2024
A simple, field-applicable method to increase the infectivity of wild isolates of Plasmodium falciparum to mosquito vectors
Ouattara S, Hien D, Nao E, Paré P, Guissou E, Cohuet A, Morlais I, Yerbanga R, Dabiré K, Ouédraogo J, Mouline K, Lefèvre T. A simple, field-applicable method to increase the infectivity of wild isolates of Plasmodium falciparum to mosquito vectors. Malaria Journal 2024, 23: 135. PMID: 38711028, PMCID: PMC11075210, DOI: 10.1186/s12936-024-04969-0.Peer-Reviewed Original ResearchConceptsDirect membrane feeding assaysGametocyte densityHuman-to-mosquito transmissionDonor bloodLow gametocyte densitiesMembrane feeding assaysPlasmodium falciparum gametocytesTransmission-blocking interventionsWhole bloodInfection rateFalciparum gametocytesInfectious reservoirNaive serumAsymptomatic individualsMosquito infectionHuman donorsRemoval of plasmaEndemic countriesSerumPlasmodiumParasite isolatesInfectionBlood treatmentGametocytesPlasma volume
2021
Contrasting effects of the alkaloid ricinine on the capacity of Anopheles gambiae and Anopheles coluzzii to transmit Plasmodium falciparum
Hien D, Paré P, Cooper A, Koama B, Guissou E, Yaméogo K, Yerbanga R, Farrell I, Ouédraogo J, Gnankiné O, Ignell R, Cohuet A, Dabiré R, Stevenson P, Lefèvre T. Contrasting effects of the alkaloid ricinine on the capacity of Anopheles gambiae and Anopheles coluzzii to transmit Plasmodium falciparum. Parasites & Vectors 2021, 14: 479. PMID: 34526119, PMCID: PMC8444468, DOI: 10.1186/s13071-021-04992-z.Peer-Reviewed Original ResearchConceptsAnopheles coluzziiAnopheles gambiaeCastor bean Ricinus communisSecondary phytochemicalsKey phenotypic traitsNovel control agentsPlant-derived sugarsAbility of mosquitoesPhenotypic traitsPlasmodium falciparumParasite growth ratePlant sugarsPlant nectarFeeding assaysControl agentsMosquito physiologyGrowth rateAnopheles speciesSensu latoAnopheles gambiae sensu latoColuzziiGambiae sensu latoPutative roleP. falciparum infectionMosquito survivalInsecticide resistance profiles in malaria vector populations from Sud-Kivu in the Democratic Republic of the Congo
N'Do S, Bandibabone J, Soma D, Musaka B, Prudhomme J, Habamungu C, Namountougou M, Sangaré I, Kientega M, Kaboré D, Bayili K, Yerbanga R, Diabate A, Dabire R, Ouedraogo J, Belem A, Boëte C, Guardiola-Claramonte M, Chimanuka B. Insecticide resistance profiles in malaria vector populations from Sud-Kivu in the Democratic Republic of the Congo. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 2021, 115: 1339-1344. PMID: 34324683, DOI: 10.1093/trstmh/trab116.Peer-Reviewed Original ResearchConceptsA. gambiaeInsecticide resistance profileInsecticide resistanceAce-1R mutationMalaria vector populationsVector populationsInsecticide susceptibility bioassaysWild populationsAce-1RPiperonyl butoxideAnopheles gambiaeKdr mutationSusceptibility bioassaysSusceptibility of vectorsMosquito speciesGambiaeAnopheles funestusVector susceptibilitySud-KivuMutationsA. funestusVector control toolsResistance status
2020
High Plasmodium infection intensity in naturally infected malaria vectors in Africa
Bompard A, Da D, Yerbanga S, Morlais I, Awono-Ambéné P, Dabiré R, Ouédraogo J, Lefèvre T, Churcher T, Cohuet A. High Plasmodium infection intensity in naturally infected malaria vectors in Africa. International Journal For Parasitology 2020, 50: 985-996. PMID: 32681932, DOI: 10.1016/j.ijpara.2020.05.012.Peer-Reviewed Original ResearchConceptsOocyst-positive mosquitoesInfectious blood mealEfficacy of transmissionControl of malariaWild malaria vectorsMalaria parasite transmissionCross-sectional surveyInfection loadSalivary gland sporozoitesMalaria vectorsMalaria endemicityNumber of oocystsInfected mosquitoesMalaria transmissionOocyst prevalenceStrong positive associationPrevalencePositive associationBlood mealOocyst loadInfection intensityEpidemiologyEfficacyParasite transmissionIntervention
