2017
A measurement-based generalized source model for Monte Carlo dose simulations of CT scans
Ming X, Feng Y, Liu R, Yang C, Zhou L, Zhai H, Deng J. A measurement-based generalized source model for Monte Carlo dose simulations of CT scans. Physics In Medicine And Biology 2017, 62: 1759-1776. PMID: 28079526, PMCID: PMC5857954, DOI: 10.1088/1361-6560/aa5911.Peer-Reviewed Original ResearchConceptsMonte Carlo dose simulationsGeneralized source modelEnergy spectrumFluence distributionDose profilesCentral axis percent depth dose curvePercent depth dose curvesDose simulationsDepth dose curvesMonte Carlo user codeSource distributionBeam inputDose curvesFilm measurementsCTDI phantomCT scannerOutput factorsAbsolute dose comparisonsMonte Carlo simulationsDose distributionSource modelCarlo simulationsCircular sourceGE LightspeedScanner specifications
2015
Intermediate Megavoltage Photon Beams for Improved Lung Cancer Treatments
Zhang Y, Feng Y, Ahmad M, Ming X, Zhou L, Deng J. Intermediate Megavoltage Photon Beams for Improved Lung Cancer Treatments. PLOS ONE 2015, 10: e0145117. PMID: 26672752, PMCID: PMC4682946, DOI: 10.1371/journal.pone.0145117.Peer-Reviewed Original ResearchConceptsDosimetric benefitsPotential dosimetric benefitsTarget coverageComparable target coverageLung cancer patientsLung cancer treatmentBetter target coverageCurrent treatment approachesImproved tumor coverageNormal tissue dosesTumor dose coverageLung cancer radiotherapyAdjacent critical structuresCritical structuresLung doseCancer patientsLung cancerThin patientsLung volumeLung tumorsDose coverageTreatment approachesPatientsReduced dosesTumor coverage
2007
On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy
Chen ZJ, Deng J, Roberts K, Nath R. On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy. International Journal Of Radiation Oncology • Biology • Physics 2007, 70: 303-310. PMID: 17980500, PMCID: PMC2289996, DOI: 10.1016/j.ijrobp.2007.09.007.Peer-Reviewed Original ResearchConceptsDose reductionProstate brachytherapyDose compensationLarge edemaBiochemical recurrence-free survivalRecurrence-free survivalSignificant dose reductionEffects of edemaSublethal damage repairAdditional irradiationPrescription doseProstate cancerIndividual patientsEdemaEdema evolutionPrescribed doseProstate edemaEffective doseRadiobiologic effectsBrachytherapyDoseProstate implantsDose responseImplants
2001
Derivation of electron and photon energy spectra from electron beam central axis depth dose curves
Deng J, Jiang S, Pawlicki T, Li J, Ma C. Derivation of electron and photon energy spectra from electron beam central axis depth dose curves. Physics In Medicine And Biology 2001, 46: 1429-1449. PMID: 11384063, DOI: 10.1088/0031-9155/46/5/308.Peer-Reviewed Original ResearchConceptsPhoton energy spectrumDepth dose curvesCentral axis depth dose curvesPhase-space simulationsElectron beamEnergy spectrumDose curvesElectron beam dose calculationsLinear accelerator treatment headCentral axis percentage depth-dose (PDD) curvesPercentage depth dose curvesDerivation of electronPhase space dataClinical electron beamsMeV electron beamSpace simulationTreatment headPDD curvesDose profilesElectronsBeamCorresponding spectraPhotonsDose calculationsSpectra
2000
Energy- and intensity-modulated electron beams for radiotherapy
Ma C, Pawlicki T, Lee MC, Jiang SB, Li JS, Deng J, Yi B, Mok E, Boyer AL. Energy- and intensity-modulated electron beams for radiotherapy. Physics In Medicine And Biology 2000, 45: 2293-2311. PMID: 10958195, DOI: 10.1088/0031-9155/45/8/316.Peer-Reviewed Original ResearchConceptsModulated electron radiotherapyIntensity-modulated electron beamElectron beamMultileaf collimatorElectron beam energyInter-leaf leakageDose distributionElectron intraMonte Carlo dose calculationsPencil beam algorithmLeaf endsBeam energyPhoton beamsElectron radiotherapyOblique incidencePatient surfaceMonte Carlo methodBeamBeam algorithmField shapeMonte Carlo simulationsDose calculationsSuperficial targetsCarlo methodCarlo simulations