2007
Safety of ramelteon in individuals with mild to moderate obstructive sleep apnea
Kryger M, Wang-Weigand S, Roth T. Safety of ramelteon in individuals with mild to moderate obstructive sleep apnea. Sleep And Breathing 2007, 11: 159-164. PMID: 17294232, DOI: 10.1007/s11325-006-0096-4.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaNext-day residual effectsApnea-hypopnea indexSleep apneaPost-sleep questionnaireAdverse eventsSelective MT1/MT2 receptor agonistMT1/MT2 receptor agonistMT2 receptor agonistSafety of ramelteonUrinary tract infectionArterial oxygen saturationControl of breathingRespiratory inductance plethysmographyRamelteon groupPlacebo groupTract infectionsCrossover studyWashout periodDepressant effectSleep QuestionnaireHypopneic eventsRespiratory effortInsomnia treatmentOxygen saturation
2001
Sleep complaints and restless legs syndrome in adult type 2 diabetics
Skomro R, Ludwig S, Salamon E, Kryger M. Sleep complaints and restless legs syndrome in adult type 2 diabetics. Sleep Medicine 2001, 2: 417-422. PMID: 14592391, DOI: 10.1016/s1389-9457(01)00110-1.Peer-Reviewed Original ResearchRestless legs syndromeAdult type 2 diabeticsType 2 diabeticsAdult diabeticsLegs syndromeSleep complaintsPresence of RLSPrevalence of RLSConsecutive type 2 diabetic patientsType 2 Adult DiabeticsType 2 diabetic patientsEpworth Sleepiness ScoreProportion of diabeticsCauses of insomniaHigh rateSensory polyneuropathyCreatinine levelsExcessive somnolenceDaytime somnolenceDiabetes mellitusDiabetic patientsHypnotic useSensory neuropathyDiabetes controlSleep Questionnaire
1995
Sleep complaints are common in a dialysis unit
Walker S, Fine A, Kryger M. Sleep complaints are common in a dialysis unit. American Journal Of Kidney Diseases 1995, 26: 751-756. PMID: 7485127, DOI: 10.1016/0272-6386(95)90438-7.Peer-Reviewed Original ResearchConceptsRestless legs syndromeSleep-wake complaintsSpecific sleep disordersCreatinine levelsDialysis patientsLegs syndromeSleep apneaUremic patientsFrequent awakeningsImpaired qualitySleep complaintsSleep QuestionnaireHemodialysis unitDaytime sleepinessDisturbed sleepMale genderDialysis unitsCaffeine intakeClinical significanceSleep disordersSleep problemsFrequent complaintPatientsSpecific complaintsActual prevalence