Sustainability of Keratinocyte Gene Transfer and Cell Survival In Vivo
Choate K, Khavari P. Sustainability of Keratinocyte Gene Transfer and Cell Survival In Vivo. Human Gene Therapy 1997, 8: 895-901. PMID: 9195211, DOI: 10.1089/hum.1997.8.8-895.Peer-Reviewed Original ResearchConceptsGene deliveryCutaneous gene deliveryTherapeutic gene deliveryRetroviral vectorsNormal gene expression levelsBeta-gal expressionMultilayer epidermisGene transferRetroviral long terminal repeatEpidermal progenitor cellsSpecies-specific antibodiesVector sequencesCellular promotersKeratinocyte transglutaminaseDeliveryMarker gene expressionAttractive sitesGene productionType VII collagenHuman keratinocytesEfficiencyHuman involucrinTerminal repeat