2019
Chromatin changes in Anopheles gambiae induced by Plasmodium falciparum infection
Ruiz J, Yerbanga R, Lefèvre T, Ouedraogo J, Corces V, Gómez-Díaz E. Chromatin changes in Anopheles gambiae induced by Plasmodium falciparum infection. Epigenetics & Chromatin 2019, 12: 5. PMID: 30616642, PMCID: PMC6322293, DOI: 10.1186/s13072-018-0250-9.Peer-Reviewed Original ResearchConceptsTranscription factorsHistone modificationsChromatin changesGenome-wide distribution mapsInfection-responsive genesHuman malaria parasite Plasmodium falciparumPeptide-encoding genesMalaria parasite Plasmodium falciparumHistone modification enrichmentDorsal transcription factorParasite Plasmodium falciparumImmunity gene expressionJAK/STATHuman malaria parasiteAnopheles gambiae mosquitoesEpigenetic basisFunctional annotationMotif analysisChIP-seqPhenotypic traitsRNA-seqRegulatory elementsGenetic manipulationNatural isolatesAnopheles gambiae
2017
Epigenetic regulation of Plasmodium falciparum clonally variant gene expression during development in Anopheles gambiae
Gómez-Díaz E, Yerbanga R, Lefèvre T, Cohuet A, Rowley M, Ouedraogo J, Corces V. Epigenetic regulation of Plasmodium falciparum clonally variant gene expression during development in Anopheles gambiae. Scientific Reports 2017, 7: 40655. PMID: 28091569, PMCID: PMC5238449, DOI: 10.1038/srep40655.Peer-Reviewed Original ResearchConceptsAP2 transcription factorsVar genesTranscription factorsAntisense long non-coding RNAProtein-coding transcriptsSingle var geneLong non-coding RNAsVariant gene expressionNon-coding RNAsVar gene transcriptionChromatin statePhenotypic plasticityHistone modificationsMultigene familyEpigenetic regulationAntisense lncRNAsGene transcriptionAnopheles gambiaeGene expressionIntraerythrocytic cycleMosquito hostSporogonic developmentTranscriptionParasite developmentGenes
2016
Neemazal ® as a possible alternative control tool for malaria and African trypanosomiasis?
Yerbanga R, Rayaisse J, Vantaux A, Salou E, Mouline K, Hien F, Habluetzel A, Dabiré R, Ouédraogo J, Solano P, Lefèvre T. Neemazal ® as a possible alternative control tool for malaria and African trypanosomiasis? Parasites & Vectors 2016, 9: 263. PMID: 27146309, PMCID: PMC4857419, DOI: 10.1186/s13071-016-1538-x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnophelesAzadirachtaFeeding BehaviorFemaleInsecticidesMaleMicePlant ExtractsTsetse FliesConceptsAfrican trypanosomiasisEffect of bloodOral dosesBehavioral alterationsConclusionThis studyAnthropophilic rateDifferent dosesMembrane feedingAlternative control toolsDosesCalf odourPromising activityMalariaMiceBloodDoseVector control programsHost stimuliAdditional researchControl programsPlant remediesBehavioral responsesG. palpalis gambiensisTrypanosomiasisBloodmeal
2015
Plasmodium transmission blocking activities of Vernonia amygdalina extracts and isolated compounds
