2013
Immunoregulatory Neuropeptides
Ganea D, Skarica M. Immunoregulatory Neuropeptides. 2013, 144-160. DOI: 10.1002/9781118314814.ch7.Peer-Reviewed Original ResearchVasoactive intestinal peptideCentral nervous systemAnti-inflammatory neuropeptidesImmunoregulatory neuropeptideParasympathetic innervationAutoimmune diseasesImmunomodulatory roleIntestinal peptideImmune cellsLymphoid organsAdaptive immunityVivo effectsNervous systemImmune systemImmune sourcesClinical useNeuropeptidesMajor signaling pathwaysSignaling pathwaysPeptide familyReceptorsPleiotropic effectsInnervationChemokinesCytokines
2011
Novel mechanisms of immune modulation of natalizumab in multiple sclerosis patients
Skarica M, Eckstein C, Whartenby K, Calabresi P. Novel mechanisms of immune modulation of natalizumab in multiple sclerosis patients. Journal Of Neuroimmunology 2011, 235: 70-76. PMID: 21550672, DOI: 10.1016/j.jneuroim.2011.02.010.Peer-Reviewed Original ResearchConceptsNatalizumab therapyPeripheral bloodMonth timepointProportion of CD20Proportion of CD4Number of CD14Multiple sclerosis patientsImmune cell compositionHematopoetic stem cellsPercentage of cellsMechanism of actionNatalizumab treatmentRRMS patientsMS patientsNK cellsSclerosis patientsTreatment onsetCytokine productionImmune compositionImmune modulationImmune cellsT cellsB cellsPatientsTherapy