2023
Progesterone Attenuates the Stress Response in Individuals with Alcohol Dependence and Post-Traumatic Stress Disorder – A Pilot Study
Ralevski E, Newcomb J, Pisani E, DeNegre D, Peltier M, Jane J, Yoon G, Petrakis I. Progesterone Attenuates the Stress Response in Individuals with Alcohol Dependence and Post-Traumatic Stress Disorder – A Pilot Study. Journal Of Dual Diagnosis 2023, 20: 39-51. PMID: 38147491, PMCID: PMC11214330, DOI: 10.1080/15504263.2023.2294989.Peer-Reviewed Original ResearchAlcohol use disorderStress-induced cravingCognitive performanceNegative affectNeutral scriptsStress disorderPost-traumatic stress disorderComorbid alcohol use disorderTraumatic Stress DisorderMeasures of cravingCurrent alcohol use disorderPositive emotionsTrauma scriptsPhysiological measuresCravingStress-induced symptomsTest sessionsPTSDAnxietyAffectUse disordersLaboratory sessionsCocaine dependenceAlcohol dependenceIndividuals
2021
Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders
Peltier MR, Verplaetse TL, Mineur YS, Gueorguieva R, Petrakis I, Cosgrove KP, Picciotto MR, McKee SA. Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders. Neuropharmacology 2021, 187: 108499. PMID: 33600842, PMCID: PMC7992136, DOI: 10.1016/j.neuropharm.2021.108499.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsStress-related disordersAlcohol useMajor depressive disorderAlcohol-related disordersAlcohol use disorderPosttraumatic stress disorderStress regulation systemComplex comorbiditiesDepressive disorderProblematic alcohol useUse disordersAlcohol misuseTherapeutic potentialTrauma exposureSubstance abuseStress disorderAnxiety disordersDisordersExposure resultsProgestogensNeurosteroidsNegative affectWomenComorbiditiesMale counterparts
2018
Motivation and Readiness for Tobacco Cessation Among Nicotine Dependent Postmenopausal Females: A Pilot Study
Peltier MR, Roys MR, Waters AF, Vinci C, Waldo KM, Stewart SA, Toups RC, Jones L, Copeland AL. Motivation and Readiness for Tobacco Cessation Among Nicotine Dependent Postmenopausal Females: A Pilot Study. Experimental And Clinical Psychopharmacology 2018, 26: 125-131. PMID: 29648860, DOI: 10.1037/pha0000191.Peer-Reviewed Original ResearchConceptsMenopausal symptom severitySymptom severityWeight concernsBrief motivational interviewingCurrent pilot studyCessation treatmentPostmenopausal femalesPostmenopausal smokersMenopausal symptomsEstrogen productionAntiestrogenic effectsConsiderable health riskB-MISomatic symptomsSmokingPilot studyMotivational interviewingBaselineSeveritySymptomsHealth risksTreatmentNegative affectCessationLow levels