2024
Effect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis
Hunter C, Marhoffer E, Holleck J, Alshaeba S, Grimshaw A, Chou A, Carey G, Gunderson C. Effect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis. Journal Of Antimicrobial Chemotherapy 2024, dkae422. PMID: 39656468, DOI: 10.1093/jac/dkae422.Peer-Reviewed Original ResearchPrevalence of P. aeruginosaEffects of empiric antibioticsEmpirical antibioticsUrinary tract infectionSoft tissue infectionsCommunity-acquired pneumoniaTract infectionsTissue infectionsP. aeruginosaMortality benefitHospitalized patientsPseudomonas aeruginosaPooled adjusted ORP. aeruginosa infectionType of infectionStudy of patientsAbsolute mortality benefitIntensive care settingSystematic literature searchNosocomial pneumoniaSeptic shockMeaningful benefitAdjusted ORWeb of ScienceCompare mortality ratesRisk of Serious Adverse Gastrointestinal Events with Potassium Binders in Hospitalized Patients: A National Study
Holleck J, Han L, Skanderson M, Bastian L, Gunderson C, Brandt C, Perkal M, Chang J, Akgün K. Risk of Serious Adverse Gastrointestinal Events with Potassium Binders in Hospitalized Patients: A National Study. Journal Of General Internal Medicine 2024, 1-7. PMID: 39103605, DOI: 10.1007/s11606-024-08979-1.Peer-Reviewed Original ResearchAdjusted odds ratiosSodium zirconium cyclosilicateU.S. Department of Veterans Affairs healthcare systemDepartment of Veterans Affairs healthcare systemVA Corporate Data WarehouseVeterans Affairs Healthcare SystemCorporate Data WarehousePotassium bindersHospitalized patientsGI eventsHealthcare systemOdds ratioAdverse GI eventsSodium polystyrene sulfonateNational studyPotassium-binding drugsComparative riskAdverse gastrointestinal eventsGI adverse eventsTreatment of hyperkalemiaZirconium cyclosilicateGastrointestinal eventsPatiromerAdverse events
2023
Reducing Nighttime Interruptions and Improving Sleep for Hospitalized Patients by Restructuring Nighttime Clinical Workflow
Holleck M, Tikkanen K, Holleck J, Frank C, Falco N, Cosentino D, Chang J. Reducing Nighttime Interruptions and Improving Sleep for Hospitalized Patients by Restructuring Nighttime Clinical Workflow. Journal Of General Internal Medicine 2023, 38: 2091-2097. PMID: 36697927, PMCID: PMC10361944, DOI: 10.1007/s11606-022-08005-2.Peer-Reviewed Original ResearchConceptsBlood pressure checkPressure checkHospitalized patientsSleep disruptionClinical workflowNighttime sleep disruptionsVenous thromboembolism prophylaxisGeneral medical wardsPercentage of patientsCross-sectional studyVeterans Administration HospitalWorse sleep qualityKey ResultsAfterNocturnal disruptionsTelemetry patientsThromboembolism prophylaxisMedical wardsImproved sleepMedication administrationAdministration HospitalSleep qualityPatientsNighttime disruptionsSleep surveyHospital