2017
Folate-mediated chemotherapy and diagnostics: An updated review and outlook
Xu L, Bai Q, Zhang X, Yang H. Folate-mediated chemotherapy and diagnostics: An updated review and outlook. Journal Of Controlled Release 2017, 252: 73-82. PMID: 28235591, PMCID: PMC5479736, DOI: 10.1016/j.jconrel.2017.02.023.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsFolate receptorCellular uptake mechanismVivo applicationsDiagnostic agentsNanomedicineNanoprobeTremendous effortsNanoparticlesMajor challengeClinical applicationAdministration routeDiagnosticsChemotherapyApplicationsHuman cancersLatest developmentsUptake mechanismPharmacokineticsConcise reviewRouteReview
2014
Semi-Interpenetrating Network (sIPN) Co-Electrospun Gelatin/Insulin Fiber Formulation for Transbuccal Insulin Delivery
Xu L, Sheybani N, Ren S, Bowlin GL, Yeudall WA, Yang H. Semi-Interpenetrating Network (sIPN) Co-Electrospun Gelatin/Insulin Fiber Formulation for Transbuccal Insulin Delivery. Pharmaceutical Research 2014, 32: 275-285. PMID: 25030186, DOI: 10.1007/s11095-014-1461-9.Peer-Reviewed Original ResearchConceptsMechanical propertiesPEG-DAModerate degradation rateDegradation ratePolyethylene glycol diacrylateScaffold formulationsFiber formulationsGlycol diacrylateSuitable formulationRelease kineticsSignificant enhancementSIPNsEosin YDrug deliveryInsulin deliveryNew formulationFormulationPermeabilityPropertiesCytocompatibilityFibersOil Red O stainingTransbuccal drug deliveryMethodsGelatinRed O staining