1994
Effect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure
Steens R, Millar T, Xiaoling S, Biberdorf D, Buckle P, Ahmed M, Kryger M. Effect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure. Sleep 1994, 17: 61-68. PMID: 8191204, DOI: 10.1093/sleep/17.1.61.Peer-Reviewed Original ResearchConceptsStable congestive heart failureCheyne-Stokes respirationCongestive heart failureInhalation of CO2Heart failureSleep timeNocturnal arterial oxygen desaturationNight polysomnographic studiesArterial oxygen desaturationMovement sleep timeTotal sleep timeApnea indexOxygen desaturationMost patientsPolysomnographic studySleep latencySleep disruptionClinical significanceCardiac diseaseSleep structurePatientsNeurological diseasesNight 3Virtual abolitionShort duration
1993
A Developmental Study of the Dose-Response Curve of the Respiratory Sensory Reflex
Alvaro R, De Almeida V, Kwiatkowski K, Cates D, Kryger M, Rigatto H. A Developmental Study of the Dose-Response Curve of the Respiratory Sensory Reflex. American Journal Of Respiratory And Critical Care Medicine 1993, 148: 1013-1017. PMID: 8214918, DOI: 10.1164/ajrccm/148.4_pt_1.1013.Peer-Reviewed Original ResearchReview: Sleep in Heart Failure
Yamashiro Y, Kryger M. Review: Sleep in Heart Failure. Sleep 1993, 16: 513-523. PMID: 8235235, DOI: 10.1093/sleep/16.6.513.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1992
Polysomnography in Acutely III Intensive Care Unit Patients
Buckle P, Pouliot Z, Millar T, Kerr P, Kryger M. Polysomnography in Acutely III Intensive Care Unit Patients. CHEST Journal 1992, 102: 288-291. PMID: 1623769, DOI: 10.1378/chest.102.1.288.Peer-Reviewed Original ResearchConceptsCase reportDescriptive studyDouble-blind clinical trialIntensive care unit patientsStudy designCare unit patientsSeries of patientsCase report studySeries of casesUnit patientsCause of diseaseInvestigational protocolsClinical trialsClinical relevanceClinical researchReport studyChestGold standardPatientsReportPolysomnographyTherapyStudy
1991
Central sleep apnoea in congenital muscular dystrophy.
Kryger M, Steljes D, Yee W, Mate E, Smith S, Mahowald M. Central sleep apnoea in congenital muscular dystrophy. Journal Of Neurology Neurosurgery & Psychiatry 1991, 54: 710. PMID: 1940943, PMCID: PMC1014476, DOI: 10.1136/jnnp.54.8.710.Peer-Reviewed Original ResearchConceptsCentral sleep apnoeaSleep-disordered breathingCongenital muscular dystrophyMorning headachesSleep apnoeaNocturnal seizuresCongestive heart failureMuscular dystrophyPulmonary hypertensionClinical weaknessHeart failureExcessive daytimeNeuromuscular syndromeRespiratory dysfunctionNeuromuscular disordersApnoeaHeadacheSeizuresSymptomsBreathingDystrophyHypertensionDysfunctionSyndrome
1985
Sleep and Respiration: Terminology and Methodology
West P, Kryger M. Sleep and Respiration: Terminology and Methodology. Clinics In Chest Medicine 1985, 6: 691-712. PMID: 3936667, DOI: 10.1016/s0272-5231(21)00406-8.Chapters
1980
The Effect of Low Flow Oxygen Therapy on the Chemical Control of Ventilation in Patients with Hypoxemic COPD1–3
Fleetham J, Bradley C, Kryger M, Anthonisen N. The Effect of Low Flow Oxygen Therapy on the Chemical Control of Ventilation in Patients with Hypoxemic COPD1–3. American Journal Of Respiratory And Critical Care Medicine 1980, 122: 833-40. PMID: 6779682, DOI: 10.1164/arrd.1980.122.6.833.Peer-Reviewed Original ResearchMeSH KeywordsCarbon DioxideHumansHypoxiaLung Diseases, ObstructiveOxygen Inhalation TherapyRespirationTime FactorsConceptsChronic obstructive pulmonary diseaseHypoxemic chronic obstructive pulmonary diseaseOxygen therapyHypoxic responseLow-flow oxygen therapyCentral ventilatory driveFlow oxygen therapyNocturnal oxygen therapyObstructive pulmonary diseaseArterial O2 saturationNocturnal oxygenPulmonary diseaseSuch patientsVentilatory driveMinute ventilationInspiratory flowO2 saturationPatientsTherapyContinuous oxygenMonthsHypoxiaInitial responseHypoxemiaVentilation
