2020
Perfusion change in benign prostatic hyperplasia before and after castration in a canine model: Contrast enhanced ultrasonography and CT perfusion study
Yoon S, Alfajaro M, Cho K, Choi U, Je H, Jung J, Jang Y, Choi J. Perfusion change in benign prostatic hyperplasia before and after castration in a canine model: Contrast enhanced ultrasonography and CT perfusion study. Theriogenology 2020, 156: 97-106. PMID: 32682181, DOI: 10.1016/j.theriogenology.2020.06.026.Peer-Reviewed Original ResearchConceptsBenign prostatic hyperplasiaContrast-enhanced ultrasonographyCT perfusionVascular changesArterial inflowProstatic hyperplasiaPerfusion changesBlood volumeNormal prostateDevelopment of BPHMild benign prostatic hyperplasiaDay 60Intraprostatic DHT levelsLevels of dihydrotestosteroneCT perfusion studyIntraprostatic dihydrotestosteroneBlood volume changesEffects of hormonesMajor etiologyProstatic volumeSerum testosteroneVenous outflowDHT levelsNormal dogsVenous parameters
2018
Rotavirus-Induced Early Activation of the RhoA/ROCK/MLC Signaling Pathway Mediates the Disruption of Tight Junctions in Polarized MDCK Cells
Soliman M, Cho E, Park J, Kim J, Alfajaro M, Baek Y, Kim D, Kang M, Park S, Cho K. Rotavirus-Induced Early Activation of the RhoA/ROCK/MLC Signaling Pathway Mediates the Disruption of Tight Junctions in Polarized MDCK Cells. Scientific Reports 2018, 8: 13931. PMID: 30224682, PMCID: PMC6141481, DOI: 10.1038/s41598-018-32352-y.Peer-Reviewed Original ResearchConceptsTJ protein distributionTJ integrityTJ proteinsTight junctionsIntestinal epithelial tight junctionsEarly disruptionMDCK cellsEpithelial tight junctionsPrecise molecular mechanismsBovine NCDVRotavirus strainsEarly activationParacellular permeabilityCellular receptorsPerijunctional actomyosin ringTransepithelial resistanceEntry portalReversible decreaseSignaling pathwaysInfectionCoreceptorHarmful factorsMolecular mechanismsPresent studyCellsBovine Nebovirus Interacts with a Wide Spectrum of Histo-Blood Group Antigens
Cho E, Soliman M, Alfajaro M, Kim J, Seo J, Park J, Kim D, Baek Y, Kang M, Park S, Le Pendu J, Cho K. Bovine Nebovirus Interacts with a Wide Spectrum of Histo-Blood Group Antigens. Journal Of Virology 2018, 92: 10.1128/jvi.02160-17. PMID: 29467317, PMCID: PMC5899197, DOI: 10.1128/jvi.02160-17.Peer-Reviewed Original ResearchConceptsFucose epitopesTerminal sialic acidHost speciesVirus-like particlesHisto-blood group antigensCell surface carbohydrate moietiesMammalian host speciesEnteric calicivirusesAttachment factorsSialic acidCultured cell linesBovine digestive tractSurface carbohydrate moietiesCell carbohydratesHost rangeType speciesViral generaHBGA recognitionCarbohydrate moietyBiochemical assaysSpecific enzymesCellular receptorsSynthetic histo-blood group antigensReplication cycleSpecies
2017
Use of computed tomography and minimum intensity projection in the detection of lobar pneumonia mimicking lung lobe torsion in a dog
Lee S, Cho K, Alfajaro M, Lee J, Yu D, Choi J. Use of computed tomography and minimum intensity projection in the detection of lobar pneumonia mimicking lung lobe torsion in a dog. Veterinary Radiology & Ultrasound 2017, 60: e48-e53. PMID: 29044898, DOI: 10.1111/vru.12565.Peer-Reviewed Original ResearchConceptsLung lobe torsionLobar pneumoniaMinimum intensity projectionRight middle lungEvidence of torsionIntensity projectionLung torsionMiddle lungVesicular emphysemaPulmonary diseasePleural effusionMinimum intensity projection techniqueAffected lobeHistological examinationBronchial treeDogsPneumoniaContrast enhancementTomographyCT imagesThoracotomyBronchusCoughingEffusionEmphysemaComparison of elastography, contrast-enhanced ultrasonography, and computed tomography for assessment of lesion margin after radiofrequency ablation in livers of healthy dogs.
Moon S, Park S, Lee S, Cheon B, Hong S, Cho H, Park J, Alfajaro M, Cho K, Woo D, Choi J. Comparison of elastography, contrast-enhanced ultrasonography, and computed tomography for assessment of lesion margin after radiofrequency ablation in livers of healthy dogs. American Journal Of Veterinary Research 2017, 78: 295-304. PMID: 28240959, DOI: 10.2460/ajvr.78.3.295.Peer-Reviewed Original ResearchConceptsRadiofrequency ablationContrast-enhanced ultrasonographyLesion sizeHealthy dogsAblation lesionsRFA procedureConventional ultrasonographyComparisons of elastographyLesion size determinationAcute changesContrast CTVenous phaseClear marginsNecropsy findingsLesion changesClinical relevanceDay 3Granulation tissueUltrasonographyAcoustic shadowingLiverDogsEnhanced CT imagesImaging modalitiesActual lesion size