2007
Roles for Drosophila melanogaster Myosin IB in Maintenance of Enterocyte Brush-Border Structure and Resistance to the Bacterial Pathogen Pseudomonas entomophila
Hegan PS, Mermall V, Tilney LG, Mooseker MS. Roles for Drosophila melanogaster Myosin IB in Maintenance of Enterocyte Brush-Border Structure and Resistance to the Bacterial Pathogen Pseudomonas entomophila. Molecular Biology Of The Cell 2007, 18: 4625-4636. PMID: 17855510, PMCID: PMC2043548, DOI: 10.1091/mbc.e07-02-0191.Peer-Reviewed Original ResearchConceptsMutant larvaePseudomonas entomophilaTail domainMyosin IBMidgut epithelial cellsActin filament coreDrosophila genomeApical brush borderMidgut enterocytesBrush borderCytoskeletal defectsLarval gutResponse pathwaysApical localizationMV membraneBrush border structureDeletion mutationsFood uptakeGram-negative bacterial infectionsInnate immune responseMyo1bGut physiologyEntomophilaEpithelial cellsMidgut
1999
Cloning and characterization of mouse brush border myosin‐I in adult and embryonic intestine
Skowron J, Mooseker M. Cloning and characterization of mouse brush border myosin‐I in adult and embryonic intestine. Journal Of Experimental Zoology 1999, 283: 242-257. PMID: 9933937, DOI: 10.1002/(sici)1097-010x(19990215)283:3<242::aid-jez3>3.0.co;2-f.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceBlotting, NorthernCell MembraneChickensCloning, MolecularEmbryonic and Fetal DevelopmentGene Expression Regulation, DevelopmentalHumansIntestinesMiceMicrovilliMolecular Sequence DataMyosinsRatsSequence Analysis, DNAConceptsBrush border myosinMicrovillar actin bundlesEmbryonic intestineSubcellular localization profileBasolateral membrane domainsGenomic clonesCalmodulin light chainsVertebrate speciesMembrane domainsActin corePlasma membraneKnockout strategiesActin bundlesImmunolocalization studiesIntestinal epithelial cellsGolgi apparatusNorthern analysisPrimary structureNorthern blotSitu localizationLocalization profilesRNA expressionEmbryosDirect targetingEmbryogenesis
1997
An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin
Frankel S, Sigel E, Craig C, Elgin S, Mooseker M, Artavanis-Tsakonas S. An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin. Journal Of Cell Science 1997, 110: 1999-2012. PMID: 9378752, DOI: 10.1242/jcs.110.17.1999.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsAntibodiesBacterial ProteinsCarrier ProteinsCell NucleusChromatinChromobox Protein Homolog 5Chromosomal Proteins, Non-HistoneChromosomesDrosophila melanogasterEmbryo, NonmammalianEuchromatinGene Expression Regulation, DevelopmentalGenes, InsectHeterochromatinMutagenesisNuclear ProteinsRatsConceptsHeterochromatin protein 1Actin-related proteinsPolytene chromosome spreadsLocalization patternsCentric heterochromatinChromosome spreadsEuchromatic bandsProtein 1Heterochromatin-mediated geneNuclear localization patternPericentric heterochromatinHeterochromatin functionChromatin structureNuclear functionsFunctional diversitySequence similarityPolytene nucleiArp4Larval tissuesPrepupal developmentGenetic evidenceMutant formsGenetic dataHeterochromatinCell cycle