Abay S, Lucantoni L, Dahiya N, Dori G, Dembo E, Esposito F, Lupidi G, Ogboi S, Ouédraogo R, Sinisi A, Taglialatela-Scafati O, Yerbanga R, Bramucci M, Quassinti L, Ouédraogo J, Christophides G, Habluetzel A. Plasmodium transmission blocking activities of Vernonia amygdalina extracts and isolated compounds. Malaria Journal 2015, 14: 288. PMID: 26208861, PMCID: PMC4513948, DOI: 10.1186/s12936-015-0812-2.Peer-Reviewed Original ResearchConceptsEarly sporogonic stagesOocyst prevalenceVivo transmissionHuman parasite P. falciparumP. berghei parasitesMalaria control toolsAnopheles stephensi mosquitoesEthanolic leaf extractVernonia amygdalina extractPreventive treatmentBerghei parasitesField isolatesAnopheles coluzzii mosquitoesParasite P. falciparumP. falciparumBackgroundMedicinal plantsStephensi mosquitoesPlasmodium transmissionHerbal medicineMurine parasitePlasmodium falciparumLeaf extractPrevalenceCytotoxic effectsSporogonic stagesAntibiotics in ingested human blood affect the mosquito microbiota and capacity to transmit malaria
Gendrin M, Rodgers F, Yerbanga R, Ouédraogo J, Basáñez M, Cohuet A, Christophides G. Antibiotics in ingested human blood affect the mosquito microbiota and capacity to transmit malaria. Nature Communications 2015, 6: 5921. PMID: 25562286, PMCID: PMC4338536, DOI: 10.1038/ncomms6921.Peer-Reviewed Original ResearchConceptsMass drug administration programsHigh antibiotic usageDrug administration programsBlood of childrenAnopheles gambiae mosquitoesMalaria infectionAntibiotic exposureMosquito bitesHigh riskAntibiotic usageMalaria reductionGut microbiotaMalaria transmissionCommunicable diseasesPlasmodium falciparumBloodIngested bloodGambiae mosquitoesAntibioticsHuman bloodDisease transmissionDiseaseMosquito survivalMosquito microbiotaVectorial capacity
2014
Experimental study of the relationship between Plasmodium gametocyte density and infection success in mosquitoes; implications for the evaluation of malaria transmission-reducing interventions
Da D, Churcher T, Yerbanga R, Yaméogo B, Sangaré I, Ouedraogo J, Sinden R, Blagborough A, Cohuet A. Experimental study of the relationship between Plasmodium gametocyte density and infection success in mosquitoes; implications for the evaluation of malaria transmission-reducing interventions. Experimental Parasitology 2014, 149: 74-83. PMID: 25541384, DOI: 10.1016/j.exppara.2014.12.010.Peer-Reviewed Original ResearchConceptsGametocyte densityParasite densityBlood samplesInfected bloodMouse bloodInfectious blood samplesMembrane feeding assaysPlasmodium berghei infectionTransmission-reducing interventionsPlasmodium falciparum samplesBlood dilutionEvaluation of transmissionInfected mouse bloodBerghei infectionPlasmodium infectionMosquito infectivityAnopheles coluzzii mosquitoesInhibitory factorMonoclonal antibodiesBloodAccurate relative measuresInfectionUninfected bloodHost bloodColuzzii mosquitoesTransmission blocking activity of Azadirachta indica and Guiera senegalensis extracts on the sporogonic development of Plasmodium falciparum field isolates in Anopheles coluzzii mosquitoes
Yerbanga R, Lucantoni L, Ouédraogo R, Da D, Yao F, Yaméogo K, Churcher T, Lupidi G, Taglialatela-Scafati O, Gouagna L, Cohuet A, Christophides G, Ouédraogo J, Habluetzel A. Transmission blocking activity of Azadirachta indica and Guiera senegalensis extracts on the sporogonic development of Plasmodium falciparum field isolates in Anopheles coluzzii mosquitoes. Parasites & Vectors 2014, 7: 185. PMID: 24735564, PMCID: PMC3996177, DOI: 10.1186/1756-3305-7-185.Peer-Reviewed Original ResearchConceptsOocyst prevalencePlasmodium falciparum fieldMalaria control toolsLate-stage gametocytesAnopheles coluzzii femalesEvidence of transmissionPharmacological strategiesAntiplasmodial effectCombination treatmentAnopheles coluzzii mosquitoesAntimalarial drugsMalaria controlMalaria parasitesPlasmodium falciparumMembrane feedingMosquito midgutHerbal formulationsGuiera senegalensisEthyl acetate extractPlant extractsEthanol extractHuman hostColuzzii mosquitoesNeem tree Azadirachta indicaOocyst density
