2013
The effect of selective amino acid supplementation on calcium absorption during a low protein diet
Bihuniak J, Sullivan R, Simpson C, Caseria D, O'Brien K, Kerstetter J, Insogna K. The effect of selective amino acid supplementation on calcium absorption during a low protein diet. The FASEB Journal 2013, 27: lb283-lb283. DOI: 10.1096/fasebj.27.1_supplement.lb283.Peer-Reviewed Original ResearchLow-protein dietIntestinal Ca absorptionCa absorptionProtein dietProtein intakeDietary protein intakeHigh-protein dietAmino acid supplementationCalcium absorptionAcid supplementationDay 5Dibasic amino acidsAA supplementationYoung womenControl dietRandom orderPhysiologic rangeDietary proteinIntakeDietSupplementationAmino acidsAromatic amino acidsCa economyLys supplementation
2011
Dietary protein increases intestinal calcium absorption in part by increasing tight junction expression of Claudin‐2
Gaffney‐Stomberg E, Cucchi C, Sun B, Bataille A, Renfro L, Kerstetter J, Insogna K. Dietary protein increases intestinal calcium absorption in part by increasing tight junction expression of Claudin‐2. The FASEB Journal 2011, 25: 983.30-983.30. DOI: 10.1096/fasebj.25.1_supplement.983.30.Peer-Reviewed Original ResearchHigh-protein dietCaco-2 BBe cellsClaudin-2 expressionCa absorptionCalcium absorptionProtein dietClaudin-2BBE cellsFemale Sprague-Dawley ratsIntestinal calcium absorptionDietary proteinSprague-Dawley ratsTight junction expressionCa transportTight junction proteinsTranscellular Ca transportDietary protein effectsCa-transporting proteinsDuodenal mucosaAcute effectsDay 7MRNA expressionJunction expressionJunction proteinsAmino acids
2010
The Effect of Dietary Protein on Intestinal Calcium Absorption in Rats
Gaffney-Stomberg E, Sun BH, Cucchi CE, Simpson CA, Gundberg C, Kerstetter JE, Insogna KL. The Effect of Dietary Protein on Intestinal Calcium Absorption in Rats. Endocrinology 2010, 151: 1071-1078. PMID: 20147526, PMCID: PMC2840679, DOI: 10.1210/en.2009-0744.Peer-Reviewed Original ResearchConceptsIntestinal Ca absorptionCa absorptionHigh-protein dietUrinary calciumBrush border membrane vesiclesProtein intakeFemale Sprague-Dawley ratsProtein dietProtein intake resultsIntestinal calcium absorptionDietary protein intakeHigh protein intakeSprague-Dawley ratsLow-protein groupHigh protein groupDietary protein effectsCalcium absorptionAcute increaseDawley ratsDuodenal mucosaIntake resultsRatsCa balanceTranscellular CaDietary protein
2009
A Rodent Model to Evaluate the Effect of Dietary Protein on Intestinal Calcium Absorption
Gaffney‐Stomberg E, Cucchi C, Sun B, Simpson C, Kerstetter J, Insogna K. A Rodent Model to Evaluate the Effect of Dietary Protein on Intestinal Calcium Absorption. The FASEB Journal 2009, 23: 726.1-726.1. DOI: 10.1096/fasebj.23.1_supplement.726.1.Peer-Reviewed Original ResearchHigh-protein dietLow-protein groupCa absorptionProtein dietBone turnoverBrush border membrane vesiclesIntestinal Ca absorptionIntestinal calcium absorptionDietary proteinVitamin D metabolitesLow protein intakeCa transportLow-protein dietSerum PTHSerum osteocalcinHr urineCalcium absorptionD metabolitesSerum CaDuodenal mucosaUrine CaRodent modelsAnimal modelsProtein intakeCa metabolism