2022
Cognitive-Motor Dissociation Following Pediatric Brain Injury
Kim N, O'Sullivan J, Olafson E, Caliendo E, Nowak S, Voss H, Lowder R, Watson W, Ivanidze J, Fins J, Schiff N, Hill N, Shah S. Cognitive-Motor Dissociation Following Pediatric Brain Injury. Neurology Clinical Practice 2022, 12: 248-257. PMID: 35733619, PMCID: PMC9208423, DOI: 10.1212/cpj.0000000000001169.Peer-Reviewed Original ResearchCognitive-motor dissociationCognitive functionParticipants' EEGSemantic processing of wordsCovert cognitionBrain injuryProcessing of wordsIntact semantic processingIdentifying such personsResponses to auditory stimuliDiverse batteryCognitive abilitiesMinimally conscious stateCognitive-motorCognitive capacityPediatric brain injuryCommunication attemptsAuditory stimuliAged 9CognitionNeuroimagingMotor outputConscious stateParticipantsBrainDisorders of Consciousness, Disability Rights, and Triage During the Covid-19 Pandemic
Fins J. Disorders of Consciousness, Disability Rights, and Triage During the Covid-19 Pandemic. 2022, 191-202. DOI: 10.4324/9781003289487-25.Peer-Reviewed Original Research
2019
Disorders of Consciousness, Past, Present, and Future
Fins J. Disorders of Consciousness, Past, Present, and Future. Cambridge Quarterly Of Healthcare Ethics 2019, 28: 603-615. PMID: 31405394, DOI: 10.1017/s0963180119000719.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessLegal obligationsPersistent vegetative stateConsciousness literatureNational Institute on DisabilityCognitive motor dissociationMinimally conscious stateCounter-narrativesAmerican Academy of NeurologyVegetative stateMotor dissociationCovert consciousnessObligationsConscious stateDisordersIndependent livingStateDisorders of Consciousness in Clinical Practice
Fins J. Disorders of Consciousness in Clinical Practice. 2019, 449-478. DOI: 10.1093/med/9780190208875.003.0011.Peer-Reviewed Original ResearchEnd-of-life careEnd-of-lifeLong-term careImpaired decision-making capacityDisorders of consciousnessClinical practiceDecision-making capacityAncillary care obligationsVulnerable populationsProfessional obligationsCareMinimally conscious stateNeuroimaging assessmentsIntensive careCare obligationsDiagnostic classificationBrain injuryCommunication strategiesCovert consciousnessClinicInitial presentationConscious stateEthical implicationsPatientsRehabilitationOnce and Future Clinical Neuroethics: A History of What Was and What Might Be.
Fins J. Once and Future Clinical Neuroethics: A History of What Was and What Might Be. The Journal Of Clinical Ethics 2019, 30: 27-34. PMID: 30896441, DOI: 10.1086/jce2019301027.Peer-Reviewed Original Research
2016
Neuroethics and Disorders of Consciousness: Discerning Brain States in Clinical Practice and Research
Fins J. Neuroethics and Disorders of Consciousness: Discerning Brain States in Clinical Practice and Research. The AMA Journal Of Ethic 2016, 18: 1182. PMID: 28009244, DOI: 10.1001/journalofethics.2016.18.12.ecas2-1612.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessMinimally conscious stateEnd-of-life careConscious stateEnd-of-lifeEthical obligationNeuropalliative careDeep brain stimulationPatientsBrain statesClinicians' ethical obligationsClinical practiceCivil rightsConsciousnessScientific advancesDiagnostic discernmentClinical researchBrain stimulationResearch decisionsDisordersFunctional communicationInvestigate useCareNeuroethicsPainBrain death and disorders of consciousness
