Marc Samsky, MD, FACC
he/him/his
Assistant ProfessorCards
About
Research
Publications
Featured Publications
American Heart Association Cardiogenic Shock Registry: Design and Implementation
Morrow D, Jessup M, Abraham W, Acker M, Aringo A, Batchelor W, Chikwe J, Costello S, Drakos S, Farmer S, Gelijns A, Gillette N, Hochman J, Isler M, Kapur N, Kilic A, Kormos R, Lewis E, Lindenfeld J, Lombardi P, Mancini D, Rao S, Rutan C, Samsky M, Krucoff M. American Heart Association Cardiogenic Shock Registry: Design and Implementation. Circulation Cardiovascular Quality And Outcomes 2024, 17: e010637. PMID: 38887950, DOI: 10.1161/circoutcomes.123.010637.Peer-Reviewed Original ResearchImprove quality of careQuality of careProcesses of careQuality improvement registryPragmatic randomized trialMonitoring of outcomesShock registryElectronic case record formPatient-level dataImplementation researchHealth systemImprovement registryCase record formClinical specialtiesParticipating hospitalsParticipating sitesIn-hospital survivalImprove qualityAssociational volunteeringRecord formCardiogenic shockRegistryPrecision medicine platformData structureComplications of heart diseaseSCAI SHOCK Stage Classification Expert Consensus Update: A Review and Incorporation of Validation Studies This statement was endorsed by the American College of Cardiology (ACC), American College of Emergency Physicians (ACEP), American Heart Association (AHA), European Society of Cardiology (ESC) Association for Acute Cardiovascular Care (ACVC), International Society for Heart and Lung Transplantation (ISHLT), Society of Critical Care Medicine (SCCM), and Society of Thoracic Surgeons (STS) in December 2021.
Naidu S, Baran D, Jentzer J, Hollenberg S, van Diepen S, Basir M, Grines C, Diercks D, Hall S, Kapur N, Kent W, Rao S, Samsky M, Thiele H, Truesdell A, Henry T. SCAI SHOCK Stage Classification Expert Consensus Update: A Review and Incorporation of Validation Studies This statement was endorsed by the American College of Cardiology (ACC), American College of Emergency Physicians (ACEP), American Heart Association (AHA), European Society of Cardiology (ESC) Association for Acute Cardiovascular Care (ACVC), International Society for Heart and Lung Transplantation (ISHLT), Society of Critical Care Medicine (SCCM), and Society of Thoracic Surgeons (STS) in December 2021. Journal Of The American College Of Cardiology 2022, 79: 933-946. PMID: 35115207, DOI: 10.1016/j.jacc.2022.01.018.Peer-Reviewed Original ResearchCardiogenic Shock After Acute Myocardial Infarction
Samsky M, Morrow D, Proudfoot A, Hochman J, Thiele H, Rao S. Cardiogenic Shock After Acute Myocardial Infarction. JAMA 2021, 326: 1840-1850. PMID: 34751704, PMCID: PMC9661446, DOI: 10.1001/jama.2021.18323.Peer-Reviewed Original ResearchCardiac safety research consortium “shock II” think tank report: Advancing practical approaches to generating evidence for the treatment of cardiogenic shock
Samsky M, Krucoff M, Morrow D, Abraham W, Aguel F, Althouse A, Chen E, Cigarroa J, DeVore A, Farb A, Gilchrist I, Henry T, Hochman J, Kapur N, Morrow V, Ohman E, O'Neill W, Piña I, Proudfoot A, Sapirstein J, Seltzer J, Senatore F, Shinnar M, Simonton C, Tehrani B, Thiele H, Truesdell A, Waksman R, Rao S. Cardiac safety research consortium “shock II” think tank report: Advancing practical approaches to generating evidence for the treatment of cardiogenic shock. American Heart Journal 2020, 230: 93-97. PMID: 33011148, PMCID: PMC7704747, DOI: 10.1016/j.ahj.2020.09.015.Peer-Reviewed Original ResearchTrends in Readmissions and Length of Stay for Patients Hospitalized With Heart Failure in Canada and the United States
Samsky M, Ambrosy A, Youngson E, Liang L, Kaul P, Hernandez A, Peterson E, McAlister F. Trends in Readmissions and Length of Stay for Patients Hospitalized With Heart Failure in Canada and the United States. JAMA Cardiology 2019, 4: 444-453. PMID: 30969316, PMCID: PMC6537806, DOI: 10.1001/jamacardio.2019.0766.Peer-Reviewed Original Research
