1993
A Developmental Study of the Dose-Response Curve of the Respiratory Sensory Reflex
Alvaro R, De Almeida V, Kwiatkowski K, Cates D, Kryger M, Rigatto H. A Developmental Study of the Dose-Response Curve of the Respiratory Sensory Reflex. American Journal Of Respiratory And Critical Care Medicine 1993, 148: 1013-1017. PMID: 8214918, DOI: 10.1164/ajrccm/148.4_pt_1.1013.Peer-Reviewed Original Research
1986
Alteration in Breathing Pattern with Progression of Chronic Obstructive Pulmonary Disease1,2
Loveridge B, West P, Kryger M, Anthonisen N. Alteration in Breathing Pattern with Progression of Chronic Obstructive Pulmonary Disease1,2. American Journal Of Respiratory And Critical Care Medicine 1986, 134: 930-934. PMID: 3777689, DOI: 10.1164/arrd.1986.134.5.930.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseRespiratory failureSevere groupBreathing patternRespiratory inductance plethysmographStable chronic obstructive pulmonary diseaseRespiratory failure groupChronic obstructive pulmonaryObstructive pulmonary diseaseSignificant decreaseVT/TISeverity of diseasePulmonary diseaseAcute reliefFailure groupSupplemental O2Minute ventilationVentilatory controlTidal volumeModerate groupMechanical abnormalitiesInductance plethysmographBreathing frequencySeated positionFEV1
1984
Breathing Patterns in Patients with Chronic Obstructive Pulmonary Disease1,2
Loveridge B, West P, Anthonisen N, Kryger M. Breathing Patterns in Patients with Chronic Obstructive Pulmonary Disease1,2. American Journal Of Respiratory And Critical Care Medicine 1984, 130: 730-3. PMID: 6497155, DOI: 10.1164/arrd.1984.130.5.730.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseCOPD groupRespiratory inductance plethysmographRib cageStable chronic obstructive pulmonary diseaseSex-matched control subjectsChronic obstructive pulmonaryObstructive pulmonary diseaseTi/TtotCOPD patientsMean PaO2Pulmonary diseaseControl subjectsMinute ventilationExpiratory timeInspiratory flowSitting positionTidal volumeNormal subjectsBreathing patternInductance plethysmographPatientsRespiratory cycleMean numberNeural control
1980
The Effect of Low Flow Oxygen Therapy on the Chemical Control of Ventilation in Patients with Hypoxemic COPD1–3
Fleetham J, Bradley C, Kryger M, Anthonisen N. The Effect of Low Flow Oxygen Therapy on the Chemical Control of Ventilation in Patients with Hypoxemic COPD1–3. American Journal Of Respiratory And Critical Care Medicine 1980, 122: 833-40. PMID: 6779682, DOI: 10.1164/arrd.1980.122.6.833.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseHypoxemic chronic obstructive pulmonary diseaseOxygen therapyHypoxic responseLow-flow oxygen therapyCentral ventilatory driveFlow oxygen therapyNocturnal oxygen therapyObstructive pulmonary diseaseArterial O2 saturationNocturnal oxygenPulmonary diseaseSuch patientsVentilatory driveMinute ventilationInspiratory flowO2 saturationPatientsTherapyContinuous oxygenMonthsHypoxiaInitial responseHypoxemiaVentilation
1978
Excessive Polycythemia of High Altitude: Role of Ventilatory Drive and Lung Disease1–3
Kryger M, McCullough R, Doekel R, Collins D, Weil J, Grover R. Excessive Polycythemia of High Altitude: Role of Ventilatory Drive and Lung Disease1–3. American Journal Of Respiratory And Critical Care Medicine 1978, 118: 659-666. PMID: 707889, DOI: 10.1164/arrd.1978.118.4.659.Peer-Reviewed Original ResearchConceptsCause of hypoxemiaExcessive polycythemiaPolycythemic patientsTidal volumeNormal subjectsExcessive hypoxemiaChemical driveAbnormal breathing patternsAlveolar-arterial differenceSmall tidal volumesHigh-altitude residentsRespiratory QuestionnaireSpirometric featuresHypoxic depressionVentilatory driveLung diseaseControl subjectsVentilatory responseMinute ventilationNormal lungBreathing patternHypoxemiaPatientsPolycythemiaDead space
1976
Exercise tolerance at 4 and 6 ATA.
Anthonisen N, Utz G, Kryger M, Urbanetti J. Exercise tolerance at 4 and 6 ATA. Undersea And Hyperbaric Medicine 1976, 3: 95-112. PMID: 951829.Peer-Reviewed Original ResearchConceptsDisturbance of consciousnessNormal male subjectsMaximum breathing capacityMaximum oxygen uptakeMaximum O2 uptakeO2 uptakeSevere dyspneaATA O2Bicycle exerciseLarge airwaysMinute ventilationHeavy exerciseHeart rateExercise levelsMale subjectsN2 narcosisRespiratory frequencyBreathing capacityCO2 retentionOxygen uptakeVentilationSubjectsATAExerciseCO2 output