2013
Comparison of field-based xenodiagnosis and direct membrane feeding assays for evaluating host infectiousness to malaria vector Anopheles gambiae
Gouagna L, Yao F, Yameogo B, Dabiré R, Ouédraogo J. Comparison of field-based xenodiagnosis and direct membrane feeding assays for evaluating host infectiousness to malaria vector Anopheles gambiae. Acta Tropica 2013, 130: 131-139. PMID: 24262642, DOI: 10.1016/j.actatropica.2013.10.022.Peer-Reviewed Original ResearchConceptsMosquito bitesOocyst infectionDirect membrane feeding assaysInfectious mosquito bitesAnopheles mosquitoesMembrane feeding assaysMalaria-endemic areasLow gametocyte densitiesCross-sectional surveyGametocyte densityEndemic areasDay 7Classical microscopic examinationHost infectiousnessBlood smearsOocyst prevalenceXenodiagnosisHost skinMembrane feederInfectionInfectious individualsInfectiousnessMicroscopic examinationHuman subjectsChildrenAnti-Pfs25 Human Plasma Reduces Transmission of Plasmodium falciparum Isolates That Have Diverse Genetic Backgrounds
Da D, Dixit S, Sattabonkot J, Mu J, Abate L, Ramineni B, Ouedraogo J, MacDonald N, Fay M, Su X, Cohuet A, Wu Y. Anti-Pfs25 Human Plasma Reduces Transmission of Plasmodium falciparum Isolates That Have Diverse Genetic Backgrounds. Infection And Immunity 2013, 81: 1984-1989. PMID: 23509152, PMCID: PMC3676035, DOI: 10.1128/iai.00016-13.Peer-Reviewed Original ResearchConceptsPhase 1 trialParasite isolatesMalaria transmission-blocking vaccineTransmission-reducing activityTransmission-blocking activityPlasmodium falciparum isolatesTransmission-blocking vaccinesPlasmodium falciparum parasitesLimited sequence polymorphismPfs25 antibodiesMontanide ISA51Immune plasmaNonimmune controlsRecombinant Pfs25Falciparum isolatesPfs25 geneFalciparum parasitesGenetic backgroundPatientsBurkina FasoPfs25VaccineTrialsNucleotide polymorphismsIsolates
2012
Multiple Insecticide Resistance in Anopheles gambiae s.l. Populations from Burkina Faso, West Africa
Namountougou M, Simard F, Baldet T, Diabaté A, Ouédraogo J, Martin T, Dabiré R. Multiple Insecticide Resistance in Anopheles gambiae s.l. Populations from Burkina Faso, West Africa. PLOS ONE 2012, 7: e48412. PMID: 23189131, PMCID: PMC3506617, DOI: 10.1371/journal.pone.0048412.Peer-Reviewed Original ResearchConceptsGlutathione S-transferaseGambiae populationsInsecticide resistanceNon-specific esterasesResistance phenotypeAce-1 locusInsecticide resistance phenotypeTarget-site mutationsVector populationsAnopheles gambiae populationsMajor malaria vectorMultiple insecticide resistanceMultiple resistance phenotypesPhenotypic diversityMosquito vector populationsKnockdown resistanceResistant allelesS formAnopheles gambiae s.Insecticidal compoundsGambiae mosquitoesSite variationMultiple resistance mechanismsPutative combinationS-transferase
2010
Patterns of sugar feeding and host plant preferences in adult males of An. gambiae (Diptera: Culicidae)
