2024
Risk of Infection in Older Adults With Type 2 Diabetes With Relaxed Glycemic Control.
Lipska K, Gilliam L, Lee C, Liu J, Liu V, Moffet H, Parker M, Zapata H, Karter A. Risk of Infection in Older Adults With Type 2 Diabetes With Relaxed Glycemic Control. Diabetes Care 2024, 47: 2258-2265. PMID: 39436715, DOI: 10.2337/dc24-1612.Peer-Reviewed Original ResearchRisk of hospitalizationIncreased risk of hospitalizationType 2 diabetesRelative riskIntegrated health care delivery systemGlycemic controlHealth care delivery systemCare delivery systemOlder patientsBone infectionIncreased riskRelative risk of hospitalizationEstimated incidence rateGlycemic control levelsRates of hospitalizationRetrospective cohort studySoft tissueCategories of infectionOlder adultsUnadjusted riskClinical guidelinesRisk of infectionIncidence rateCohort studyNegative binomial modelWillingness to take less medication for type 2 diabetes among older patients: The Diabetes & Aging Study
Haider S, Parker M, Huang E, Grant R, Moffet H, Laiteerapong N, Jain R, Liu J, Lipska K, Karter A. Willingness to take less medication for type 2 diabetes among older patients: The Diabetes & Aging Study. Journal Of The American Geriatrics Society 2024, 72: 1985-1994. PMID: 38471959, PMCID: PMC11226366, DOI: 10.1111/jgs.18870.Peer-Reviewed Original ResearchAmerican Diabetes AssociationKaiser Permanente Northern California Diabetes RegistryOlder patientsDuration of diabetesPatient-clinician relationshipDe-intensify treatmentHealth status categoriesProportion of willingnessProportion of participantsGlucose-lowering medicationsDiabetes RegistrySurvey responses to questionsResponses to questionsOlder adultsHealth statusType 2 diabetesClinical guidelinesDiabetes medicationsStatus categoriesDiabetes AssociationOlder individualsAging StudyTreatment de-intensificationRandom sampleSurvey responses
2023
Glycemic control and diabetes complications across health status categories in older adults treated with insulin or insulin secretagogues: The Diabetes & Aging Study
Lipska K, Huang E, Liu J, Parker M, Laiteerapong N, Grant R, Moffet H, Karter A. Glycemic control and diabetes complications across health status categories in older adults treated with insulin or insulin secretagogues: The Diabetes & Aging Study. Journal Of The American Geriatrics Society 2023, 71: 3692-3700. PMID: 37638777, PMCID: PMC10872822, DOI: 10.1111/jgs.18565.Peer-Reviewed Original ResearchConceptsRisk of complicationsComplication riskPoor healthIntermediate healthOlder adultsGood healthRetrospective cohort studyEndocrine Society guidelinesIntegrated healthcare delivery systemType 2 diabetesProportional hazards modelHealth status categoriesHealthcare delivery systemMacrovascular eventsCohort studyGlycemic controlPrimary outcomeSevere hypoglycemiaSociety guidelinesClinical variablesInsulin secretagoguesHazards modelComplicationsCombined outcomeAging StudyThe Growing Role of Technology in the Care of Older Adults With Diabetes.
