2017
Tip60 is associated with resistance to X‐ray irradiation in prostate cancer
Xie X, Xu Z, Wang C, Fang C, Zhao J, Xu L, Qian X, Dai J, Sun F, Xu D, He W. Tip60 is associated with resistance to X‐ray irradiation in prostate cancer. FEBS Open Bio 2017, 8: 271-278. PMID: 29435417, PMCID: PMC5794467, DOI: 10.1002/2211-5463.12371.Peer-Reviewed Original ResearchProstate cancerLNCaP cellsResponse of prostate cancerHuman prostate cancer cell linesHuman prostate cancer samplesProstate cancer cell linesSurvival of LNCaPProstate cancer patientsProstate cancer samplesAndrogen receptor translocationProstate cancer tissuesRadioresistance of prostate cancerExpression of Tip60Time-dependent mannerDepletion of Tip60Resistance to X-ray irradiationCancer cell linesAtaxia telangiectasia mutantSmall interfering RNAPredictive factorsRadiosensitive tissuesDU145 cellsCancer patientsReceptor translocationLNCaP
2012
Cytosolic sulfotransferase 2B1b promotes hepatocyte proliferation gene expression in vivo and in vitro
Zhang X, Bai Q, Xu L, Kakiyama G, Pandak WM, Zhang Z, Ren S. Cytosolic sulfotransferase 2B1b promotes hepatocyte proliferation gene expression in vivo and in vitro. AJP Gastrointestinal And Liver Physiology 2012, 303: g344-g355. PMID: 22679001, PMCID: PMC3423104, DOI: 10.1152/ajpgi.00403.2011.Peer-Reviewed Original ResearchConceptsLiver X receptorMouse liver tissueLiver tissueSulfotransferase 2B1bLiver proliferationPCNA-positive cellsPrimary rat hepatocytesCell nuclear antigenOxysterol sulfotransferaseWestern blot analysisCell cycle regulatory gene expressionProliferation gene expressionTime-dependent mannerGene expressionC57BL/6 miceQuantitative real-time PCRReal-time PCRLXR activationDouble immunofluorescenceLabeling indexSelective cholesterolAntiproliferative factorPCNA expressionLipid metabolismIncreased expression