1978
Excessive Polycythemia of High Altitude: Role of Ventilatory Drive and Lung Disease1–3
Kryger M, McCullough R, Doekel R, Collins D, Weil J, Grover R. Excessive Polycythemia of High Altitude: Role of Ventilatory Drive and Lung Disease1–3. American Journal Of Respiratory And Critical Care Medicine 1978, 118: 659-666. PMID: 707889, DOI: 10.1164/arrd.1978.118.4.659.Peer-Reviewed Original ResearchConceptsCause of hypoxemiaExcessive polycythemiaPolycythemic patientsTidal volumeNormal subjectsExcessive hypoxemiaChemical driveAbnormal breathing patternsAlveolar-arterial differenceSmall tidal volumesHigh-altitude residentsRespiratory QuestionnaireSpirometric featuresHypoxic depressionVentilatory driveLung diseaseControl subjectsVentilatory responseMinute ventilationNormal lungBreathing patternHypoxemiaPatientsPolycythemiaDead spaceTreatment of Excessive Polycythemia of High Altitude with Respiratory Stimulant Drugs1–3
Kryger M, McCullough R, Collins D, Scoggin C, Weil J, Grover R. Treatment of Excessive Polycythemia of High Altitude with Respiratory Stimulant Drugs1–3. American Journal Of Respiratory And Critical Care Medicine 1978, 117: 455-64. PMID: 629480, DOI: 10.1164/arrd.1978.117.3.455.Peer-Reviewed Original ResearchMeSH KeywordsAdultAltitudeCarbon DioxideHematocritHumansMaleMedroxyprogesteroneMiddle AgedOxygenPolycythemiaRespirationTidal VolumeConceptsMedroxyprogesterone acetateExcessive polycythemiaTidal volumeVentilatory responseArterial PCO2O2 saturationWeeks of therapyMonths of treatmentEffect of medroxyprogesteroneHypoxic ventilatory responseArterial O2 saturationNormal arterial PCO2Progestational agentsArterial PO2Normal lungStimulant effectsExcessive hypoxemiaPatientsMedroxyprogesteroneNormal valuesPolycythemiaDead spaceVentilationTherapyHematocritFamilial aspects of decreased hypoxic drive in endurance athletes
Scoggin C, Doekel R, Kryger M, Zwillich C, Weil J. Familial aspects of decreased hypoxic drive in endurance athletes. Journal Of Applied Physiology 1978, 44: 464-468. PMID: 632187, DOI: 10.1152/jappl.1978.44.3.464.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCarbon DioxideFemaleGenesHumansHypercapniaHypoxiaMaleRespirationSports MedicineConceptsVentilatory responseEndurance athletesLong-distance runnersHypoxic ventilatory responseUnexplained respiratory failureFamilies of patientsHypercapnic responseRespiratory failureVentilatory responsivenessEndurance athleticsHealthy parentsShape parameter ANonathletic controlsHypoxic responseHypoxiaSimilar extentFamilial aspectsHypercapniaConsequence of conditioningAthletesRecent studiesFamilial influencesRunnersResponsePatientsHypoventilation: consequences and management.
Zwillich C, Kryger M, Weil J. Hypoventilation: consequences and management. Advances In Internal Medicine 1978, 23: 287-306. PMID: 343542.Peer-Reviewed Original Research
1976
Depression of Hypoxic Ventilatory Response by Nitrous Oxide
Yacoub O, Doell D, Kryger M, Anthonisen N. Depression of Hypoxic Ventilatory Response by Nitrous Oxide. Anesthesiology 1976, 45: 385-389. PMID: 973689, DOI: 10.1097/00000542-197610000-00006.Peer-Reviewed Original ResearchExercise tolerance at 4 and 6 ATA.
Anthonisen N, Utz G, Kryger M, Urbanetti J. Exercise tolerance at 4 and 6 ATA. Undersea And Hyperbaric Medicine 1976, 3: 95-112. PMID: 951829.Peer-Reviewed Original ResearchConceptsDisturbance of consciousnessNormal male subjectsMaximum breathing capacityMaximum oxygen uptakeMaximum O2 uptakeO2 uptakeSevere dyspneaATA O2Bicycle exerciseLarge airwaysMinute ventilationHeavy exerciseHeart rateExercise levelsMale subjectsN2 narcosisRespiratory frequencyBreathing capacityCO2 retentionOxygen uptakeVentilationSubjectsATAExerciseCO2 output