2020
Circular RNA CircMAP3K5 Acts as a MicroRNA-22-3p Sponge to Promote Resolution of Intimal Hyperplasia Via TET2-Mediated Smooth Muscle Cell Differentiation
Zeng Z, Xia L, Fan S, Zheng J, Qin J, Fan X, Liu Y, Tao J, Liu Y, Li K, Ling Z, Bu Y, Martin KA, Hwa J, Liu R, Tang WH. Circular RNA CircMAP3K5 Acts as a MicroRNA-22-3p Sponge to Promote Resolution of Intimal Hyperplasia Via TET2-Mediated Smooth Muscle Cell Differentiation. Circulation 2020, 143: 354-371. PMID: 33207953, DOI: 10.1161/circulationaha.120.049715.Peer-Reviewed Original ResearchConceptsHuman coronary artery smooth muscle cellsTet2 knockout miceCoronary artery smooth muscle cellsArtery smooth muscle cellsCircular RNAsSmooth muscle cellsVascular smooth muscle cellsWire-injured mouse femoral arteriesSmooth muscle cell differentiationCircular RNA profilingMuscle cell differentiationRNA sequencing dataLoss of TET2Coronary heart diseaseVascular SMC differentiationMiR-22-3pPlatelet-derived growth factorKnockout miceSMC differentiationMaster regulatorRNA sequencingRNA profilingPlatelet-derived growth factor-BBGene expressionSequencing data
1997
Angiotensin II activates the beta 1 isoform of phospholipase C in vascular smooth muscle cells
Schelling J, Nkemere N, Konieczkowski M, Martin K, Dubyak G. Angiotensin II activates the beta 1 isoform of phospholipase C in vascular smooth muscle cells. American Journal Of Physiology 1997, 272: c1558-c1566. PMID: 9176147, DOI: 10.1152/ajpcell.1997.272.5.c1558.Peer-Reviewed Original ResearchConceptsAortic vascular smooth muscle cellsVascular smooth muscle cellsHuman aortic vascular smooth muscle cellsPLC-beta 1Ang IISmooth muscle cellsPLC beta isoformsPLC-beta 1 antibodyRat aortic vascular smooth muscle cellsPermeabilized vascular smooth muscle cellsMuscle cellsGrowth factorPathophysiology of hypertensionAngiotensin II receptorsIP formationReverse transcriptase-polymerase chain reactionPLC-gamma 1 antibodyTranscriptase-polymerase chain reactionPlatelet-derived growth factorCytosolic free Ca2Gamma 1 antibodiesAng II signalsAngiotensin IIAlpha antibodyII receptors