Schiff N, Fins J. Brain death and disorders of consciousness. Current Biology 2016, 26: r572-r576. PMID: 27404252, DOI: 10.1016/j.cub.2016.02.027.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessBrain-dead patientsBrain deathVegetative stateCognitive motor dissociationScientific knowledgeCognitive functionMinimally conscious stateNon-medical specialistsSocietal contextBrain statesConsciousnessConscious stateMotor dissociationBrainDisordersDead patientsConceptual frameworkLack of sustainabilityHigher levelsFutilityParadoxDistinction
2015
Rights Come to Mind
Fins J. Rights Come to Mind. 2015 DOI: 10.1017/cbo9781139051279.Peer-Reviewed Original ResearchNeuro-palliative care and disorders of consciousness
Fins J, Pohl B. Neuro-palliative care and disorders of consciousness. 2015, 285-291. DOI: 10.1093/med/9780199656097.003.0103.Peer-Reviewed Original ResearchPalliative care expertiseMinimally conscious stateBrain injuryPalliative carePalliative medicineCare expertiseCareDisorders of consciousnessConscious stateDefinition criteriaNihilistic attitudeInjuryPatientsDistressInterventionSurvivorsTherapeutic interventionsCliniciansDisordersNeuroprosthetic devicesSufferingMedicineAttitudes
2013
Disorders of Consciousness Following Severe Brain Injury
Fins J, Schiff N. Disorders of Consciousness Following Severe Brain Injury. 2013, 162-174. DOI: 10.1093/acprof:oso/9780195389784.003.0013.Peer-Reviewed Original ResearchDisorders of consciousnessBrain statesInterviews of familiesTraditional nosologyBehavioral measuresFunctional communicationMinimally conscious stateNeuroimaging dataDiagnostic classificationMeasures of assessmentBrain injuryDisordersConscious stateBrainFamily experiencesClinical practiceNeuroimagingNosology
2012
Central Thalamic Deep Brain Stimulation to Promote Recovery from Chronic Posttraumatic Minimally Conscious State: Challenges and Opportunities
Giacino J, Fins J, Machado A, Schiff N. Central Thalamic Deep Brain Stimulation to Promote Recovery from Chronic Posttraumatic Minimally Conscious State: Challenges and Opportunities. Neuromodulation Technology At The Neural Interface 2012, 15: 339-349. PMID: 22624587, DOI: 10.1111/j.1525-1403.2012.00458.x.Peer-Reviewed Original ResearchMeSH KeywordsBrain InjuriesBrain MappingClinical Trials as TopicDeep Brain StimulationElectrodes, ImplantedHumansInformed ConsentMonitoring, IntraoperativeNeuronavigationNeurosurgical ProceduresPatient Care PlanningPatient SelectionPersistent Vegetative StatePostoperative CareRecovery of FunctionThalamusConceptsTraumatic brain injuryCentral thalamic deep brain stimulationCT-DBSMinimally conscious stateThalamic deep brain stimulationOutcome measuresDeep brain stimulationSecondary outcome measuresIncreased functional communicationChronic minimally conscious stateBrain stimulationComa Recovery Scale-RevisedSingle-subject studySevere traumatic brain injuryImproved behavioral functionFunctional independenceObject namingWorking memoryConscious stateSustained attentionScale-RevisedBehavioral functionsFunctional communicationModulate arousalCentral thalamus
2011
Neuroethics, neuroimaging, and disorders of consciousness: promise or peril?
Fins J. Neuroethics, neuroimaging, and disorders of consciousness: promise or peril? Transactions Of The American Clinical And Climatological Association 2011, 122: 336-46. PMID: 21686236, PMCID: PMC3116331.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingDisorders of consciousnessPositron emission tomographyBehavior-based assessmentsMinimally conscious stateNeuroimaging dataNeuroimaging toolsBrain statesBrain injuryMagnetic resonance imagingNeuroimagingEmission tomographyConscious stateDisordersBrainResonance imagingNeuroimaging applicationsConsciousnessDiagnostic dilemmaTherapeutic useCommunication vectorNeuroethics
2010
Conflicts of interest in deep brain stimulation research and the ethics of transparency.
