2016
Pathogenesis of Korean SapelovirusA in piglets and chicks
Kim D, Kang M, Son K, Bak G, Park J, Hosmillo M, Seo J, Kim J, Alfajaro M, Soliman M, Baek Y, Cho E, Lee J, Kwon J, Choi J, Goodfellow I, Cho K. Pathogenesis of Korean SapelovirusA in piglets and chicks. Journal Of General Virology 2016, 97: 2566-2574. PMID: 27487773, PMCID: PMC5078829, DOI: 10.1099/jgv.0.000571.Peer-Reviewed Original ResearchConceptsExtra-intestinal organsHigher viral RNA levelsNon-suppurative myelitisViral RNA levelsReal-time reverse transcription PCRCells of pigsIntestinal pathologyReverse transcription-PCRViral antigensViral pathogenesisReproductive disordersSapelovirus APathogenesisPorcine sapelovirusVirus entryCultured cell linesRNA levelsEpithelial cellsTranscription-PCRFecal samplesPigletsPneumoniaCell linesSialic acidPathologyPorcine Sapelovirus Uses α2,3-Linked Sialic Acid on GD1a Ganglioside as a Receptor
Kim D, Son K, Koo K, Kim J, Alfajaro M, Park J, Hosmillo M, Soliman M, Baek Y, Cho E, Lee J, Kang M, Goodfellow I, Cho K. Porcine Sapelovirus Uses α2,3-Linked Sialic Acid on GD1a Ganglioside as a Receptor. Journal Of Virology 2016, 90: 4067-4077. PMID: 26865725, PMCID: PMC4810533, DOI: 10.1128/jvi.02449-15.Peer-Reviewed Original ResearchConceptsHisto-blood group antigensPorcine sapelovirusReproductive disordersSialic acidGroup antigensTerminal sialic acidSynthetic histo-blood group antigensEfficient drugsGlucosylceramide synthase inhibitorSynthase inhibitorLinkage-specific sialidasesInfectionGD1a gangliosidesReceptorsCell surface glycolipidsPneumoniaPolioencephalomyelitisTherapyCell surface carbohydratesAntigenGD1aHost cellsDisordersDrugsSapelovirus
2013
Molecular epidemiology of Korean porcine sapeloviruses
Son K, Kim D, Matthijnssens J, Kwon H, Park J, Hosmillo M, Alfajaro M, Ryu E, Kim J, Kang M, Cho K. Molecular epidemiology of Korean porcine sapeloviruses. Archives Of Virology 2013, 159: 1175-1180. PMID: 24232913, PMCID: PMC7087272, DOI: 10.1007/s00705-013-1901-6.Peer-Reviewed Original ResearchConceptsGenetic diversityPorcine sapelovirusPronounced genetic diversityVP1 geneDiarrhea fecal samplesPhylogenetic analysisPrimer pairsPSV infectionGenesPCR assaysDiversityRT-PCRKorean pigsSapelovirusFecal samplesMolecular epidemiologyDiarrhea samplesBacteriaInfectionEnteric virusesHigher proportionAssaysPigsStrains