Huang E, Sinclair A, Conlin P, Cukierman-Yaffe T, Hirsch I, Huisingh-Scheetz M, Kahkoska A, Laffel L, Lee A, Lee S, Lipska K, Meneilly G, Pandya N, Peek M, Peters A, Pratley R, Sherifali D, Toschi E, Umpierrez G, Weinstock R, Munshi M. The Growing Role of Technology in the Care of Older Adults With Diabetes. Diabetes Care 2023, 46: 1455-1463. PMID: 37471606, PMCID: PMC10369127, DOI: 10.2337/dci23-0021.Peer-Reviewed Original ResearchConceptsOlder adultsAreas of careHealth care servicesDiabetes careContinuous glucose monitorEvidence-based technologiesDiabetes managementCare prioritiesClinical experienceClinical heterogeneityCare servicesDiabetesInsulin pumpCareScientific evidenceAdultsGlucose monitorDistinct subpopulationsCurrent knowledgeMajor barrierImportant populationPotential promiseCaregiversSevere hypoglycemia and falls in older adults with diabetes: The Diabetes & Aging Study
Moffet H, Huang E, Liu J, Parker M, Lipska K, Laiteerapong N, Grant R, Lee A, Karter A. Severe hypoglycemia and falls in older adults with diabetes: The Diabetes & Aging Study. Diabetes Epidemiology And Management 2023, 12: 100162. PMID: 37920602, PMCID: PMC10621321, DOI: 10.1016/j.deman.2023.100162.Peer-Reviewed Original ResearchSevere hypoglycemiaOlder adultsRisk of fallsCare-seeking behaviorLife-threatening eventsED visitsInpatient recordsPrevalence ratiosHypoglycemiaGreater prevalenceAge 65Clinical documentationDiabetesSample adultsAging StudyAdultsSurvey respondentsFallHospitalizationOutpatientsResearch designPrevalenceVisitsMonthsSeverity1356-P: Association of HbA1c with Diabetes Outcomes across Health Status Categories in Older Adults
LIPSKA K, HUANG E, LIU J, PARKER M, MOFFET H, GRANT R, LAITEERAPONG N, KARTER A. 1356-P: Association of HbA1c with Diabetes Outcomes across Health Status Categories in Older Adults. Diabetes 2023, 72 DOI: 10.2337/db23-1356-p.Peer-Reviewed Original ResearchComplication riskPoor healthIntermediate healthOlder adultsGood healthIntegrated healthcare delivery systemAssociation of HbA1cType 2 diabetesProportional hazards modelNational InstituteHealth status categoriesHealthcare delivery systemEligible patientsMacrovascular eventsSevere hypoglycemiaKidney diseaseClinical variablesDiabetes outcomesEndocrine SocietyAbbVie Inc.Hazards modelComplicationsHealth statusTwin healthPatientsDevelopment and Validation of the Life Expectancy Estimator for Older Adults with Diabetes (LEAD): the Diabetes and Aging Study
Karter A, Parker M, Moffet H, Lipska K, Laiteerapong N, Grant R, Lee C, Huang E. Development and Validation of the Life Expectancy Estimator for Older Adults with Diabetes (LEAD): the Diabetes and Aging Study. Journal Of General Internal Medicine 2023, 38: 2860-2869. PMID: 37254010, PMCID: PMC10228886, DOI: 10.1007/s11606-023-08219-y.Peer-Reviewed Original ResearchOlder adultsLife expectancyKaiser Permanente Northern CaliforniaRisk score toolLimited life expectancyClinical trial inclusionMortality prediction modelElectronic health recordsOlder patientsPatient characteristicsRetrospective cohortTrial inclusionAdvanced careCancer screeningClinical trialsTreatment goalsDiabetesSurvival analysisSurvival curvesLife expectancy modelCohortVital signsAging StudyHealth recordsKey ResultsInData‐driven classification of health status of older adults with diabetes: The diabetes and aging study
Huang E, Liu J, Lipska K, Grant R, Laiteerapong N, Moffet H, Schumm L, Karter A. Data‐driven classification of health status of older adults with diabetes: The diabetes and aging study. Journal Of The American Geriatrics Society 2023, 71: 2120-2130. PMID: 36883732, PMCID: PMC10363208, DOI: 10.1111/jgs.18310.Peer-Reviewed Original ResearchConceptsOlder adultsBaseline comorbiditiesCardiovascular eventsHigh prevalenceClass 3Integrated healthcare delivery systemRisk of complicationsType 2 diabetesClass 1Population health managementRace-adjusted ratesClass 2Healthcare delivery systemIncident complicationsCause mortalityMicrovascular eventsCohort studyComplication ratePrevalent comorbiditiesComorbid conditionsFuture complicationsHypoglycemic eventsDiabetes careCardiovascular conditionsLow prevalence