2022
Preventive small-quantity lipid-based nutrient supplements reduce severe wasting and severe stunting among young children: an individual participant data meta-analysis of randomized controlled trials
Dewey K, Arnold C, Wessells K, Prado E, Abbeddou S, Adu-Afarwuah S, Ali H, Arnold B, Ashorn P, Ashorn U, Ashraf S, Becquey E, Brown K, Christian P, Colford J, Dulience S, Fernald L, Galasso E, Hallamaa L, Hess S, Humphrey J, Huybregts L, Iannotti L, Jannat K, Lartey A, Le Port A, Leroy J, Luby S, Maleta K, Matias S, Mbuya M, Mridha M, Nkhoma M, Null C, Paul R, Okronipa H, Ouédraogo J, Pickering A, Prendergast A, Ruel M, Shaikh S, Weber A, Wolff P, Zongrone A, Stewart C. Preventive small-quantity lipid-based nutrient supplements reduce severe wasting and severe stunting among young children: an individual participant data meta-analysis of randomized controlled trials. American Journal Of Clinical Nutrition 2022, 116: 1314-1333. PMID: 36045000, DOI: 10.1093/ajcn/nqac232.Peer-Reviewed Original ResearchMeSH KeywordsCachexiaChildChild, PreschoolDietary SupplementsGrowth DisordersHumansInfantLipidsNutrientsRandomized Controlled Trials as TopicConceptsSmall-quantity lipid-based nutrient supplementsLipid-based nutrient supplementsSevere wastingIndividual participant dataParticipant dataPassive control armStudy-level characteristicsSevere stuntingMo of ageFixed-effects modelNutrient supplementsHealthy child growthControl armChildren 6Inclusion criteriaEffect modifiersPreventive interventionsChild wastingGreater burdenSubgroup estimatesWastingChild growthYoung childrenStuntingRelative reduction
2016
Comparison of Preventive and Therapeutic Zinc Supplementation in Young Children in Burkina Faso: A Cluster-Randomized, Community-Based Trial 1–3
Becquey E, Ouédraogo C, Hess S, Rouamba N, Prince L, Ouédraogo J, Vosti S, Brown K. Comparison of Preventive and Therapeutic Zinc Supplementation in Young Children in Burkina Faso: A Cluster-Randomized, Community-Based Trial 1–3. Journal Of Nutrition 2016, 146: 2058-2066. PMID: 27489011, DOI: 10.3945/jn.116.230128.Peer-Reviewed Original ResearchConceptsTherapeutic zinc supplementationPreventive zinc supplementationZinc supplementationNonintervention controlsMalaria incidenceDiarrhea incidenceZinc-deficient populationsPrevalence of diarrheaPlasma zinc concentrationTreatment of diarrheaPrimary outcomeBurkinabe childrenMSC groupLower incidenceNIC groupStudy groupTreatment groupsPrimary analysisControl groupDiarrheaIncidenceSupplementationTrial 1Young childrenFever
2015
Small-Quantity Lipid-Based Nutrient Supplements, Regardless of Their Zinc Content, Increase Growth and Reduce the Prevalence of Stunting and Wasting in Young Burkinabe Children: A Cluster-Randomized Trial
Hess S, Abbeddou S, Jimenez E, Somé J, Vosti S, Ouédraogo Z, Guissou R, Ouédraogo J, Brown K. Small-Quantity Lipid-Based Nutrient Supplements, Regardless of Their Zinc Content, Increase Growth and Reduce the Prevalence of Stunting and Wasting in Young Burkinabe Children: A Cluster-Randomized Trial. PLOS ONE 2015, 10: e0122242. PMID: 25816354, PMCID: PMC4376671, DOI: 10.1371/journal.pone.0122242.Peer-Reviewed Original ResearchMeSH KeywordsBurkina FasoDietary SupplementsFemaleGrowth DisordersHumansInfantLipidsMaleWasting SyndromeZincConceptsSmall-quantity lipid-based nutrient supplementsNon-intervention cohortPlacebo tabletsLipid-based nutrient supplementsYoung Burkinabe childrenOral rehydration saltsPrevalence of stuntingIncidence of diarrheaCluster-randomized trialPlasma zinc concentrationMonths of ageBaseline hemoglobinMorbidity surveillanceNutrient supplementsStandard careDiarrhea treatmentRehydration saltsAnemia prevalenceBurkinabe childrenIllness surveillanceAntimalarial therapyIntervention groupIllness treatmentZinc tabletsZinc levels