Longitudinal biomonitoring of mycotoxin exposure during pregnancy in the Yale pregnancy Outcome Prediction study
Krausová M, Ayeni K, Gu Y, Borutzki Y, O’Bryan J, Perley L, Silasi M, Wisgrill L, Johnson C, Warth B. Longitudinal biomonitoring of mycotoxin exposure during pregnancy in the Yale pregnancy Outcome Prediction study. Environment International 2024, 109081. DOI: 10.1016/j.envint.2024.109081.Peer-Reviewed Original ResearchPregnancy Outcome Prediction studyPregnant womenOutcome prediction studiesTandem mass spectrometryLiquid chromatography tandem mass spectrometryPlasma matrixUrine methodMass spectrometryUrinary dataHuman biomonitoringCarcinogen ochratoxin ASerum methodNeoplastic effectsSerumLC-MS/MSMonomethyl etherUnborn childSerum samplesTime pointsUrineBiomarkers of exposurePregnancyAdverse health effectsWomenHuman biomonitoring guidance valuesNoninvasive single‐cell‐based prenatal genetic testing: A proof of concept clinical study
Bellair M, Amaral E, Ouren M, Roark C, Kim J, O'Connor A, Soriano A, Schindler M, Wapner R, Stone J, Tavella N, Merriam A, Perley L, Breman A, Beaudet A. Noninvasive single‐cell‐based prenatal genetic testing: A proof of concept clinical study. Prenatal Diagnosis 2024, 44: 304-316. PMID: 38411249, DOI: 10.1002/pd.6529.Peer-Reviewed Original ResearchConceptsNoninvasive prenatal genetic testingLow-risk pregnanciesConcept clinical studyCopy number analysisPrenatal genetic testingNext-generation sequencingPlacental mosaicismMaternal bloodAneuploidy resultsMeasures of test performanceCK stainingCVS casesClinical studiesGenetic testingNucleated cellsTrophoblastRed cellsNumber analysisPregnancyBloodDeletions/duplicationsAneuploidyDeletionAmniocentesisCells