2025
Hepatic Biomarker Abnormalities in the Cardiac Intensive Care Unit Proposed Criteria for Cardiohepatic Syndrome
Butt A, Padkins M, Crespo-Diaz R, Hillerson D, Katz J, Kamath P, Miller P, Rosenbaum A, Samsky M, Kashani K, Jentzer J. Hepatic Biomarker Abnormalities in the Cardiac Intensive Care Unit Proposed Criteria for Cardiohepatic Syndrome. JACC Advances 2025, 4: 101464. PMID: 39850044, PMCID: PMC11755386, DOI: 10.1016/j.jacadv.2024.101464.Peer-Reviewed Original ResearchCardiac intensive care unitLiver function testsIn-hospital mortalityLiver function test abnormalitiesAbnormal liver function testsCardiac intensive care unit patientsCardiac intensive care unit populationLFT valuesCardiohepatic syndromeCox proportional hazards regressionRisk prediction toolsAdmission liver function testsAssociated with higher in-hospital mortalityProportional hazards regressionAssociated with in-hospitalHistorical cohort studyHigher in-hospital mortalityEvaluate in-hospital mortalityOne-year mortalityPredictor of prognosisLiver synthetic dysfunctionIntensive care unitCohort studyHazards regressionLogistic regressionThe DanGer of Using Age to Decide About Using Microaxial Flow Pumps in Cardiogenic Shock
Samsky M, Kadosh B, Nanna M, Rao S. The DanGer of Using Age to Decide About Using Microaxial Flow Pumps in Cardiogenic Shock. Journal Of The American College Of Cardiology 2025, 85: 604-605. PMID: 39818661, DOI: 10.1016/j.jacc.2024.11.035.Peer-Reviewed Original ResearchLessons learned and future perspectives from the PRO-HF trial
Canonico M, Ambrosy A, Samsky M. Lessons learned and future perspectives from the PRO-HF trial. Heart Failure Reviews 2025, 1-3. PMID: 39794682, DOI: 10.1007/s10741-025-10482-6.Peer-Reviewed Original ResearchCardiohepatic Syndrome In The Cardiac Intensive Care Unit, One-year Mortality
Butt A, Padkins M, Crespo-Diaz R, Hillerson D, Katz J, Kamath P, Miller E, Rosenbaum A, Samsky M, Kashani K, Jentzer J. Cardiohepatic Syndrome In The Cardiac Intensive Care Unit, One-year Mortality. Journal Of Cardiac Failure 2025, 31: 196. DOI: 10.1016/j.cardfail.2024.10.045.Peer-Reviewed Original ResearchLiver function test abnormalitiesCardiac intensive care unitLiver function testsOne-year mortalityCardiac intensive care unit patientsAssociated with higher one-year mortalityCTCAE grade 1Cardiohepatic syndromeIntensive care unitTime of CICU admissionCICU patientsHazard ratioMultivariable adjustmentCTCAE gradeCICU admissionLFT valuesConfidence intervalsRisk of one-year mortalityPredictor of long-term prognosisAdmission liver function testsCox proportional hazards regressionCardiac intensive care unit admissionMeeting criteriaCare unitAbnormal liver function tests
2024
The Impact of Socioeconomic Status and Diagnostic Timeline on Clinical Outcomes in ATTR Cardiomyopathy
Chi K, Gallegos-Kattán C, Sikand N, Samsky M, Nanna M. The Impact of Socioeconomic Status and Diagnostic Timeline on Clinical Outcomes in ATTR Cardiomyopathy. Journal Of The American College Of Cardiology 2024, 84: e289-e290. PMID: 39505422, DOI: 10.1016/j.jacc.2024.07.050.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News
News
- April 01, 2024
Yale Faculty Present Groundbreaking Clinical Research at the 2024 American College of Cardiology Scientific Sessions
- September 14, 2023
Electronic Health Record Strategies Can Improve Care of Patients with Heart Failure
- July 10, 2023
Sarah Goldstein, MD: optimizing heart health in pregnant and postpartum women
- May 11, 2023
Discoveries & Impact (May 2023)
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Cardiovascular Medicine
Yale University, PO Box 208017
New Haven, Connecticut 06520-8017
United States