnjnephrol1959.35.311.Peer-Reviewed Original ResearchConceptsNorthern blottingCultured rat mesangial cellsRat mesangial cellsCollagen IExtracellular matrix constituentsMesangial cellsGrowth factorEnzyme-linked immunoadsorbent assayGene expressionProtein productionSingle growth factorECM constituentsProtein synthesisGenetic expressionMatrix componentsLamininExpressionGlomerular remodelingECM accumulationTGF-beta administrationBlottingMRNA expressionMatrix constituentsCellsGlomerular injury
1992
The cardiac conduction system in the rat expresses the alpha 2 and alpha 3 isoforms of the Na+,K(+)-ATPase.
Zahler R, Brines M, Kashgarian M, Benz E, Gilmore-Hebert M. The cardiac conduction system in the rat expresses the alpha 2 and alpha 3 isoforms of the Na+,K(+)-ATPase. Proceedings Of The National Academy Of Sciences Of The United States Of America 1992, 89: 99-103. PMID: 1309618, PMCID: PMC48183, DOI: 10.1073/pnas.89.1.99.Peer-Reviewed Original ResearchConceptsAlpha 3 isoformAlpha 2Gene expression approachAlpha 1 isoformIsoform genesSpecific hybridization signalAlpha subunitSpecific expressionMembrane channelsSpecific membrane channelsHybridization signalsIsoformsWorking myocytesCardiac conduction systemExcitable tissuesSodium pumpGenesSubunitsATPaseTissueExpressionStrandsExtracellular matrix protein: gene expression and synthesis in cultured rat mesangial cells
ISHIMURA E, STERZEL R, MORII H, KASHGARIAN M. Extracellular matrix protein: gene expression and synthesis in cultured rat mesangial cells. 日本腎臓学会誌 1992, 34: 9-17. PMID: 1593802, DOI: 10.14842/jpnjnephrol1959.34.9.Peer-Reviewed Original ResearchConceptsGene expressionProtein synthesisExtracellular matrixNorthern blottingBasement membrane matrix componentsFetal calf serumCollagen IMesangial cellsMRNA expressionDNA amountSynthesis of ECMCellular confluenceECM productionCultured rat mesangial cellsMatrix componentsRat mesangial cellsExpressionLamininBlottingCellsCalf serumImmunocytochemical studyPrevious immunocytochemical studiesCIIIMRNA