2024
Cognitive Motor Dissociation in Disorders of Consciousness
Bodien Y, Allanson J, Cardone P, Bonhomme A, Carmona J, Chatelle C, Chennu S, Conte M, Dehaene S, Finoia P, Heinonen G, Hersh J, Kamau E, Lawrence P, Lupson V, Meydan A, Rohaut B, Sanders W, Sitt J, Soddu A, Valente M, Velazquez A, Voss H, Vrosgou A, Claassen J, Edlow B, Fins J, Gosseries O, Laureys S, Menon D, Naccache L, Owen A, Pickard J, Stamatakis E, Thibaut A, Victor J, Giacino J, Bagiella E, Schiff N. Cognitive Motor Dissociation in Disorders of Consciousness. New England Journal Of Medicine 2024, 391: 598-608. PMID: 39141852, DOI: 10.1056/nejmoa2400645.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingTask-based fMRICognitive motor dissociationDisorders of consciousnessComa Recovery Scale-RevisedCognitive tasksMotor dissociationObserved responseBrain injuryVerbal commandsBrain traumaScale-RevisedMagnetic resonance imagingDisordersBrainParticipantsEtiological factorsAssociated with younger ageElectroencephalographyCohort of personsResonance imagingProspective cohort studyTaskElectroencephalography dataMedian age
2023
Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study
Schiff N, Giacino J, Butson C, Choi E, Baker J, O’Sullivan K, Janson A, Bergin M, Bronte-Stewart H, Chua J, DeGeorge L, Dikmen S, Fogarty A, Gerber L, Krel M, Maldonado J, Radovan M, Shah S, Su J, Temkin N, Tourdias T, Victor J, Waters A, Kolakowsky-Hayner S, Fins J, Machado A, Rutt B, Henderson J. Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study. Nature Medicine 2023, 29: 3162-3174. PMID: 38049620, PMCID: PMC11087147, DOI: 10.1038/s41591-023-02638-4.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryDeep brain stimulationExecutive controlProcessing speedBrain stimulationImprove executive controlCentral lateral (CL) nucleusTrail-Making TestChronic phase of recoveryBrain injuryYears post-injuryFrontostriatal networkEfficacy of deep brain stimulationExecutive functionConverging evidenceLimit quality of lifeEfficacy measuresMsTBIPhase of recoveryPost-injuryRandomized feasibility studyThalamic deep brain stimulationQuality of lifeParticipantsProtocol non-compliance
2022
Cognitive-Motor Dissociation Following Pediatric Brain Injury
Kim N, O'Sullivan J, Olafson E, Caliendo E, Nowak S, Voss H, Lowder R, Watson W, Ivanidze J, Fins J, Schiff N, Hill N, Shah S. Cognitive-Motor Dissociation Following Pediatric Brain Injury. Neurology Clinical Practice 2022, 12: 248-257. PMID: 35733619, PMCID: PMC9208423, DOI: 10.1212/cpj.0000000000001169.Peer-Reviewed Original ResearchCognitive-motor dissociationCognitive functionParticipants' EEGSemantic processing of wordsCovert cognitionBrain injuryProcessing of wordsIntact semantic processingIdentifying such personsResponses to auditory stimuliDiverse batteryCognitive abilitiesMinimally conscious stateCognitive-motorCognitive capacityPediatric brain injuryCommunication attemptsAuditory stimuliAged 9CognitionNeuroimagingMotor outputConscious stateParticipantsBrain
2018
Disorders of Consciousness, Agency, and Health Care Decision Making: Lessons From a Developmental Model
Wright M, Kraft C, Ulrich M, Fins J. Disorders of Consciousness, Agency, and Health Care Decision Making: Lessons From a Developmental Model. AJOB Neuroscience 2018, 9: 56-64. DOI: 10.1080/21507740.2018.1425755.Peer-Reviewed Original ResearchDisorders of consciousnessHealth care decision makingCare decision makingLegal systemPermanent incapacitySelf-determinationHealthDevelopmental modelDecision-making frameworkDecisionIncreasing roleDisordersPatientsPatient evolutionDecision makingRecovery processIncapacityPersonhoodPhysiciansAgenciesDisabilityMaximal extentParticipants
2017
Guardianship and Clinical Research Participation: The Case of Wards with Disorders of Consciousness
Wright M, Ulrich M, Fins J. Guardianship and Clinical Research Participation: The Case of Wards with Disorders of Consciousness. Kennedy Institute Of Ethics Journal 2017, 27: 43-70. PMID: 28366903, DOI: 10.1353/ken.2017.0003.Peer-Reviewed Original ResearchConceptsState guardianship lawsGuardianship lawsAppointment of guardiansDecision-making authorityFederal lawGuardian's authorityState lawsClinical research participationDecisional capacityLawPotential medical interventionsDisorders of consciousnessGuardiansResearch participantsBehalfPatient accessAuthorsMedical interventionsGuardianshipStateAppointmentPersonsResearchIssuesParticipants
2012
Learning by Doing: Effectively Incorporating Ethics Education into Residency Training
Vertrees S, Shuman A, Fins J. Learning by Doing: Effectively Incorporating Ethics Education into Residency Training. Journal Of General Internal Medicine 2012, 28: 578-582. PMID: 23179971, PMCID: PMC3599016, DOI: 10.1007/s11606-012-2277-0.Peer-Reviewed Original ResearchConceptsSurrogate decision-makersRefusal of treatmentEducational initiativesDidactic programEthics educationMedical ethicsEthics casesMedical futilityEthical issuesEthicsExperiential education programParticipants' experiencesGood/very goodSubscale scoresClinical traineesResidency trainingEducation programsClinical experienceResidentsStudent Evaluation of Educational QualityParticipantsCourse surveyGroup interactionProgramBreadth of coverage
2007
Late recovery from the minimally conscious state
Fins J, Schiff N, Foley K. Late recovery from the minimally conscious state. Neurology 2007, 68: 304-307. PMID: 17242341, DOI: 10.1212/01.wnl.0000252376.43779.96.Peer-Reviewed Original ResearchConceptsMinimally conscious stateDisorders of consciousnessDiagnosis of persistent vegetative stateLate recoveryInvestigation of patientsPersistent vegetative stateConscious statePrognostic markerTraumatic injuryPublic confusionMeeting participantsResearch initiativesDiagnostic testsAxonal regrowthPublished studiesParticipantsPatientsMechanisms of recoveryVegetative stateMeetingInitial focus
2003
Reflective Practice and Palliative Care Education
Fins J, Gentilesco B, Carver A, Lister P, Acres C, Payne R, Storey-Johnson C. Reflective Practice and Palliative Care Education. Academic Medicine 2003, 78: 307-312. PMID: 12634214, DOI: 10.1097/00001888-200303000-00015.Peer-Reviewed Original ResearchConceptsSymptom managementPatient carePalliative care educationContext of careEnd of lifeTwo-week clerkshipMethods of painParticipant observationPalliative careCare educationInfluence careReflective practiceCareMedical studentsPractice patternsClerkshipClinical ethicsHidden curriculumDimensions of practiceContextual factorsTherapeutic skillsHumanistic mannerShort-term evaluationHumanistic dimensionParticipants
1991
University medical center participation in residency training programs for graduates of foreign medical schools.
Bogdonoff M, Fins J. University medical center participation in residency training programs for graduates of foreign medical schools. Annals Of Internal Medicine 1991, 114: 426-7. PMID: 1992886, DOI: 10.7326/0003-4819-114-5-426.Peer-Reviewed Original Research