Fins J, Schiff N. Conflicts of interest in deep brain stimulation research and the ethics of transparency. The Journal Of Clinical Ethics 2010, 21: 125-32. PMID: 20866018, DOI: 10.1086/jce201021205.Peer-Reviewed Original Research
2009
Deep Brain Stimulation, Neuroethics, and the Minimally Conscious State: Moving Beyond Proof of Principle
Schiff N, Giacino J, Fins J. Deep Brain Stimulation, Neuroethics, and the Minimally Conscious State: Moving Beyond Proof of Principle. JAMA Neurology 2009, 66: 697-702. PMID: 19506129, DOI: 10.1001/archneurol.2009.79.Peer-Reviewed Original ResearchThe ethics of measuring and modulating consciousness: the imperative of minding time
Fins J. The ethics of measuring and modulating consciousness: the imperative of minding time. Progress In Brain Research 2009, 177: 371-382. PMID: 19818915, DOI: 10.1016/s0079-6123(09)17726-9.Peer-Reviewed Original ResearchConceptsMinimally conscious stateDisorders of consciousnessConscious stateView of timeHistory of medicineOver-arching metaphorModulate consciousnessFunctional neuroimagingScientific knowledgeSocial currentsVegetative patientsTemporal expectationsModern eraWilder PenfieldConsciousnessEvolving viewsBrain injuryDisordersVariable perspectiveSystems of careStatic entities
2008
Neuroethics and Neuroimaging: Moving Toward Transparency
Fins J. Neuroethics and Neuroimaging: Moving Toward Transparency. The American Journal Of Bioethics 2008, 8: 46-52. PMID: 18853386, DOI: 10.1080/15265160802334490.Peer-Reviewed Original ResearchConceptsDisorders of consciousnessDiagnostic nosologyNeural mechanismsMinimally conscious stateWorking brainDiagnostic categoriesNeuroimaging findingsTherapeutic agendaDiagnostic refinementNeuroimagingAge of neuroscienceMechanisms of recoveryBrain injuryAssessment ScaleTranslation of research findingsDisordersBrainConscious stateEthical conduct of researchClinical contextConduct of researchResearch findingsFunctional levelEthical conductNosologyNeuroimaging and Disorders of Consciousness: Envisioning an Ethical Research Agenda
Fins* J, Illes* J, Bernat** J, Hirsch** J, Laureys** S, Murphy** E. Neuroimaging and Disorders of Consciousness: Envisioning an Ethical Research Agenda. The American Journal Of Bioethics 2008, 8: 3-12. PMID: 18853371, DOI: 10.1080/15265160802318113.Peer-Reviewed Original ResearchMeSH KeywordsBrain InjuriesConsciousnessConsciousness DisordersCooperative BehaviorDiagnostic Techniques, NeurologicalEthics, ResearchHuman ExperimentationHumansNervous System Physiological PhenomenaNeurologyPainPatient SelectionPersistent Vegetative StatePhysical StimulationResearch DesignSocial JusticeThird-Party ConsentConceptsDisorders of consciousnessEthical research agendaEthical reflectionEthical framesScientific progressScientific backdropConsciousnessConscious stateLimited stateInterdisciplinary approachWorking meetingsResearch agendaEthicsNeuroethicsNeuroscientistsReflectionBackdropStanford UniversityAgendaUnderstandingConferenceTranslationSchiff et al. reply
Schiff N, Giacino J, Kalmar K, D.Victor J, Baker K, Gerber M, Fritz B, Eisenberg B, Biondi T, O’Connor J, Kobylarz E, Farris S, Machado A, McCagg C, Plum F, Fins J, Rezai A. Schiff et al. reply. Nature 2008, 452: e1-e2. DOI: 10.1038/nature06575.Peer-Reviewed Original Research
2007
Neuroimaging and neuroethics: clinical and policy considerations
Fins J, Shapiro Z. Neuroimaging and neuroethics: clinical and policy considerations. Current Opinion In Neurology 2007, 20: 650-654. PMID: 17992084, DOI: 10.1097/wco.0b013e3282f11f6d.Peer-Reviewed Original ResearchConceptsMinimally conscious stateMechanisms of recoveryBrain injuryConscious stateMechanisms of brain recoveryFunctional imagingDiagnostic nosologyDisorders of consciousnessNeuroimaging responsesDiagnostic categoriesSevere brain injuryPremature disseminationNeuroimagingBrain recoveryDisordersHealth policyConsciousness disorderEthical implicationsTherapeutic approachesClinical diagnosisClinical practiceCliniciansPatientsNosologyImplicationsLate recovery from the minimally conscious state
Fins J, Schiff N, Foley K. Late recovery from the minimally conscious state. Neurology 2007, 68: 304-307. PMID: 17242341, DOI: 10.1212/01.wnl.0000252376.43779.96.Peer-Reviewed Original ResearchConceptsMinimally conscious stateDisorders of consciousnessDiagnosis of persistent vegetative stateLate recoveryInvestigation of patientsPersistent vegetative stateConscious statePrognostic markerTraumatic injuryPublic confusionMeeting participantsResearch initiativesDiagnostic testsAxonal regrowthPublished studiesParticipantsPatientsMechanisms of recoveryVegetative stateMeetingInitial focus