Gouagna L, Poueme R, Dabiré K, Ouédraogo J, Fontenille D, Simard F. Patterns of sugar feeding and host plant preferences in adult males of An. gambiae (Diptera: Culicidae). Journal Of Vector Ecology 2010, 35: 267-276. PMID: 21175931, DOI: 10.1111/j.1948-7134.2010.00082.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnophelesBurkina FasoCarbohydratesEcosystemFeeding BehaviorInsect VectorsMalePlantsConceptsHost plant preferenceY-tube olfactometer assaysSugar sourcesSugar feedingGambiae s.Olfactory response patternsPeri-domestic habitatsDistribution of AnPlant preferenceIndividual plantsNearby plantsOlfactometer assaysMale mosquitoesWestern Burkina FasoUnstudied interactionSenna siameaNatural sugar sourcesPlantsNatural conditionsGambiaeOdor cuesCassia sieberianaFirst evidenceMangifera indicaLaboratory conditionsGenetic variation in human HBB is associated with Plasmodium falciparum transmission
Gouagna L, Bancone G, Yao F, Yameogo B, Dabiré K, Costantini C, Simporé J, Ouedraogo J, Modiano D. Genetic variation in human HBB is associated with Plasmodium falciparum transmission. Nature Genetics 2010, 42: 328-331. PMID: 20305663, DOI: 10.1038/ng.554.Peer-Reviewed Original Research
2008
Dynamics of multiple insecticide resistance in the malaria vector Anopheles gambiae in a rice growing area in South-Western Burkina Faso
Dabiré K, Diabaté A, Djogbenou L, Ouari A, N'Guessan R, Ouédraogo J, Hougard J, Chandre F, Baldet T. Dynamics of multiple insecticide resistance in the malaria vector Anopheles gambiae in a rice growing area in South-Western Burkina Faso. Malaria Journal 2008, 7: 188. PMID: 18817564, PMCID: PMC2564969, DOI: 10.1186/1475-2875-7-188.Peer-Reviewed Original ResearchConceptsVallée du KouKdr mutationResistance mechanismsM formSouth-western Burkina FasoInsecticide resistance mechanismsS populationInsecticide resistance mutationsMolecular forms MMultiple insecticide resistanceSingle point mutationMalaria vector AnophelesS formAnopheles gambiaeGambiae populationsInsecticide resistanceMain malaria vectorResistant populationsRainy seasonOxyanion holeVector AnophelesPoint mutationsGambiaeMolecular formsMultiple resistance mechanisms
2006
Personal protection of long lasting insecticide-treated nets in areas of Anopheles gambiae s.s. resistance to pyrethroids
Dabiré R, Diabaté A, Baldet T, Paré-Toé L, Guiguemdé R, Ouédraogo J, Skovmand O. Personal protection of long lasting insecticide-treated nets in areas of Anopheles gambiae s.s. resistance to pyrethroids. Malaria Journal 2006, 5: 12. PMID: 16472385, PMCID: PMC1402300, DOI: 10.1186/1475-2875-5-12.Peer-Reviewed Original ResearchConceptsBlood-fed mosquitoesBlood feeding rateMalaria vector AnBetter efficacyGambiae s.Control housesLLINsELISA analysisEfficacyEntomological parametersAnopheles gambiae s.Personal protectionBlood mealNETT studyOlysetIntervention housesPermaNetKDR geneVector AnControl conditionMosquitoesPrevention capacityStudy villagesHigher numberMolecular forms
2004
First report of a kdr mutation in Anopheles arabiensis from Burkina Faso, West Africa.
Diabaté A, Baldet T, Chandre F, Dabire K, Simard F, Ouedraogo J, Guillet P, Hougard J. First report of a kdr mutation in Anopheles arabiensis from Burkina Faso, West Africa. Journal Of The American Mosquito Control Association 2004, 20: 195-6. PMID: 15264630.Peer-Reviewed Original Research
2003
Natural swarming behaviour of the molecular M form of Anopheles gambiae
Diabate A, Baldet T, Brengues C, Kengne P, Dabire K, Simard F, Chandre F, Hougard J, Hemingway J, Ouedraogo J, Fontenille D. Natural swarming behaviour of the molecular M form of Anopheles gambiae. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 2003, 97: 713-716. PMID: 16117970, DOI: 10.1016/s0035-9203(03)80110-4.Peer-Reviewed Original Research